Objective To explore the clinical application of anticoagulation therapy for patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods 55 patients with AECOPD were selected and divided into control group(24 cases) and treatment group(31 cases).Oxygen treatment,anti-infection treatment were applied to the patients of the control group.Treatment group was given anticoagulation treatment with heparin at the base treatment of the control group.The treatment efficacy,pulmonary functions,coagulation functions and inflammatory factors were tested and compared.Results There were no significant differences between two groups of total treatment efficacy(80.65％ vs 79.17％,x2 =1.304,P ＞0.05) ;PaCO2 decreased,pH and PaO2 increased significantly after treatments in the two groups(all P ＜ 0.05),which was more significantly in the treatment group (all P ＜0.05) ;FVC,FEV1 and FEV1/ FVC％ increased significantly after treatments in the two groups(all P ＜ 0.05),more significantly in the treatment group (all P ＜ 0.05) ; APTT,PT were prolonged,the level of DD and PAD decreased significantly after treatments in the two groups(all P ＜ 0.05),which was more significantly in the treatment group(all P ＜ 0.05) ;The level of IL-6,IL-10 and hs-CRP decreased significantly in all patients(all P ＜ 0.05),IL-6and hs-CRP were more significantly in the treatment group (all P ＜ 0.05),but the level of IL-10 of the treatment group was higher than that of the control group (P ＜ 0.05).Conclusion Pulmonary functions,Blood-gas indexes could be improved,inflammatory balance and coagulation status could be maintained by anti-coagulation treatment in patients with AECOPD.

Objective To study the prevention of pressure ulcer for bed-ridden patients by simple turn-over pillow and turn-over mattress.Methods Self-made simple turn-over pillow and turnover mattress were used in 1300 patients who had high risk of pressure ulcer,and the application effect was observed.Results No pressure ulcer occurred in 1300 patients when they were discharged.Conclusions Simple turn-over pillow and turn-over mattress showed definite effect to prevent pressure ulcer,they have application value,and are worthy of wide spread.

Objective To study the possibility and effect of application of clinical pathways (CP) in patients with lumbar vertebrae protrusion undergoing resection of nucleus pulposus. Methods 280 patients with lumbar vertebrae protrusion undergoing resection of nucleus pulposus were selected and divided into the experimental group and the control group randomly. Each group had 140 cases. Clinical pathways was applied to the experimental group, while traditional nursing method was given to the control group. Treatment and nursing effect were compared between the two groups. Results The cost for hospitalization was lower, hospitalization time was shorter, the first time for functional exercise after operation was advanced and satisfaction degree of patients was increased in the experimental group compared with those of the control group. Conclusions Application of clinical pathway in patients with lumbar vertebrae protrusion undergoing resection of nucleus pulposus played a positive and effective role.

Objective:To investigate the effects of endoscopic local treatment for colorectal intramucosal carcinoma.Methods:42 patients with colorectal intramucosal carcinoma were treated with endoscopic local through one or few methods such as biopsy forceps resection,looping ligature and high frequency electric coagulation etc.in past five years.Results:(1)18 cases received biopsy forceps resection,3 cases received looping ligature,16cases received high frequency electric coagulatio resection,5 cases received many kinds of methods.(2)3 cases of 5 cases with advanced carcinoma were operated enlarge radical surgery except 1 cases who refused operation and 1 cases who losted operation opportunity.In the rest 37 cases,7cases were operated surgery,malignant remnants were no founded in theses colon specimens.(3)The following-up 33cases(30 cases without surgery)failed to show recurrent cancer for 1 month to 5 years.(4)In the following-up cases,the incidence of neogenesis adenoma was 57.1% in cancer with pilosity adenoma and was 15.8% in early cancer without adenoma during 1 year to 3 years after operation.Conclusions:It can achieve to healing,security and minimum invasive treatment for endoscopic local resection to colorectal intramucosal carcinoma as long as it is suitable to select case.

Objective:To evaluate the influence of health education on knowledge and attitude about drugs and addictive drug abuse prevention among the junior middle school students.Methods:389 junior middle school students were selected in this program.Drugs and addictive drug abuse prevention related knowledge and attitude of the junior middle school students were surveyed by questionnaire anonymously before and after the health education.Results:After education,average score of drugs and addictive drug abuse prevention knowledge among the junior middle school students was significantly increased from 8.8 to 15.7(full score 17),suggesting the significant difference.The junior middle school student's level of knowledge about the danger of smoking and drinking also increased significantly.The correct rate of the answers rose from 4.6%～78.6% to 79.4%～100.0%.After this education,the rate of correct attitude about the drugs and addictive drug abuse prevention was significantly higher than before.Conclusion:The study suggests that health education on drugs and addictive drug abuse prevention among the junior middle school students has the positive impact on increasing the basic knowledge on the drugs and addictive drug abuse prevention for the junior middle school students as well as setting up the correct attitude on it.

Objective:To assess the anatomy of portal vein and hepatic vein with three dimensional 16-MSCT angiography.Methods:A total of 100 healthy subjects underwent upper abdominal MSCT examinations in our department.All subjects were administered 90～120ml of IV contrast material at an injection rate of 3ml/s.The scan delay time was 45～60s and 90～120s for portal venous and hepatic venous phase with automated bolus tracking,respectively.All data sets were reconstructed in 1-mm section and 0.5mm interval,and then were transferred to a workstation for maximum intensity projection(MIP)and volume ren-dering(VR) econstruction.The portal vein anatomy was classified according to Couinaud and Atri’s classification;the hepatic veinanatomy according to Nakamura’s,Marcos’s and Kawasaki’s classification.Results:① Normal portal vein anatomy was seen in 76 cases,type Ⅱin 16,type Ⅲ in 6,type Ⅳ in 2.②Nakamura’s TypeⅠof hepatic vein was presented in 72 cases;type Ⅱ in 22.type Ⅲ in 6.The branching pattern of the middle hepatic vein was type Ⅰin 65 cases,type Ⅱin 19,and type Ⅲ in 16.Segment IVb vein branched from the middle hepatic vein in 42 cases,and from the left hepatic vein in 58.Conclusion:3D 16-MSCTA is a significantly valuable tool which can provide complete and comprehensive information on the anatomy of portal vein and hepatic vein combined with MIP and VR image.

To introduce the academic thoughts of traditional Chinese medicine(TCM)master GUO Zi-guang based on the analysis of clinical cases.His main academic thoughts are:①He proposes the theory of six meridians and their differentiation in the diagnosis and treatment of typhoid.The six meridians are bases for the treatment of all diseases,and their differentiation provides a fundamental principle for the differentiation of diseases.②He uses the method of combining the disease and syndrome in diagnosis and treatment,which widens the horizon of traditional differentiation and diagnosis in TCM and avoids the absence of syndrome in the practice of differentiation.In this way,the therapeutic effects of Chinese medicine can be guaranteed so as to meet the needs of medical and social development.③He emphasizes that it is fundamental to improve the therapeutic effects of TCM for its development.The approach is to combine disease and syndrome in diagnosis and treatment,and the way is to apply different methods in disease treatment.

Pelvic congestion syndrome plagues women's physical and mental health,the morbidity rate has increased in recent years.Based on TCM differentiation and classifications of syndrome,pathogenesis of pelvic congestion syndrome is divided into‘dampness-blood stasis’and‘deficiency of qi resulting blood stasis’2 types.Our Qushi Huayu Decoction and Yiqi Tongyu Decoction have been clinically proven to relieve pain,improve quality of life of the patients,and achieve better clinical effect.

Objective To compare of treatment effects of intravenous iron and oral iron on hemodialysis ane- mia in patients with erythropoietin.Methods The oral dosage of ferrous succinate was 200mg dose,3 times a day for 2 months.After washing out for 2 months.Then these patients were given intravenous iron dextran with a dosage of 100mg twice a week for 5 weeks.During the treatment,hemoglobin (Hb),hematocrit (Hct),serum ferritin (SF) and trasferrin saturation(TSAT) were monitored.Results The efficacy of oral iron was 20 % ,the efficacy of intra- venous iron was 60 %.The Hb,Hct,SF and TSATS level increased obviously in the efficacy of intravenous iron,sta- tistical analysis showed a very significant difference(P

Objective:To culture mesenchymal progenitor cells(MPC)from compact bone fragments in C57 mice in vitro and to study the feasibility of inducing directed differentiation of MPC into neuron-like cells in vitro. Methods:Bones of hind limbs of C57 mice were sheared into bone fragments and digested by collagenase type Ⅱ. Then,MPC were cultured in vitro and analyzed by flow cytometry for identification of its immunology phenotype. MPC of P3 in good growth were induced directionally by the supernatant cultured with primary neuron,and then detected the expression of neuronal specific markers neuron specific enolase(NSE)and neurofilament protein(NF)by immunocytochemical staining. Results:The primary MPC were cultured successfully and they grewwell after passage. Compared with that of the control group,the positive rate of CD29 and CD44 of MPC of antibody group had significant difference (P