Dental Offices ; Hospitals ; Noise, Occupational

Acquired Immunodeficiency Syndrome ; prevention & control ; Dental Staff ; Humans ; Occupational Exposure ; prevention & control

Objective To investigate and compare the clinical efficacy of mifepristone alone and combined with Gongliuxiao capsule in the treatment of uterine fibroids.Methods 106 patients with uterine fibroids in Harrison International Peace Hospital from December 2012 to December 2013 were selected.The patients were randomly divided into control group and experimental group(n=53).The former were treated with mifepristone alone while the later were treated with the combination of mifepristone and Gongliuxiao capsule.All the patients were given 2 courses of treatment with 12 weeks for a course.The menstrual phase,volume of menstruation,uterus and the volorne of uterine fibroids before and after the treatment,and the clinical efficacy of both groups were evaluated.All the results were recorded and compared. Results The menstrual phase,volume of menstruation,uterus and uterine fibroids of both groups after the treatment were significantly less than those before treatment (P <0.05 ).And the total effective rate of experimental group was 92.45%,which was significantly higher than 73.58% of control group.Both groups had some mild adverse reactions,which didn’t affect the treatment.Conclusion The combination of mifepristone and Gongliuxiao capsule has a great efficacy in the treatment of uterine fibroids.Compared with the use of mifepristone alone,the combination treatment is much more effective.

Objective To evaluate the effect of combination of phacoemulsification and trabeculectomy on patients with cataract and glaucoma.Methods 19 patients(23 eyes)with co-existing glaucoma and cataract were treated with triple procedure by means of scleral tunnel flap.The mean follow-up period was(15.8 ±3.5)months.Results Compared with preoperative visual acuity,16(64%)of 25 eyes had a best corrected visual acuity of ≥0.6 at the last follow-up(0.1～1.0)(P＜0.01);The mean preoperative intraocular pressure(IOP)was(23.01 ±2.63)mmHg which decreased to(14.02 ±2.05)mmHg(P＜0.05 ,P ＜0.01)after treatment.Conclusion The triple procedure is effective for treating patients with co-existing cataract and glaucoma,which could enhance the visual acuity,control IOP and reduce complications.

After major operation,a series of complicated pathological and physiological changes will occur during the trauma and stress state.The protein synthesis is affected,which results in negative nitrogen balance.In addition,the release of inflammatory factors can damage the capillary endothelial cells and increase the permeability of micrangium,induce vascular colloidal albumin leakage to the extravascular tissue,decrease plasma albumin,make wound edema,eventually lead to postoperative hypoproteinemia.Except for albumin supplement,it should be aimed at the mechanism to control the stress response and reduce the leakage caused by the release of inflammatory factors to solve this problem radically in clinical work.The reports about the causes and treatment of hypoproteinemia after major surgery were reviewed to provide evidence for clinical treatment.

Objective To observe and compare anatomical position between pediatric internal jugular vein and common carotid artery in children patients of different ages with ultrasonic technique.Methods Four hundred and ninety-six cases of pediatric patients undergoing selective operation,ASA physical status Ⅰ or Ⅱ,were selected in this study,they were 380 males and 116 females ranging from 0 to 12 years.Image position of internal jugular vein and common carotid artery above the clavicle were detected with ultrasonic technique for all pediatric patients,positions of internal jugular vein and common carotid artery for different patients were classified according to different angles,anatomical position between pediatric internal jugular vein and common carotid artery in different age groups (newborn group,infant group,toddler group,preschool children group and school-age children group) were compared.Results In area between 0°-30°,the ratios of right puncture of infant group,toddler group,preschool children group and school-age children group were significantly higher than those of the left (infant group: 42.3% vs 0%;toddler group: 48.8% vs 1.6%;preschool children group: 57.5% vs 2.7%;school-age children group: 58.0% vs 2.1%)(P<0.01).In area between 30°-60°,the ratios of the right puncture in all groups were significantly higher than those of the left (newborn group: 45.0% vs 10%;infant group: 44.2% vs 23.1%;toddler group: 46.3% vs 19.5%;preschool children group: 35.4% vs 19.5%;school-age children group: 35.1% vs 20.2%) (P<0.05 or P<0.01).In areas between 60°-90°and at 90°,the ratios of the right puncture in infant group,young children group,preschool children group and school-age children group were significantly higher than those of the left (P<0.01).In areas of >90°,there was no statistical difference between the ratios of the right puncture and the left in all groups.Conclusion The success rate of right internal jugular vein puncture of children was higher than that of the left.Conditions in the newborn group were different from that in the other age groups.

Objective To observe the effect of two different methods of fixed temporary pacemaker electrode. Methods Fromn April 2015 to December 80 temporary pacemaker patients were randomly divided into control group (n = 40) and the experimental group (n = 40), the control group using gauze cloth tape cross method combined with the traditional fixed, the experimental group was treated with 3M type of comfortable and stable transparent dressing+3M pressure fixing belt fixed, to compare two groups in the skin lesions, electrode dislocation, inflammatory reaction, the switching frequency difference. Results There was no significant difference between the two groups in general data (P>0.05). There was no significant difference between the two groups in the cost of dressing and materials、electrode dislocation (P>0.05), experimental group of the switching frequency is lower than the control group (Z=-2.064, P<0.05), the differences were statistically significant. Conclusions 3M comfortable type solid transparent sticking and 3M pressurized fixed band method in the absence of increased medical costs while ensuring medical safety, save the manpower cost.

Japanese kampo medicine originated from traditional Chinese medicine. But different from TCM pattern of "Tracing the etiology by syndrome differentiation-establishing therapeutic methods-prescribing formula", during the process of development, Japanese kampo medicine has gradually formed a different diagnostic and therapeutic mode, which was "corresponding prescription and pattern". This therapeutic mode directly chose formula from ancient books, especially Shanghanlun (Treatise on Febrile Diseases), according to the constitution, symptoms and signs of patients. The diagnostic and therapeutic mode of Japanese kampo medicine provides references for integration of traditional Chinese and western medicine.

Objective: To investigate the effect of short hairpin RNA (shRNA)-targeting special ATrich sequence-binding protein-1 (SATB 1) on the apoptosis of human lung cancer cell line A549, and to explore the possible mechanism. Methods: The recombined plasmid SATB1-shRNA of shRNA-targeting SATB 1 was constructed and transfected into A549 cells by LipofectAMINE 2000. The expression levels of SATB1, Bcl-2 and Bax mRNAs were examined by RT-PCR, and the expression levels of SATB1, Bcl-2, Bax, and caspase 3 proteins were examined by Western-blotting. The apoptosis rate of A549 cells was detected by flow cytometry (FCM). Results: The recombined plasmid SATB1-shRNA was successfully constructed and transfected into the A549 cells. After transfection with SATB1-shRNA, the expression levels of SATB1 and Bcl-2 mRNAs and proteins were decreased (P <0.05), whereas the expression levels of Bax mRNA and protein and the caspase 3 protein were increased (P <0.05). The apoptosis rate of A549 cells after transfection with SATB1-shRNA was higher than that of the A549 cells without transfection with SATB1-shRNA [(14.18±1.59) % vs (1.84±0.57) %, P <0.01]. Conclusion: SATB1-shRNA can significantly down-regulate the expression level of SATB1 in human lung cancer cell line A549 and induce the apoptosis. The mechanism may be related to the cascade effect induced by the down-regulation of Bcl-2 expression. Copyright © 2012 by TUMOR.

Objective To study the effects of antidepressant treatment on living quality of patients at stable stage of COPD with depression. Methods 43 cases at stable stage of COPD with depression were randomly divided into treatment group( n = 22) and control group( n = 21 ). The control group were given appropriate bronchodilators and disperse phlegm with common;the treatment group were given zoleft(50mg, 1 time/d, 6 weeks and 10 weeks) based on the control group. Lung function, nutritional status and quality of life score before and after inpatient treat-ment were determined. Results There was significant difference on lung function, nutritional status and quality of life score between the treatment group before and after inpatient treatment( P < 0.05 ～ P < 0.01 ). There was no significant difference in the control group (P > 0.05 ). Conclusion Antidepressant treatment on patients at stable stage of COPD with depression is very important for improving the quality of life.