2.Myogenic sarcoma of pulmonary vein: report of a case.
Tao ZHU ; Zhi-nong JIANG ; Mei JIN
Chinese Journal of Pathology 2011;40(5):346-347
Adult
;
Desmin
;
metabolism
;
Diagnosis, Differential
;
Female
;
Heart Neoplasms
;
pathology
;
Humans
;
Myxoma
;
pathology
;
Ovarian Neoplasms
;
secondary
;
surgery
;
Pulmonary Veins
;
Sarcoma
;
diagnostic imaging
;
metabolism
;
pathology
;
secondary
;
surgery
;
Tomography, X-Ray Computed
;
Vascular Neoplasms
;
diagnostic imaging
;
metabolism
;
pathology
;
surgery
;
Vimentin
;
metabolism
3.The clinical characteristics of colorectal cancer in Guangdong province
An-Gao XU ; Bo JIANG ; Zhi-Jin YU ;
Chinese Journal of Digestion 2001;0(07):-
Objective To investigate the clinical characteristics of colorectal cancer and its trend in Guangdong province.Methods The data from 6501 patients with pathologically confirmed colorectal cancer of 5 hospitals from 1990 to 2004 was analyzed.Results The mean age of 6501 patients with colo- rectal cancer was 59 years old,with the predominant age ranged from 61 to 70 years old.The proportion of young patients decreased from 7.1% to 3.5%.and the ratio between male and female was 1.47:1, which was gradually increased with increasing of age.The prevelence reached a high peak(60 years old) and dropped after that as a single peak curve.The ratio between rectal cancer and colon cancer was 1.1: 1,and the descending colon cancer accounted for 27.6%.With ageing,the rectal cancers decreased while the right hemi colon cancer increased gradually.Tubular adenocarinoma was predominant with his- tological typing,which accounted for 76.0%.The progressing stage(Dukes B,C,and D)was found in 93.9% of all cases.Conclusions The onset age of patients with colorectal cancer become close to west- ern country.The proportion of young patients are decreasing.The ratio between male and female dis- plays a single peak curve from rising to dropping.A tendency of decreasing percentage in rectal cancer and the gradual increasing in right hemi colon cancer emphasize the importance of colonoscopy in colorec- tal caner screening.
4.Primary hemangiopericytoma of bone: report of a case.
Zhi-ming JIANG ; Hui-zhen ZHANG ; Jin HUANG ; Juan ZHOU
Chinese Journal of Pathology 2012;41(2):139-139
Adolescent
;
Antigens, CD34
;
metabolism
;
Bone Neoplasms
;
diagnostic imaging
;
metabolism
;
pathology
;
Chondrosarcoma, Mesenchymal
;
metabolism
;
pathology
;
Diagnosis, Differential
;
Hemangiopericytoma
;
diagnostic imaging
;
metabolism
;
pathology
;
Humans
;
Male
;
Platelet Endothelial Cell Adhesion Molecule-1
;
metabolism
;
Sarcoma, Synovial
;
metabolism
;
pathology
;
Tomography, X-Ray Computed
;
Vimentin
;
metabolism
5.Lymphoepithelial carcinoma of renal pelvis: report of a case.
Chinese Journal of Pathology 2010;39(11):772-773
Carcinoma, Squamous Cell
;
metabolism
;
pathology
;
surgery
;
Female
;
Follow-Up Studies
;
Humans
;
Keratin-7
;
metabolism
;
Keratins
;
metabolism
;
Kidney Neoplasms
;
metabolism
;
pathology
;
surgery
;
Kidney Pelvis
;
Middle Aged
;
Mucin-1
;
metabolism
8.Inhibition effect of 6-gingerol on hair growth.
Yong MIAO ; Ya-Bin SUN ; Wen-Jun WANG ; Zhi-Dan ZHANG ; Jin-Dou JIANG ; Ze-Hua LI ; Zhi-Qi HU
Chinese Journal of Plastic Surgery 2013;29(6):448-452
OBJECTIVETo investigate the effect of 6-gingerol, the main active component of ginger, on hair shaft elongation in vitro and hair growth in vivo.
METHODSFirstly, Hair follicles were co-cultured with 3 different concentration of 6-gingerol for 5 days and hair elongation in three groups was measured. Secondly, The proliferative effect of 6-gingerol on DPCs was measured using MTT assay. Thirdly, the expression of Bcl-2 and Bax in DPCs were measured using Western blotting. In vivo study, the influence of 6-gingerol on hair growth in C57BL/6 rats was measured through topical application of 6-gingerol on the dorsal skin of each animal.
RESULTSThe length of hair shaft in 20 microg/ml 6-Gingerol group (0.50 +/- 0.08 mm) is less than 0 microg/ml (0.66 +/- 0.19) mm and 10 microg/ml (0.64 +/- 0.03) mm 6-Gingerol group (P < 0.05). In cell culture, compared to 0 microg/ml and 5 microg/ml 6-Gingerol, 10 microg/ml 6-Gingerol can significantly inhibited the proliferation of DPCs (P < 0.05). Along with the growth inhibition of DPCs by 6-gingerol, the Bax/Bcl-2 ratio increased obviously. In vivo study, the hair length and density decreased a lot after using 1 mg/ml 6-gingerol.
CONCLUSIONS6-Gingerol can suppress human hair shaft elongation because it has pro-apoptotic effects on DPCs via increasing Bax/Bcl-2 ratio. It might inhibit hair growth by prolonging the telogen stage in vivo.
Animals ; Catechols ; pharmacology ; Cell Culture Techniques ; Cells, Cultured ; Fatty Alcohols ; pharmacology ; Hair ; drug effects ; growth & development ; Hair Follicle ; drug effects ; growth & development ; Humans ; Mice ; Mice, Inbred C57BL ; Plant Extracts ; pharmacology ; Rats ; bcl-2-Associated X Protein ; metabolism