To compare the impact of different incision positions of phacoemulsification cataract exaction on corneal astigmatism.
●METHODS: Totally 412 patients ( 456 eyes) who had undergone the phacoemulsification and lOL implantation from June 2006 to June 2013 were randomly divided into two groups (each 228 eyes): observation group (incision above the middle of the limbus for the rule astigmatism, at the temporal for against the rule astigmatism, at the top of the temporal regulation on the maximum curvature of the meridian of the cornea for oblique astigmatism, at the top of the temporal for patients without astigmatism);control group ( incision at top and middle of limbus), using a 3mm cornea scleral tunnel incision without suture, 2mm from the limbus. Corneal refractive status of preoperative and postoperative at different times were detected by corneal refractive, comparing the impact of different surgical incision on postoperative corneal astigmatism.
●RESULTS:The visual acuity of 1, 3mo postoperative of observation group was significantly better than the control group ( P < 0. 05 ). The average astigmatism of 1, 3mo postoperative of observation group was significantly lower than the control group ( P < 0. 05). Corneal astigmatism 3mo postoperative of observation group was significantly lower than preoperative ( P< 0. 05). Corneal astigmatism 3mo postoperative of control group was significantly higher than preoperative (P<0. 05).
●CONCLUSlON:lncision at the corneal curvature of the largest radial could correct preoperative astigmatism and improve visual acuity to a certain extent.

Objective To investigate therapeutic effect,safety and post transplant immunological reconstitution for patients of lymphoma after autologous bone marrow transplantation and occurrence of Rheumatoid Arthritis.Methods The clinical situation,laboratory index and immunological reconstitution was observed for patients of lymphoma after inductive treatment,BCEA of pretreatment,autologous bone marrow transfusion,G-CSF and radiotherapy to lymph node.Results Recovery of hemopoiesis was observed after 28 days.Disappearance of joint swelling and negative ESR,CRP,IgMRF were observed after 2 months.The patients started to work after 3 months. No recurrence of lymphoma and Rheumatoid Arthritis has been observed until today.Conclusion The autologous bone marrow transplantation was safe and effective for the treatment to patient of lymphoma with rheumatoid arthritis,which was a new method for the treatment to lymphoma and other autoallergic diseases.

Objective Clinical research was made to observe the relationship between idiopathic thrombocytopenic purpura(ITP)and Helicobacter pylori(Hp)and to evaluate the effect of Hp eradication in the treatment of refractory ITP.Methods 13C urea breath test and Hp antibody of serum were made in 48 previously untreated patients with ITP from Department of Hematology of the First Affiliated Hospital of China Medical University during November 2004 to May 2005 years and normal controls consisted of 52 heathy peoples whose gastroscopy was normal.Omeprazole,clarithromycin and amoxicillin were used for Hp eradication to refractory ITP with Hp infection.13C urea breath test,Hp antibody of serum and the level platelet and PAIgG was detected after therapy 4~8 weeks.Results Of 48 cases with ITP,33(68.18%)had Hp infection and 24 of 52(46.12%)normal population had Hp infection,the infection rate of Hp in ITP patients being statistically higher than the control group(P

Objective The dynamic accumulation trend of secondary metabolite in cultivated Spatholobus suberectus Dunn at different growth time was studied to provide scientific basis for confirming its reasonable harvesting time. Methods Ethanol-soluble extractives were measured by the method recorded in Chinese Pharmacopoeia ( A) Appendix XA ( 2010 edition). The content of total flavonoids was tested by ultraviolet spectrophotometer. The contents of protocatechuic acid, catechin, and epicatechin in Spatholobus suberectus Dunn were determined by high performance liquid chromatography ( HPLC). Results The contents of ethanol-soluble extractives, total flavonoids and the major components such as protocatechui cacid, catechin and epicatechin in Spatholobus suberectus Dunn showed increasing trend with the prolongation of growth time. The changes of contents of alcohol-soluble extract, total flavonoids and epicatechin in samples collecting at different months in one year showed a parabolic trend, and the contents reached the peak values from July to September. Catechin content kept increasing continually. The content of ethanol -soluble extractives of Spatholobus suberectus Dunn aged 4-6 years met the requirements of the current edition of Chinese Pharmacopoeia when harvested from July to September. Conclusion It is preliminarily recommended that Spatholobus suberectus Dunn cultivated for more than 7 years is suitable for harvesting, but the optimal harvest period and the harvest month still need to be further studied.

Objective To evaluate different angiocardiographic techniques of congenital heart disease in children. Methods 11045 pediatric patients with congenital heart disease were performed angiocardiography using cut film, cine film and digital subtraction angiography(DSA) equipments. Different angiocardiographic techniques were used. Results The diagnostic accuracy of cut film with conventional AP and lateral views was 80.5%,the diagnostic accuracy of cine film with angulated views was 90.0% and the diagnostic accuracy of DSA using non-ionic contrast medium with angulated views was 96.5%. Conclusion Dynamic picture angiography with digital subtraction using non-ionic contrast medium under rapid injection is the key for claiming the high quality imaging diaguosis of congenital heart disease in children.

Objective To observe the clinical therapeutic effect of benazepril plus betaloc in the treatment of chronic congestive heart failure(CHF).Methods 42 cases with CHF were treated with benazepril plus betaloc,the therapeutic effect was compared with 40 cases treated with benazepril alone.Before and after treatment,to observe the changes of systolic pressure(SBP),diastolic pressure(DBP),heart rate(HR),left ventricular end systolic diameter(LVESd),left ventricular end diastolic diameter(LVEDd) and left ventricular ejection fraction(LVEF) were observed.Results The general effective rate in treatment group and control group was 95.2% and 80.0%,respectively.The SBP,DBP,HR,LVESd and LVEDd in treatment group decreased obviously(P

Objective To understand the relationship between the requirement and the consumption of the health management, and provide the theoretical basis for the developing of China health management. Methods It took the survey to understand the relationship among 152 medical staffs from the six counties surrounding with Shi Jiazhuang downtown. Results 85.5%of medical staffs always and almost accept health advisory and provide health guidance. There are not the direct relationship between the requirement and the consumption(x2 = 9.39,P＞0.05 ). Health advice and guidance are not translated into the concepts of investment on the health management and disease prevention (x2 = 1.69, P＞0.05 ). The medical staffs don't realize it is important to invest on the health. Conclusions Related industries should strengthen the training on the health management, publicize this profession, promote the development of health management services and improve the national health quality.[ Key words] Health promotion ; Needs assessment; Economics

It is significant to carry out standardization of Prescription Technology on Chinese clinical pharmacy,which will not only improve the regulation of traditional Chinese medicine techniques,but also promote the standardization of the pharmaceutical industry an important part of the building. The discussion of seven areas of clinical medicine about Prescription audit, prescription pricing, prescription cope, deployment dose, footnote implementation, regulating review, dispensing explain for standardization will be improving and perfecting the pharmacy service system.

Aim To investigate the effects of osthol on bone marrow stromal stem cells in vitro under the con-ditions of the ability to differentiate into osteoblasts and the case of proliferation. Methods The rat bone marrow sample was obtained,and the all bone marrow cell culture methods were used to separate and collect the stratum of mononuclear cells. The cells were cultured in DMEM containing 10% fetal bovine serum. Three days later the culture medium was changed for the first time. Nine days later,serial subcultivation proceeded. The final concentration of osthol was 1 ? 10 -4,1 ? 10 -5,1 ? 10 -6,1 ? 10 -7 mol?L -1 respectively. MTT method was adopted in proliferation analysis. Under the induced condition,the Alkaline phosphatase activity, calcium salt sediment yield and osteocalcin were meas-ured on 4th,8th,12th,16th day. On the fifteenth day,his-tochemistry dyeing proceeded for calcified tubercle. Total RNA was isolated and the gene expression of bFGF, IGF-1,Osterix and Runx-2 was investigated by RT-Real Time PCR. Results The BMSCs proliferation was refrained by osthol dose-dependently. But it evidently led to osteogenesis. The ALP activity,calcium salt sediment yield and osteocalcin were raised,and calcified tubercle amount was increased. Besides,it also could enhance the mRNA level of bFGF,IGF-1,Osterix and Runx-2. Conclusion The osthol with final concentra-tion of 1 ? 10 -5 mol?L -1 can markedly promote BM-SCs differentiation to osteogenesis. which proves osthol is an active constituent of the traditional Chinese medi-cine Common Cnidium Fruit.

Objective To analyse the mutation of K17 gene in a pedigree with steatocystoma multi-plex. Methods Blood samples were obtained from 3 affected and 3 normal individuals in a family with steatocystoma multiplex, as well as from 50 unrelated healthy individuals. Mutation scanning was carried out by PCR and direct sequencing. Results A heterozygous nucleotide transition (C→T) at position 428 in exon 1 of KI7 gene, which leads to the substitution of CGC (arginine) by TGC (histidine) at codon 94, was detected in the affected individuals, but not in normal family members or the 50 unrelated individuals. Conclusion A missense mutation (428C→T) in KI7 gene has been detected in affected individuals of this family, which seems to be a molecular basis of pathogenesis of steatocystoma multiplex.