Sudden cardiac arrest is one of the critical clinical syndromes in emergency situations. A cardiopulmonary resuscitation (CPR) is a necessary curing means for those patients with sudden cardiac arrest. In order to simulate effectively the hemodynamic effects of human under AEI-CPR, which is active compression-decompression CPR coupled with enhanced external counter-pulsation and inspiratory impedance threshold valve, and research physiological parameters of each part of lower limbs in more detail, a CPR simulation model established by Babbs was refined. The part of lower limbs was divided into iliac, thigh and calf, which had 15 physiological parameters. Then, these 15 physiological parameters based on genetic algorithm were optimized, and ideal simulation results were obtained finally.
Algorithms ; Cardiopulmonary Resuscitation ; Death, Sudden, Cardiac ; Electric Impedance ; Hemodynamics ; Humans ; Leg ; Models, Cardiovascular

· Mesenchymal stem cells ( MSCs ) are a population of multipotent stem cells with various neurotrophins from bone marrow which are widely used in tissue, cell repair and alternative research.Recently, some researches have shown that MSCs could enhance the viability of neurons under a pathological circumstance by secreting some neurotrophins. So the neuroprotection of MSCs can provide a new method of the treatment on retinopathy that it possible to promote cells survial and functional recovery.Here we make a brief review on the secretory function of neurotrophin and neuroprotective effects of MSCs on retinal cells and its application in the treatment of retinal disease.

Humans ; Immunohistochemistry ; Lymphoma, Large B-Cell, Diffuse ; classification ; pathology

OBJECTIVETo evaluate the clinical efficacy of warming-needle moxibustion on cervical headache.

METHODSSixty-one patients of cervical headache were randomly divided into a warming-needle moxibustion group (30 cases) and an acupuncture group (31 cases). Tianzhu (BL 10), Fengchi (GB 20), Wangu (GB 12), Tianyou (TE 16), Hegu (LI 4), Taichong (LR 3) and Zulinqi (GB 41) were selected in the two groups. Patients in the acupuncture group were treated with acupuncture; patients in the warming-needle moxibustion group were treated with warming-needle moxibustion at Tianzhu (BL 10), Fengchi (GB 20) and Wangu (GB 12) and acupuncture at the remaining acupoints. The treatment was given once every other day, 3 times a week, and totally 4-week treatment was given. The duration and frequency of headache, numerical rating scale (NRS) of headache and cervical range of motion (ROM) were compared before and after treatment in the two groups; also the efficacy of the two groups was evaluated.

RESULTSAfter treatment, the duration and frequency of headache, headache NRS.and cervical ROM score were improved in both groups (all P < 0.05), which were more significant in the warming-needle moxibustion group (all P < 0.05). The total effective rate was 84.3% (25/30) in the warming-needle moxibustion group, which was significantly superior to 61.3% (19/31) in the acupuncture group (P < 0.05).

CONCLUSIONThe warming-needle moxibustion presents significant efficacy on cervical headache, which can obviously improve headache symptoms and cervical ROM.

Acupuncture Points ; Adult ; Cervical Vertebrae ; physiopathology ; Female ; Headache ; etiology ; physiopathology ; therapy ; Humans ; Male ; Middle Aged ; Moxibustion ; Neck Pain ; complications ; physiopathology ; therapy ; Range of Motion, Articular ; Treatment Outcome ; Young Adult

Objective To evaluate the efficacy and safety of nateglinide,a new antidiabetic agent,in the treatment of type 2 diabetes.Methods 276 patients with type 2 diabetes mellitus,in accordance with the table of random number method,were divided into the nateglinide group 138 cases,repaglinide group 138 cases.The nateglinide group was given 30 mg nateglinide,and repaglinide group was given 0.5 mg repaglinide,3 times a day,oral administration 15min before meal.12 weeks for one period of treatment.FBG,2h PBG,HbAlc and security index were detected before and after treatment.Results After treatment,FBG,2h PBG and HbAlc indexes in the two groups were lower than before treatment,the differences were statistically significant(all P ＜ 0.05).The differences were not significant compared between the two groups (all P ＞ 0.05).No serious adverse events occurred in two groups.Conclusion Nateglinide can effectively control fasting and postprandial blood sugar in patients with type 2 diabetes.It is safe and reliable and worthy clinical promotion.

Procalcitonin is a biomarker to diagnose the extent and severity of systemic bacterial infection.Procalcitonin is applied in diagnosis and treatment of systemic inflammatory response syndrome and severe acute pancreatitis.The article reviews application of procalcitonin in clinical surgery and guides use of anti-bacterial agents.

Transjugular intrahepatic portosystemic shunt (TIPS) has been developed for two decades in order to treat portal hypertension accompanying with upper gastrointestinal hemorrhage and refractory ascites.TIPS may cause the development of hepatic encephalopathy (HE).TIPS induces portalsystemic shunt and leads to hemodynamics chaos. Hepatic encephalopathy belongs to the complications of the portal hypertension. There are many possible predictors of the post-TIPS HE. The relationship between TIPS and HE was reviewed.

Objective To study the application value of the cervical cell pathology liquid production technol-ogy in cervical intraepithelial neoplasia (CIN)screening.Methods 4 212 patients were chosen and detected by TCT and the pap staining,TBS (the Bethesda system)to finish thin layer liquid based cytology grading diagnosis,including 558 patients with cervical biopsy,the pathological results were analyzed.Results for histopathological examination results of CIN1,CIN2,CIN3 and cervical cancer cases,a thin layer of liquid based cytology detection rate was 76.00%(57 /75),78.21%(61 /78),95.76%(113 /118),100.00%(7 /7),the comparison between the CIN3 CIN2 group,a thin layer of liquid based cytology detection rate had differences in significant statistical significance (χ2 =14.53,P <0.01),with the histopathological detection of cervical lesions,thin layer of liquid based cytology detection rate was obviously rising trend.Cervical liquid based cytology screening cervical lesion (CIN and above),the sensitiv-ity was 85.61%(238 /278),83.73%(206 /246),positive predictive value 76.28%(238 /312),negative predictive value 72.79%(206 /283).Conclusion The positive results and histopathological results coincidence rate of using thinprep cytologic test to screening for cervical intraepithelial neoplasia (CIN)is high,the precancerous lesions in screening and prevention has important significance,which is worth clinical promotion.

Objective To translate the English version of Diabetes Continuity of Care Scale (DCCS) into Chinese and to test the reliability and validity of the Chinese version of DCCS in diabetes mellitus patients.Methods Totally 245 patients with diabetes mellitus were recruited and were investigated by the Chinese version of DCCS.Results The internal consistency coefficient of the Chinese version of DCCS ranged from 0.728 to 0.942,which was ＞0.70;split half coefficient r=0.784,and the test-retest was 0.864 while which of each dimension ranged from 0.785 to 0.886.The content validity index was 0.934.Factor analysis got five factors,which explained 76.574％ of the total variance;the factor loading of each item was ＞0.4.Conclusions The Chinese version of DCCS has been proved to be reliable and valid.It can be used as a valid tool for the measurement of continuity of care in patients with diabetes mellitus.

Objective To explore the influence of follow-up by telephone on adherence and quality of life for breast cancer patients with hormonal therapy.Methods Totally 78 breast cancer patients with hormonal therapy were divided into the intervention group (40 cases) and the control group (38 cases).The control group were carried on routine guidance treatment and enjoined regular subsequent visit.The patients in intervention group were carried on the above-mentioned treatment and also receive regular follow-up by telephone.Through the follow-up by telephone we provided guidance for present and will present problems.Adherence for breast cancer patients with hormonal therapy and cancer rehabilitation evaluation system-short form(CARES-SF) were used to investigate the patients' adherence and quality of life six month after the intervention.Then we compared the adherence and quality of life before,six month of the intervention.The changes of adherence and quality of life scores were analyzed by repeated-measure ANOVA.Results The score of quality of life in the intervention group after 6 month of intervention was (25.43 ± 6.04),while in the control group was (40.61 ± 7.73),the difference was significant between the two groups,P＜0.05.The score of medication adherence in the intervention group after 6 month of intervention was (8.57 ± 6.20),while in the control group was (14.12 ± 6.63),the difference was significant between the two groups,P＜0.05.Conclusion Follow-up by telephone can improve adherence and quality of life for breast cancer patients with hormonal therapy.