No abstract available.
Aged ; Diagnosis, Differential ; Female ; Fluorescein Angiography ; Fundus Oculi ; Humans ; *Intraocular Pressure ; Regional Blood Flow/*physiology ; Retina/*diagnostic imaging ; Retinal Hemorrhage/*diagnosis/physiopathology ; Retinal Vein Occlusion/*diagnosis

Adolescent ; Diagnosis, Differential ; Humans ; Male ; Sturge-Weber Syndrome ; pathology

OBJECTIVETo find out an appraisal method of temperature on the first appearance date of Culex tritaeniorhynchus in spring.

METHODSWhole night collection of mosquitoes mosquitoes (from 18:00 hours to 06:00 hours of the following day) with light traps had been carried out in pig sties every night since 1 March in 1982 - 1992 and 2001 - 2002 in Fengxian area Shanghai. The adult mosquitoes caught were anaesthetized, then identified and counted. The density of mosquitoes was calculated by the average number of mosquitos per one trap and one night. Comparative analysis of the mean daily air temperature at 7 days before, the first appearance date and 1 day after, the first appearance date of Culex tritaeniorhynchus.

RESULTSData of the first appearance data of Culex tritaeniorhynchus were judged to mean daily air temperature and cumulative temperature on the day of the first appearance of Culex tritaeniorhynchus and the day before appearance, or 3 days on the day of the first appearance of Culex tritaeniorhynchus and the two days before appearance and the day since appearance with a difference less than 1 - 2 day (91.7%).

CONCLUSIONThe first appearance of Culex tritaeniorhynchus in spring accompanied with a course of influence by the severe warm air advection from south of China, and lowest mean daily air temperature of the first appearance was 11 degrees. Thus the first appearance data of Culex tritaeniorhynchus could be deduced and rehabilitated from observed values of mean daily air temperature or its forecasting values.

Animals ; China ; Circadian Rhythm ; physiology ; Culex ; physiology ; Seasons ; Temperature

OBJECTIVETo explore the association of 8-hydroxyguanine glycosidase OGG1 Ser326Cys polymorphism with semen quality and the risk of male infertility.

METHODSThis case-control study included 620 idiopathic infertile patients and 385 normal fertile controls. We determined their genotypes by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and analyzed their semen quality by computer-aided semen analysis (CASA).

RESULTSThe individuals with OGG1 326 Cys/Cys showed significantly lower sperm motility and concentration ([52.1 +/- 26.7]% and (3.75 +/- 0.91) x 10(6)/ml, ln transformed value) than the Ser/Ser carriers ([59.0 +/- 21.8] % and (4.12 +/- 0.88) x 10(6)/ml, ln transformed value) (P < 0.05). The risk of male infertility increased 69% in the OGG1 326Cys allele carriers as compared with the Ser carriers (OR = 1.69, 95% CI: 1.24 -2.31).

CONCLUSIONOGG1 326 Ser/Cys polymorphism might contribute to the risk of male infertility in the southern Chinese population.

Adult ; Case-Control Studies ; DNA Glycosylases ; genetics ; Genotype ; Humans ; Infertility, Male ; genetics ; Male ; Middle Aged ; Polymorphism, Single Nucleotide ; Semen Analysis ; Young Adult

Objective To correlate CT findings of secondary hepatic lymphoma with pathology and to evaluate it's clinical value.Methods Nine patients with secondary hepatic lymphoma confirmed by pathology underwent spiral CT scanning and dual-phase dynamic contrast-enhancement scanning before operation, the CT data were reviewed and analysed retrospectively in comparison with surgical and pathological results.Results Twenty-three lesions of secondary hepatic lymphoma in 9 patients were located in the left lobe (9 lesions), the fight lobe (6 lesions),the porta of the liver (5 lesions) and the caudate lobe (3 lesions), respectively.Sixteen of these 23 lesions were distributed over an area near the portal vein, 7 were seattered in the exterior of liver.17 lesions had an ellipsoid contour and 6 showed irregular contour.The diameter of the lesions ranged from 2.7 to 16.5 cm, with a mean diameter of 5.9cm.The tumor demonstrated mild homogeneous dynamic delayed contrasted-enhancement and the CT value of the non-contrast scans, AP phases and PVP phases were 20.7 to 31.5 HU(with a mean value of 25.3 HU), 23.8 to 48.5 HU(with a mean value of 31.9 HU) and 35.3 to 60.2 HU(with a mean value of 47.8 HU) respectively.Intrinsic hepatic vessels could be discerned in 6 lesions.The lesions situated in the perta of the liver encased the portal vessels, but there was no vessel compression or occlusion.Conclusion Recognition of the dynamic CT features of hepatic lymphoma could enhance its diagnostic accuracy.

Objective To explore the application of allergen detection in children with recurrent asthma and its clinical signifi‐cance .Methods The clinical data of 524 cases of children with recurrent asthma in this hospital ,from February 2013 to February 2015 ,were retrospectively analysed .According to age ,these children with recurrent asthma were divided into three groups:250 ca‐ses were enrolled into infants group(0- <1 years old) ,150 cases enrolled into cheepers group(1- <3 years old) ,124 cases were enrolled in children group (≥3 years old) .Children in the three groups were treated with allergen detection ,and positive rates and distribution of allergens were compared among three groups .Results The total positive rate of allergen detection was 39 .69%(208/524) .The positive rate of allergen detection was the highest in children group(66 .13% ) ,and the lowest in infants group (24 .00% ) ,and there were statistically significant differences in the positive rates among the three groups(P<0 .05) .The top 3 common allergens were milk ,household dust mite and cat dander .The positive rates of household dust mite and house dust were the highest in children group ,but lowest in infants group ,there were statistically significant differences in the positive rate among the three groups(P<0 .05) .Conclusion Allergen detection is particularly important for children with recurrent asthma ,which not only could quickly find the etiology of asthma and identify children who are susceptible to asthma ,but also provide references for early intervention in childhood asthma .

The crude toxin was extracted from hypha and culture solution of Phyllosticta commelimecola through three different polarity solvent: benzinum, puncificatum ethyl acetate and chloroform. The result indicated that the toxin secreted by Phyllosticta commelimecola not only was in hypha but also in culture solution and the extracting effect of ethyl acetate was the best. The soybean median and PSK media can be respectively used as solid and liquid culture media to produce toxin and grow mycelium. The optimal cultural conditions for producing toxin were temperature 32℃,cultured period 14d, cultured ways shaking of 150r/min.

Objective To explore a new model of medical humanity education in new situation. Methods Extensive survey was carried out among medical students,and discussion and consultation were hold to faculty and education administers.A new teaching model was established. Results A curriculum system with 1 or 2 core courses supported by some elective courses and social practice is under the process of implementation and achieved preliminary success.Conclusion The medical humanity education should pay attention to the development of connotation instead of pursuing the extension of quantity blindly,which means that students' school work must be eased by focusing on self-study and self-education.Medical students'life path with high-minded personality training should be strengthened.

Objective To investigate the value of tumor-stroma ratio(TSR) in evaluating the prognosis of patients with triple-negative breast cancer (TNBC).Methods A total of 87 patients with TNBC were selected from January 2010 to December 2014 in the Second People's Hospital of Yibin.The TSR was detected by Hematoxylin eosin staining,the patients with TSR ＜50％ were included in the stroma-rich group,and the patients with TSR≥50％ were included in the stroma-rare group.The influencing factors of tumor-free survival and overall survival in TNBC patients were analyzed by COX regression model.The effect of TSR on tumor-free survival and overall survival in TNBC patients was further analyzed by Kaplan-Meier method.Results Among the 87 TNBC patients,there were 38 patients with TSR≥50％ (stroma-rare group) and 49 patients with TSR ＜ 50％ (stroma-rich group).The 5-year tumor-free survival rate and overall survival rate of the 87 TNBC patients was 52.9％ (46/87) and 56.3％ (49/87) respectively.Single factor COX regression analysis showed that the tumor diameter staging,lymph node metastasis,the number of tumors and TSR were significantly correlated with the overall survival rate and tumor-free survival rate of patients with TNBC (P ＜ 0.05).Multivariate COX regression analysis showed that the tumor diameter staging,lymph node metastasis,the number of tumors and TSR were independent risk factors for overall survival rate and tumor-free survival rate of patients with TNBC (P ＜ 0.05).Kaplan-Meier survival analysis showed that the tumor-free survival rate and the overall survival rate of TNBC patients in the stroma-rare group were 68.4％ (26/38) and 73.7％ (28/38),and they were 40.8％ (20/49) and 42.9％ (21/49) in the stroma-rich group.The Log-Rank test showed that the overall survival rate and disease-free survival rate of the TNBC patients in the stroma-rare group were significantly higher than those in the stroma-rich group (x2 =7.788,9.799;P ＜ 0.05).Conclusion TSR is significantly associated with the prognosis of TNBC patients,and it is an independent risk factor for the prognosis of TNBC patients.TSR can be used as an indicator for evaluating the prognosis of TNBC patients.

BACKGROUND: Vincristine is an antimitotic agent used for treatment of leukemia, lymphomas, and cancers. Its main side effect is a dose-related, length-dependent axonal neuropathy.METHODS: We performed electrodiagnostic examinations in 18 children who had been treated with vincristine and who presented with the clinical picture of a peripheral neuropathy.RESULTS: The mean cumulative dose of vincristine was 37.7±26.5 mg/m². Electrodiagnostic examination showed an axonal neuropathy with a length-dependent pattern. All patients showed motor nerve abnormalities and sensory nerve abnormalities were observed in 13 patients (72.2%). The number of affected nerves was 2.67±1.1 (mean±SD) of four motor nerves and 1.5±1.4 of four sensory nerves. The mean reduction of the compound muscle action potential amplitude was 70.9±42.2% in the median nerve and 23.7±20.8% in the peroneal nerve compared to normal value. However, the mean change in the sensory nerve action potential amplitude was 139.9±78.5% in the median nerve and 246.9±169.7% in the superficial peroneal nerve. There was statistically significant difference between amplitude reduction of the compound muscle action potential and sensory nerve action potential.CONCLUSION: The quantitative analysis of electrophysiological motor predominance described differs from the mainly sensory neuropathy reported in adults. Incomplete myelination in motor nerve due to young age may have resulted in greater sensitivity of some nerves to neurotoxic agents.
Action Potentials ; Adult ; Axons ; Child ; Drug Therapy ; Humans ; Leukemia ; Lymphoma ; Median Nerve ; Myelin Sheath ; Pediatrics ; Peripheral Nervous System Diseases ; Peroneal Nerve ; Polyneuropathies ; Precursor Cell Lymphoblastic Leukemia-Lymphoma ; Reference Values ; Vincristine