1.A Rare Case of Tumor-to-Tumor Metastasis of Thyroid Papillary Carcinoma within a Pulmonary Adenocarcinoma.
Taebum LEE ; Yoon Jin CHA ; Sangjeong AHN ; Joungho HAN ; Young Mog SHIM
Journal of Pathology and Translational Medicine 2015;49(1):78-80
No abstract available.
Adenocarcinoma*
;
Carcinoma, Papillary*
;
Neoplasm Metastasis*
;
Thyroid Gland*
2.Color Doppler Image of Thyroid Nodule: Differentiation Between Benign and Malignant Lesion.
Jong Pil YOON ; Hyun Sook HONG ; Young Tae JEON ; Seo Hee KIM ; Myung Hee YOO ; Dae Ho KIM ; Hae Kyung LEE ; Kui Hyang KWON
Journal of the Korean Radiological Society 1996;35(5):679-683
PURPOSE: To assess the utility of color Doppler sonography in the differential diagnosis of thyroid nodules. MATERIALS AND METHODS: Fifty patients with thyroid nodules(10 cases of follicular adenoma, 12 of adenomatous hyperplasia, 21 of papillary adenocarcinoma, and 7 of follicular adenocarcinoma) were analyzed. Colour signal analysis was performed by inspecting the signals in and around the nodules, and these were graded from 0 to III according to the degree of vascularity in internal and marginal blood flow. Peak systoic velocity (PSV) and resistive index (RI) in internal vascularity were used to analyse the flow signal. RESULTS: Internal colorsignals of malignant lesions tended to be high grade, whereas those of benign lesions tended to be low grade, with statistical significance(P<0.05). In spectral wave analysis, correlation between PSV and malignancy of thyroid nodules was statistically significant(P<0.05). The value of RI did not correlate with the malignancy of nodules, but tended to show a meaningful difference. CONCLUSIONS: Although further studies may be required, color Dopplersonography using color signal analysis and flow signals analysis is a useful imaging modality for the differentiation of benign and malignant lesions of thyroid nodules.
Adenocarcinoma, Papillary
;
Adenoma
;
Diagnosis, Differential
;
Humans
;
Thyroid Gland*
;
Thyroid Nodule*
3.Two cases of papillary adenocarcinoma originating in the thyroglossal duct remnants.
Jong Ouck CHOI ; Do Kwang JUNG ; Sei Hyun BAIK
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(5):1079-1084
No abstract available.
Adenocarcinoma, Papillary*
4.Problems in the diagnosis of thyroid papillary and follicular carcinoma.
Chinese Journal of Pathology 2007;36(4):220-223
Adenocarcinoma, Follicular
;
diagnosis
;
pathology
;
Adenoma
;
diagnosis
;
pathology
;
Carcinoma, Papillary
;
diagnosis
;
pathology
;
Carcinoma, Papillary, Follicular
;
diagnosis
;
pathology
;
Cell Nucleus
;
pathology
;
Diagnosis, Differential
;
Humans
;
Neoplasm Invasiveness
;
Thyroid Gland
;
pathology
;
Thyroid Neoplasms
;
diagnosis
;
pathology
;
Thyroid Nodule
;
diagnosis
;
Thyroiditis
;
diagnosis
5.Papillary gastric adenocarcinoma.
Jong In YANG ; Jung Mook KANG ; Sun Jung MYUNG ; Dae Hee CHOI
Korean Journal of Medicine 2007;73(2):233-234
No abstract available.
Adenocarcinoma*
;
Adenocarcinoma, Papillary
;
Stomach
6.Cytologic Features of Endometral Papillary Serous Carchinoma.
Gu KONG ; Eun Kyoung HONG ; Jung Dal LEE
Korean Journal of Cytopathology 1990;1(2):121-128
Endometrial papillary serous carcinoma (EPSC) is a distinct variant of endometrial adenocarcinoma that histologically resembles ovarian serous papillary adenocarcinoma and has an aggressive clinical course. Usually, the tumor is diagnosed at the advanced stage. The tumor has well confused with metastatic ovarian tumor of identical histology. Diagnosis of EPSC should be considered when the cervico-vaginal smear reveals numerous papillary clusters of tumor cells with macronucleoli and psammoma bodies. Recently, we have experienced two cases of EPSC diagnosed on cervico-vaginal smears, which revealed characteristic cytologic features including numerous papillary clusters of tumor cells with macronucleoli. The cytologic diagnoses were confirmed on histologic sections.
Adenocarcinoma
;
Adenocarcinoma, Papillary
;
Diagnosis
7.Recently identified renal cell carcinoma.
Ming ZHAO ; Xiao-dong TENG ; Ke SUN ; Liang CHENG
Chinese Journal of Pathology 2013;42(7):478-482
Adenocarcinoma, Follicular
;
metabolism
;
pathology
;
Adenoma, Chromophobe
;
metabolism
;
pathology
;
Adenoma, Oxyphilic
;
metabolism
;
pathology
;
Angiomyoma
;
metabolism
;
pathology
;
Biomarkers, Tumor
;
metabolism
;
Carcinoma, Papillary
;
metabolism
;
pathology
;
Carcinoma, Renal Cell
;
classification
;
metabolism
;
pathology
;
ultrastructure
;
Diagnosis, Differential
;
Humans
;
Kidney Neoplasms
;
classification
;
metabolism
;
pathology
;
ultrastructure
;
Thyroid Neoplasms
;
metabolism
;
pathology
8.Carcinoid Tumors of the Gastrointestinal Tract: Analysis of 36 Cases.
Kyeong Cheon JUNG ; Hee Sung KIM ; Sang Yong SONG ; Ghee Young CHOE ; Yong Il KIM
Korean Journal of Pathology 1996;30(5):396-407
We reviewed a total of 36 cases of gastrointestinal carcinoid tumors during a period of ten and a half years at Seoul National University Hospital, looking at their histologic and ultrastructural features, as well as immunohistochemical results, then we correlated these with location. The primary sites of carcinoid tumors were rectum(39%), stomach(25%), appendix(22%), small intestine(8%) and colon(6%), in order of frequency. The predominant histologic types by organ were mixed and solid(A) types in all location, the solid type(type A) in the stomach, and tubular type(type C) in the rectum. Six out of 8 cases of appendiceal carcinoid were type A and the other two cases were mucinous carcinoid. Tubular adenoma or adenocarcinoma was associated with 36% of the rectal carcinoids, with one case of carcinoid in the small intestine, and one(11%) of the gastric carcinoids was found near an adenocarcinoma. Metastasis was found in one case of ileal carcinoid(100%), one case of cecal carcinoid, 3 of gastric carcinoid(33%) and 2 of rectal carcinoid(14%). Primary tumor size ranged from 1 to 7 cm. Tumor necrosis and endolymphatic tumor emboli were found in 57% and 43% of the metastatic carcinoids, respectively. PCNA index showed a borderline significant difference between metastatic and nonmetastatic groups(P value=0.063). The low prevalence of appendiceal carcinoid and the relatively high prevalence of gastric-rectal carcinoid may reflect a low chance of incidental appendectomy and frequent detection of gastrointestinal endoscopy.
Adenocarcinoma
;
Adenoma
;
Neoplasm Metastasis
9.A Case of Low-grade Papillary Adenocarcinoma of the Nasopharynx.
Sang Joon LEE ; Phil Sang CHUNG ; Eun Seok LIM ; Mi Seon KWON
Korean Journal of Otolaryngology - Head and Neck Surgery 2005;48(7):937-939
Low-grade nasopharyngeal papillary adenocarcinoma is a very rare nasopharyngeal, surface epithelium-derived malignant tumor characterized with adenocarcinomatous differentiation and an indolent biological behavior. We report a case of 36-year old female presenting a papillary adenocarcinoma of the nasopharynx. The tumor was of a 0.5 cm sized exophytic mass located on the nasopharyngeal mucosa near the posterior choanal septum. Because of the histologic similarities with thyroid papillary carcinoma, it was necessary to rule out metastasis from thyroid by immunohistochemical staining for thyroglobulin. Surgical excision was done via transpalatal approach; mass was removed with a clear resection margin.
Adenocarcinoma, Papillary*
;
Adult
;
Carcinoma, Papillary
;
Female
;
Humans
;
Mucous Membrane
;
Nasopharynx*
;
Neoplasm Metastasis
;
Thyroglobulin
;
Thyroid Gland
10.Relationship between E-CD and Snail expressions and tumor invasion, metastasis and prognosis in colorectal cancer.
Bo-an ZHENG ; Gao-li DENG ; Quan-jin DONG ; Zhong-sheng ZHAO ; Yong-chuan DENG
Chinese Journal of Oncology 2010;32(2):111-116
OBJECTIVETo study the E-CD and Snail expressions in colorectal cancer and their relationship with colorectal cancer invasion, metastasis and prognosis.
METHODSImmunohistochemical staining (EnVision) was used to detect the E-CD and Snail expressions in 30 normal colorectal mucosa, 30 colorectal adenoma and 142 colorectal cancer tissues.
RESULTSE-CD in the normal colorectal mucosa was strongly positive expressed (90.0%), significantly higher than that in colorectal adenomas (63.3%) and colorectal cancer tissues (41.5%). E-CD expression was significantly related to tumor differentiation, invasion depth, vascular invasion, lymph node metastasis and Dukes' stage (P < 0.05), but not to the patients' age, gender, tumor size and tumor histological type (P > 0.05). The 1-, 3- and 5-year survival rates of the E-CD positive patients with colorectal cancer were significantly higher than that in E-CD negative patients. The positive expression rate of Snail in colorectal cancer tissues (52.1%) was significantly higher than that in normal colorectal mucosa (6.7%) and colorectal adenomas (26.7%, P < 0.05). The snail expression was significantly correlated to tumor histological type, differentiation, invasion depth, vascular invasion, lymph node metastasis and Duke's stage (P < 0.05), but not to patients' age, sex and tumor size (P > 0.05). The 1-, 3- and 5-year survival rates of Snail negative patients with colorectal cancer was significantly higher than that in patients with positive expression (P < 0.05). The expressions of E-CD and Snail in colorectal cancer tissues were inversely correlated (P < 0.05). Cox multivariate analysis showed that E-CD and Snail can be used as independent prognostic indicators (P < 0.05).
CONCLUSIONE-CD and Snail expressions in colorectal cancer are related to the tumor invasion, metastasis and prognosis. Low expression of E-CD and high expression of Snail are related to the advanced stage, and poor prognosis in colorectal cancer patients. E-CD and Snail can be used as independent prognostic indicators.
Adenocarcinoma ; metabolism ; pathology ; Adenocarcinoma, Mucinous ; metabolism ; pathology ; Adenocarcinoma, Papillary ; metabolism ; pathology ; Adenoma ; metabolism ; Adolescent ; Adult ; Aged ; Cadherins ; metabolism ; Colorectal Neoplasms ; metabolism ; pathology ; Female ; Humans ; Intestinal Mucosa ; metabolism ; pathology ; Lymphatic Metastasis ; Male ; Middle Aged ; Neoplasm Invasiveness ; Neoplasm Metastasis ; Neoplasm Staging ; Prognosis ; Proportional Hazards Models ; Snail Family Transcription Factors ; Survival Rate ; Transcription Factors ; metabolism ; Young Adult