OBJECTIVE:To observe clinical efficacy and safety of Autoserum eye drops in the treatment of filamentary kerati-tis after excimer laser corneal refractive surgery. METHODS:46 patients (90 eyes) with filamentary keratitis after excimer laser corneal refractive surgery were selected and randomly divided into control group and observation group with 23 cases(45 eyes)in each group. The control group was given clearing mesh+wearing soft contact lens+bFGF eye drops;the observation group was giv-en clearing mesh+ wearing soft contact lens + Autoserum eye drops. The clinical efficacy,cure time,recurrence rate and ADR were compared between 2 groups. RESULTS:The total effective rate of observation group was 93.3%,which was higher than that (82.2%)of the control group,with statistical significance(P<0.05);the cure time of observation group was(2.7±1.1)d,which was shortened significantly compared with control group [(3.5±1.2)d],with statistical significance(P<0.05). The recurrence rate of filamentous keratitis was 4.4% in observation group and 15.6% in control group;the observation group was significantly lower than the control group,with statistical significance(P<0.05). During the treatment,there were 1 case(1 eyes)of corneal epitheli-al edema in observation group and 2 cases (2 eyes) of corneal epithelial edema in control group,there was no statistical signifi-cance(P>0.05). CONCLUSIONS:In the treatment of filamentous keratitis after excimer laser corneal refractive surgery,therapy of clearing mesh+wearing soft contact lens+Autoserum eye drops have high total effective rate,low recurrence rate and short cure period with less ADR.

The test procedure and content of valves pressure test of AK95 hemodialysis machine are mainly introduced.The valves pressure test are the key of the self test procedure in hemsdialysis machine.It is necessary to find the accurate process where problems occur.[Chinese Medical Equipment Journal,2008,29(2):94]

The BM self-test of GAMBRO AK95 hemodialysis machine is introduced, including venous pressure test, arterial pressure test, priming detector test, blood pump test, venous clamp test, arterial clamp test, air detector test, high venous pressure test, etc. The detail introduction of high venous pressure test is of great benefit to solve some faults of hemodialysis machine.

The self-learning and self-check system of medical immunology has been established by online Active Server Pages(ASP) technique.The students’learning results can be examined and evaluated automatically by the system.The students can freely choose the parameters of grouping up test-papers,according to their different situation,which is more rational and the test result is closer to students’true achievement.After the test is finished,the system can check the answers automatically and show the test-score.Through the humanized test design and the feedback encouraging teaching mode,the system affords fine conditions for independent learning of medical students and solves the problems of the combination between teachers’teaching and learners’ practicing.

With the development of computing and storage techniques,there are a lot of medical records and clinical data stored.It raises the issue of how to mine knowledge from these records and to promote the development of traditional Chinese medicine (TCM).Several challenging research subjects of Chinese clinical medicine data mining and analysis have been introduced in the framework of disease-symptom-syndrome-formulaeffect,and the corresponding developments have also been reported.The significant meaning of the data mining and analysis to Chinese medicine is discussed.Then,the detailed works and recent achievements of seven subjects are given including:① Analysis of symptoms to obtain the optimal symptom subset for one disease or syndrome.② Symptom-syndrome or disease to obtain models for syndrome differentiation.③ Analysis of syndrome.④Analysis of Core formula as well as drug addition and subtraction.⑤ Formula-symptom-effect.⑥ Computerized symptoms.⑦ TCM knowledge engineering.

Objective To analyze the correlation between the UK National Early Warning Score (NEWS) and emergency elderly patients within six hours' outcomes,study the value of NEWS in the prescreening assessment of elderly patients.Methods 213 cases of emergency elderly patients were selected as a sample,and were evaluated with NEWS pre-check.Then we tracked patients' outcomes within six hours were analyzed the correlation between the two.Results With NEWS score increased,the salvage rate and fatality rate were increased.Conclusions NEWS shows independent predictive value in the pre-screening assessment of the emergency system,and should be widely applied in it.

Objective: To study the effects of the different doses of midazolam in fibreoptic gastroscopy on sedation, respiratory and circulatory function. Method: One hundred and four outpatients undergoing fibreoptic gastroscopy were randomly divided into four groups. The control group(N)was not given drugs, the other groups were intravenously given midazolam 0.07mg/kg(MS),0.05mg/kg(M),diazepam 10mg(D)respectively. The sedative scores, symptom, amnesia,HR,MAP and blood gases were observed. Result: The sedative scores of MS,M and D groups were much better than that of control group. There were significant differences in sedative scores,amnesia and sedative period between MS group and D group or M group. MAP decreased one minute after administering the drugs in MS,D and M groups significantly. The results of blood gases analysis of all groups were in normal ranges. Conclusion: Midazolam 0.07mg/kg can produce safe and effective sedation for fibreoptic gastroscopy.

Unilateral neglect is one of the common advanced neurological deficits of stroke. This article highlights the post-stroke definition of unilateral neglect, incidence, sites of lesion resulting in neglect, possible mechanisms and clinical manifestation. It overviews the typing and complications of unilateral neglect, and points out that the significance on the assessment and treatment of unilateral neglect.

Objective To compare and analyze differences in clinical characteristics, auxiliary examination and im?munotherapy between children with anti-N-methyl-D-aspartate(NMDA) receptor encephalitis and adults. Methods Clinical data was retrospectively collected from 34 cases anti-NMDA receptor encephalitis. All people were divided into the child group and the adult according to the age of onset and the inpatient department. Score of Modified Rankin Scale (mRS) before and after treatment and follow-up period (6 months~24 months) were compared to estimate the neurologi?cal outcomes. Results Data from 34 patients including 19 children and 15 adults was analyzed. Hypoventilation, epilep?sy and status epilepticus were more common in the adult group than in the child. The positive rate of EEG delta brush was higher in child group than in adult group. Two women were complicated by suspicious ovarian teratoma. Intravenous immune globulin was used commonly in the child group, while the plasma exchange or immunosuppressant used common?ly in the adult group. Time of onset to hospital admission and final diagnosis were shorter in the child group than in the adult. Patients requiring ICU were fewer in the child group than in the adult. The scores of mRS were significantly lower in the child group than in the adult at hospital discharge (P<0.05). Conclusion Clinical characteristics is more compli?cated in adults with anti-NMDA receptor encephalitis compared with children including a worse disease severity and a poorer short-term outcome.

OBJECTIVE:To find out the situation of the use of antimicrobials in perioperative patients and to evaluate the rationality of use.METHODS: To make a survey of the use of antimicrobials in 230 surgical patients during the period Dec. 2002 - Apr. 2004, and to evaluate the kinds, frequency, cost - effectiveness ratios, combined administration, course, effectiveness and drug adverse react ions. RESULTS: 100 percent patients had received antimicrobials involving 32 kinds of drug and 8 595 case - time.The cost of consumption of antimicrobials per case was 1 183.5 yuans.The average therapeutic course was 21.89 days.The operation incisions healed by first intention in 230 cases.The cost ratios of total drugs and antimicrobials was 1 : 0.41 .CONCLUSION:The supervision of using antimicrobials in perioperative period must be reinforced.