Critical Illness ; therapy ; Humans ; Nutritional Support

Program monitoring and evaluation (M & E) is the major method used in the international collaboration programs on disease control and prevention in China in recent years. It functions in the progress overseeing,problem finding and solving in terms of enhancing the program quality,managing the work plan,summing up the experiences,auditing the performance and finally achieving the expected goal. The indicators and implementation progress based on M & E serve as a scientific tool to measure the program implementation outcome periodically.

Objective To analyze the relationship between volume,conductivity,laser light scatter (VCS) of lymphocytes and monocytes and atypical lymphocyte.Methods The clinical data of 129 patients with virus infection and 50 healthy controls received blood routine examination by Sysmex-800i hematology analyzer in our hospital were retrospectively analyzed.The lymphocyte volume (MLV),distribution width,(LDW),conductance rate (MLC),laser scattering(MLS) and monocyte cell volume (MMV),distribution width,(MDW),electrical conductivity (MMC),laser scattering(MMS) were analyzed.And according to the heterotypic lymphocyte ratio,the virus infection patients were divided into group 1 (abnormal rate 2％-5％),group 2 (abnormal rate ＞ 5％-10％),group 3 (abnormal rate ＞10％).The healthy controls were selected as control group.The VCS parameters of the four groups were compared.Results The LDW of group 1 was (17.2 ± 2.5) FL,that of the control group was (14.1 ± 2.7) FL,the difference was statistically significant(t =2.362,P ＜0.05).The MLV,LDW,MMV,MDW of group 2 were (85.3 ±5.6) ×109/L,(19 ±3.1) FL,(185.9 ±9.2) × 109/L,(22 ±2.9) FL,which were significantly higher than those of the control group (t =2.557,3.086,2.735,4.269,P ＜ 0.05).The MLV,LDW,MMV,MDW of group 3 were (89.5 ±6.8) ×109/L,(22.3 ±3.6) FL,(194.5 ±9.6) ×109/L,(24.5 ±3.4) FL,which were significantly higher than those in the control group (t =2.982,3.569,2.945,4.863,P ＜ 0.05).The MLC,MLS,MMC,MMS of group 1 were (112.3 ±7.8) μs/cm,(54.8 ±4.9) NTU,(112.3 ±7.8)μs/cm,(83.6 ±4.7) NTU,those in group 2 were (104.7 ±6.9)μs/cm,(52.6 ± 4.5) NTU,(104.7 ± 6.9) μs/cm; (81.1 ± 4.3) NTU,those in group 3 were (96.5 ± 6.2) μs/cm,(50.5 ± 4.3) NTU,(96.5 ± 6.2) μs/cm,(78.7 ± 3.8) NTU,those in the three groups were significantly lower than in the control group (t =2.623,3.195,2.247,5.829,2.457,2.956,2.371,6.715,2.573,3.044,4.395,7.386,P ＜ 0.05).Conclusion VCS parameters of lymphocytes and mononuclear cells of two types of white blood cells can reflect to a certain extent,peripheral blood heterotypic lymphocyte morphology changes of clinical infection,has the reference value of diagnosis and treatment of disease.

Gait problems in cerebral palsy patients are usually caused by spasticity or contracture of two joints muscles,and the imbalance between synergic muscles and antagonistic muscles. The knee problems are the most common seen in cerebral palsy patients. The paper discusses the common abnormalities of the knee in cere-bral palsy and the development in treatment of the deformities.

Objective To investigate the indications and clinical values of percutaneous transthoracic biopsy guided by different locating means respectively on pulmonary lesions. Methods Patients were divided into different groups according the locating methods,which included X -ray, type -B ultrasonography, and CT. Pathologic diagnosis and complications were retrospectively analysed between groups. Conclusion Each locating method has its own advantages and disadvantages. Results we should choose the optimistic one according the patients′ condition.

The responsibility system of attending doctors plays a positive role in raising hospital efficiency and optimizing medical resources deployment.For the change in the subject of medical liabilities following the introduction of this system,medical management needs to shift from department management to doctor management instead.In the meantime,appropriate rules and regulations are needed to normalize the roles and behavior of the medical office,department heads,and attending doctors in medical activities.This will ensure the successful operation of this responsibility system,and generate ideal medical,economic and social outcomes.

OBJECTIVE:To evaluate the status quo and tendency of the use of Chinese material medical injection(CMMI) in Nanjing area.METHOD:Chinese material medica injection used in 22 hospital of Nanjing from 2004 to 2006 was analyzed statistically in terms of variety,consumption sum,defined daily dose(DDDs) etc. RESULTS: The consumption sum of CMMI increased year by year,with annual incremental rates of 19.80% and 11.82% respectively.The cardio-cerebral vascular CMMI dominated the first place in terms of consumption sum and DDDs over the 3 years.Lentinan,Shengmai,Shenmai,Puerarin took the lead in consumption sum of single variety.The variety and specification and the number of manufacturers of CMMI increased year by year.CONCLUSION:CMMI plays a key role in clinical treatment,its consumption sum and consumption quantity kept increasing rapidly.

Spastic diplegia and hemiplegia are the common types of cerebral palsy which needs treat-ment in clinic. The paper discusses the classification of gait problems in these two types of cerebral palsy and ac-cording to gait analysis,recommended the management for them. Through the understanding of the classification, the treatment plan could be made individually regarding the GMFCS level of the patient and improve their functions.

AIM:To evaluate the efficacy of Wuling Capsule(xylaria) in treating senile systolic hypertension. METHODS: Sixty-four patients with senile systolic hypertension were randomly divided into two groups.Both the treated group and the control group were treated with anti-hypertensive for 4 weeks,but the treated group received Wuling Capsule.Therapentic effects were evaluated with HAMA.Noninvasive resting blood pressure was taken every day after treatment,and dynamic blood pressure before and after treatment. RESULTS: HAMA in both groups decreased somewhat but blood pressure in the treated group was lower than that in the control group,remission rate of the treated group was greater than that in the control group.Treatment period of the treated group was shorter than that of the control group. CONCLUSION: Wuling Capsule can relief anxiety in senile hypertension patients,and it can rise the control rate of blood pressure,and also shorten the treatment period.

Objective To optimize the formulation of controlled-onset extended-release tablets of nicorandilby central composite design-response surface method. Methods The tablets containing nicorandil were prepared bydry-compression coating technique.The influence factors included the amount of HPMC, the amount of EC, and the ratio of lactose/MCC in coating film. The evaluation parameter was Q4 h and Q5 h . The possibly optimal formulation was predicted by response surface method. Results The OD was simulated using second-order polynomial equation and the r2was 0.970 1.Optimal prescription was as follows:HPMC 89.96 mg, EC 46.21 mg, Lactose/MCC 1.87.Bias between the observed and predicted values of the OD was within 0.43%. Conclusion The controlled-onset extended-release tablets of nicorandil can release drug quickly in vitro at the predetermined time.Central composite design-response surface method can be used to optimize the formulation and the model developed in this study was proved highly predictable.