Objective To analyze the effect of erythropoietin therapy with oral iron supplementation on red blood cell distribution width (RDW)in chronic heart failure patients with anemia.Methods 148 patients of chronic heart failure with anemia from September 2014 to March 2015 in our hospital were included and randomly divided into two groups with the random number table,with 74 cases in each group.The control group were treated with convention-al anti heart failure therapy,the treatment group were treated with erythropoietin and oral iron supplementation on the basis of routine treatment for four weeks.RDW was tested by automatic five classification blood analyzer.The correla-tion between RDW and other detection indexes was analyzed.Results The levels of RDW in the treatment group were significantly lower than those of the control group[(13.08 ±0.792)vs (14.32 ±0.864),t =-8.974,P <0.01].Before treatment,bivariate analysis in the treatment group showed that RDW had positive correlation with NT-proBNP and high -sensitivity C -relative protein (hs -CRP)(r =0.783,P <0.01;r =0.870,P <0.01),but negative correlation with serum creatinine (Cr)and hemoglobin (r =-0.338,P <0.01;r =-0.743,P <0.01).Af-ter treatment,bivariate correlations analysis in the treatment group showed that the difference of RDW was positive correlation with the difference of NT -proBNP,high -sensitivity C -relative protein (hs -CRP)(r =0.783,P <0.01;r =0.680,P <0.01),but negative correlation with the difference of hemoglobin(r =-0.459,P <0.01),and no correlation with the others (Cr,UA,LDL,TC,TG and LVEF).Conclusion On the basis of conventional anti heart failure treatment,erythropoietin therapy with oral iron supplementation against anemia could improve heart func-tion of CHF and decrease the levels of RDW.RDW may be served as one of observing indexes of the worsening and effect judgment in chronic heart failure patients with anemia.

Angioplasty, Balloon, Coronary ; Clinical Trials as Topic ; Humans ; Myocardial Infarction ; drug therapy ; therapy ; Practice Guidelines as Topic

Angina Pectoris ; diagnosis ; therapy ; China ; Guidelines as Topic ; Humans

Angioplasty, Balloon, Coronary ; instrumentation ; Drug Delivery Systems ; instrumentation ; Equipment Safety ; Follow-Up Studies ; Humans ; Stents

Angioplasty, Balloon, Coronary ; Coronary Restenosis ; Humans ; Practice Guidelines as Topic

Angioplasty, Balloon, Coronary ; methods ; Coronary Disease ; therapy ; Coronary Thrombosis ; etiology ; Drug Delivery Systems ; Humans ; Paclitaxel ; administration & dosage ; Sirolimus ; administration & dosage ; Stents ; adverse effects

Angioplasty, Balloon, Coronary ; Coronary Artery Bypass ; Coronary Disease ; therapy ; Guideline Adherence ; Humans ; Practice Guidelines as Topic

OBJECTIVETo provide suggestion for MDAEs monitoring with analyzing the features of the 1028 reports of MDAEs.

METHODSWith retrospective case study, this paper analyzed 1 028 MDAE reports in Guiyang during 2012.

RESULTSThe intrauterine device (IUD) caused the higher proportion of adverse events with serious degree. Monitoring consciousness of grassroots users needs to be improved. The quality of the reports should be enhanced.

CONCLUSIONSMore attention should be paid to monitoring on IUD. The level of MDAEs monitoring should be improved through carrying out targeted training and publicity, establishing and improving MDAEs monitoring network.

Angioplasty, Balloon, Coronary ; Coronary Disease ; therapy ; Humans ; Stents

Humans ; Myocardial Infarction ; physiopathology ; therapy ; Practice Guidelines as Topic