1.Magnesium Sulfate in the Treatment of Torsade De Pointes.
Cheol Whan LEE ; Jae Joong KIM ; Jae Kwan SONG ; Seong Wook PARK ; Seung Jung PARK ; Jong Koo LEE
Korean Circulation Journal 1994;24(4):617-623
No abstract available.
Magnesium Sulfate*
;
Magnesium*
;
Torsades de Pointes*
2.About uses of magnesium during perioperative period.
Korean Journal of Anesthesiology 2012;62(6):509-511
No abstract available.
Magnesium
;
Perioperative Period
3.About uses of magnesium during perioperative period.
Korean Journal of Anesthesiology 2012;62(6):509-511
No abstract available.
Magnesium
;
Perioperative Period
4.Association of serum magnesium and distal symmetric peripheral neuropathy among Filipino patients with Type 2 Diabetes Mellitus
Marion B. Sarigumba ; Andrea Marie M. Oliva ; Ma. Jocelyn C. Isidro
Philippine Journal of Internal Medicine 2024;62(1):283-290
Objective:
This study aims to determine the association of serum magnesium with distal symmetric peripheral
neuropathy among persons with type 2 diabetes mellitus (DM).
Methodology:
A cross-sectional analytical study among adult Filipinos with Type 2 DM. Logistic regression was used to
determine the association of serum magnesium with DSPN diagnosed by the Michigan Neuropathy Screening Instrument.
The null hypothesis was rejected at 0.05α-level of significance.
Results:
The average serum magnesium levels were similar between those with versus without DSPN (2.06 ± 0.32 vs 2.05
± 0.23, p = 0.873); the same was seen for corrected magnesium. There is insufficient evidence to demonstrate a significant
statistical difference between those with and without DSPN in relation to glycemic control (HbA1c and FBS). Likewise, there
is no significant statistical correlation between serum magnesium levels with HbA1c, FBS, BMI, or duration of diabetes.
Conclusion
This present study could not demonstrate any association between DSPN and serum magnesium, even after
adjusting for age, sex, and comorbidity.
Magnesium
;
Diabetic Neuropathies
5.A Case of Primary Hypomagnesemia.
Kyoung A CHUN ; Sung Pil JANG ; Young Dae HAM ; Jin Hwa JEONG ; Jeong Ho LEE
Journal of the Korean Pediatric Society 2000;43(8):1153-1156
Primary hypomagnesemia is a rare inherited disorder and it is considered to be due to either a defect in the intestinal transport of magnesium or a defect in renal tubular transport. It is important to measure the urinary excretion of magnesium to differentiate the causes of magnesium deficiency. We report here an one-month-old female infant of primary hypomagnesemia who presented generalized tonic-clonic seizures. She had hypomagnesemia(<1.5mg/dL) and several seizure attacks but normal magnesium creatinine ratio in random urine and normal magnesium excretion in 24-hour urine. Continuous oral magnesium supplementation was necessary to avoid the recurrence of symptoms and maintain serum rnagnesium levels.
Creatinine
;
Female
;
Humans
;
Infant
;
Magnesium
;
Magnesium Deficiency
;
Recurrence
;
Seizures
6.A comparison of ritodrine and magnesium sulfate for the suppression of preterm labor.
Tae Bok SONG ; Young Don YOON ; Sang Yook LEE ; Seung Kuk KIM
Korean Journal of Perinatology 1992;3(1):33-41
No abstract available.
Female
;
Magnesium Sulfate*
;
Magnesium*
;
Obstetric Labor, Premature*
;
Pregnancy
;
Ritodrine*
7.A Comparison of Efficacy and Safety of Ritodrine hydrochloride alone and Combined Treatment with Magnesium sulfate in the Management of Preterm Labor.
Young Ah KIM ; Hee Suk KANG ; Soon Ha YANG ; Jong Hwa KIM
Korean Journal of Obstetrics and Gynecology 2002;45(11):1991-1995
OBJECTIVE: This study was designed to compare the efficacy and safety of the ritodrine hydrochloride alone with combined treatment with magnesium sulfate in the management of preterm labor. METHODS: One hundred thirty three singleton pregnancies with preterm labor were treated with either ritodrine hydrochloride (n=97) or ritodrine hydrochloride and magnesium sulfate (n=36). The principal outcomes assessed were delay of duration, maternal-fetal side effects, and fetal outcome. RESULTS: The treatment to delivery time was not statistically different between the ritodrine group and the combined magnesium sulfate group (mean+/-SD 10.7+/-13.0 days, 8.6+/-9.1 days, respectively). The proportion delivered after 48 hours, 72 hours, or 7 days was also not statistically different between two groups (29% vs. 22%, 40% vs. 39%, 60% vs. 64%, respectively). No statistical difference was found in the side effects of treatment or fetal outcomes. CONCLUSION: There was no significant difference in efficacy and safety between ritodrine hydrochloride and combined treatment with magnesium sulfate in the management of preterm labor.
Female
;
Magnesium Sulfate*
;
Magnesium*
;
Obstetric Labor, Premature*
;
Pregnancy
;
Ritodrine*
8.The effect of magnesium sulfate concentration on the effective concentration of rocuronium, and sugammadex-mediated reversal, in isolated left phrenic nerve hemi-diaphragm preparations from the rat.
Choon kyu CHO ; Tae yun SUNG ; Seok Jun CHOI ; Hey ran CHOI ; Yong Beom KIM ; Jung Un LEE ; Hong Seuk YANG
Korean Journal of Anesthesiology 2018;71(5):401-406
BACKGROUND: Perioperative magnesium sulfate (MgSO4) is used for analgesic, anti-arrhythmic, and obstetric purposes. The effects of MgSO4 on the neuromuscular blockade (NMB) induced by rocuronium, and the sugammadex reversal thereof, have not been clearly quantified. We investigated the effect of various MgSO4 concentrations on the NMB by rocuronium, and sugammadex reversal, in isolated left phrenic nerve hemi-diaphragm (PNHD) preparations from the rat. METHODS: Rat PNHD preparations were randomly allocated to one of four groups varying in terms of MgSO4 concentration (1, 2, 3, and 4 mM, each n = 10, in Krebs solution). The train-of-four (TOF) and twitch height responses were recorded mechanomyographically. The preparations were treated with incrementally increasing doses of rocuronium and each group’s effective concentration (EC)50, EC90, and EC95 of rocuronium were calculated via nonlinear regression. Then, sugammadex was administered in doses equimolar to rocuronium. The recovery index, time to T1 height > 95% of control, and the time to a TOF ratio > 0.9 after sugammadex administration were measured. RESULTS: The EC50, EC90, and EC95 of rocuronium fell significantly as the magnesium level increased. The EC50, EC90, and EC95 of rocuronium did not differ between the 3 and 4 mM groups. The recovery index, time to T1 height > 95% of control, and time to a TOF ratio > 0.9 after sugammadex administration did not differ among the four groups. CONCLUSIONS: Increases in the magnesium concentration in rat PNHD preparations proportionally enhanced the NMB induced by rocuronium but did not affect reversal by equimolar amounts of sugammadex.
Anesthesia
;
Animals
;
Magnesium Sulfate*
;
Magnesium*
;
Neuromuscular Blockade
;
Phrenic Nerve*
;
Rats*
9.Total and ionized serum magnesium and calcium levels during magnesium sulfate administration for preterm labor
Won Hee KIM ; Yoon Ha KIM ; Yuna AN ; Jong Ho MOON ; Eun Ji NOH ; Jong Woon KIM
Obstetrics & Gynecology Science 2018;61(1):56-62
OBJECTIVE: This study aimed to estimate the association between total and ionized magnesium, and the changes in serum magnesium and calcium levels in patients with preterm labor during magnesium sulfate (MgSO4) administration. METHODS: The study population included 64 women who were candidates for intravenous MgSO4 treatment for preterm labor. Serial blood samples were taken and measured total magnesium (T-Mg), ionized magnesium (I-Mg), total calcium (T-Ca), and ionized calcium (I-Ca) levels every one-week interval (1st, 2nd, 3rd). RESULTS: There was no significant difference in T-Mg and I-Mg levels during MgSO4 administration (P>0.05). There was no significant difference in T-Ca and I-Ca levels during MgSO4 administration (P>0.05). Compared before and after administration of MgSO4, T-Mg and I-Mg levels and T-Ca levels were changed allow statistically significant (P < 0.05). But, there was no significant difference in the I-Ca serum levels before and after MgSO4 administration (P=0.495). The I-Mg levels for patients with adverse effect were higher than other group but did not reach statistical significance (P>0.05). There was significant correlation between levels of I-Mg and T-Mg (I-Mg=0.395×T-Mg+0.144, P < 0.01). CONCLUSION: There were no significant differences in serum Mg and Ca levels during MgSO4 administration for preterm labor. Compared to the before and after administration of MgSO4, only I-Ca levels were not substantially changed. There are significant correlations between I-Mg and T-Mg levels during administration of MgSO4 and I-Mg level seemed to have more correlation with adverse effect than T-Mg.
Calcium
;
Female
;
Humans
;
Magnesium Sulfate
;
Magnesium
;
Obstetric Labor, Premature
;
Pregnancy
10.Effects of Magnesium Ascorbyl Phosphate on the Expression of Inflammatory Biomarkers after Treatment of Cultured Sebocytes with Propionibacterium acnes or Ultraviolet B Radiation.
Weon Ju LEE ; Sang Lim KIM ; Kyou Chae LEE ; Mi Yeung SOHN ; Yong Hyun JANG ; Seok Jong LEE ; Do Won KIM
Annals of Dermatology 2016;28(1):129-132
No abstract available.
Biomarkers*
;
Magnesium*
;
Propionibacterium acnes*
;
Propionibacterium*