Short stature is diagnosed according to the person below the normal height of mean -2 standard de-viation or below the third percentile,respectively,of the same race,age,and sex.Diagnosis needs comprehensive assess-ment,including detailed medical history collection,detailed physical examination and appropriate laboratory tests.There are limitations of these factors in diagnosing the reasons of short stature,but the rapid progress on genomics and techno-logy enriched the diagnostic methods.Ongoing research efforts to identify genes influencing growth will provide a better understanding of mechanisms underlying abnormal growth and will eventually lead to novel management approaches.

Objective To observe the effect of Auto-CPAP in the treatment of patients with obstructive sleep apnea-hypopnea syndrome,to sum up experience through the treatment.Methods We cured the patients with obstructive sleep apnea-hypopnea syndrome who had been diagnosed by polysomnogram by Auto-CPAP,then observed the improvement in their subjective feelings and objective target aim such as blood pressure and SaO2.Results After treatment by Auto-CPAP.we found their symptom had been improved significantly,for example,the time of sleep apnea decreased or disappeared,the sleep structure had been improved evidently.Conclusion As intelligent CPAP,Auto-CPAP can provide the lowest effective therapy pressure from beginning to end though the inductorium in the face piece,and increase the ease and toleration of the patients,so the curative effects are remarkable.

Eosinophils ; immunology ; Food Hypersensitivity ; etiology ; Gastritis ; etiology ; Humans ; Infant ; Male ; Milk Hypersensitivity ; complications ; immunology ; Milk Proteins ; immunology

The brief discussion is introduced in the paper on the academic thought of professor YAN Jie, the contemporary famous TCM doctor, on functional dyspepsia treated with acupuncture and moxibustion. Treatment based on "the three-regional acupoint selection" is applied to professor YAN's treatment for functional dyspepsia, in which, acupuncture is on Sibai (ST 2), Liangmen (ST 21) and Zusanli (ST 36), and the supplementary points are added accordingly. The academic thought is described as the combination of acupuncture and moxibustion based on strengthening healthy qi, supplemented by soothing the liver and psychological counseling. Also, an example is provided.
Acupuncture ; education ; history ; Acupuncture Points ; Acupuncture Therapy ; history ; Adult ; Dyspepsia ; history ; therapy ; Female ; History, 20th Century ; Humans ; Moxibustion

Objective To evaluate the value of Kidney Disease:Improving Global Outcomes (KDIGO) criteria in investigating clinical feature and prognosis of acute kidney injury (AKI) patients with sepsis in ICU.Methods Clinical data of patients with AKI defined by KDIGO criteria in ICU of Wuxi People's Hospital from June 2007 to June 2012 were collected.Clinical characteristics,prognosis and major risk factors of death of septic AKI patients were retrospectively analyzed.Results Of the enrolled 703 AKI patients,395 (56.2％) were caused by sepsis (septic AKI),which indicated that sepsis mainly contributed to the causes of AKI.For septic AKI stratified by KDIGO classification,146(37.0％) patients belonged to AKI Ⅰ,154(39.0％) to AKI Ⅱ,and 95 (24.1％) to AKI Ⅲ.Compared with the patients with non-septic AKI,septic AKI patients had greater APACHE Ⅱ and SOFA score (25.1 ±4.9 vs 20.5 ±6.4,12.9 ±2.6vs 10.4 ± 4.5 ; all P values ＜ 0.05).Although there was no significant difference in baseline serum creatinine [(82.9 ± 22.2) μmol/L vs (83.1 ± 30.O) μmol/L,P ＞ 0.05] between the two groups,patients with sepsis had higher serum creatinine [(143.5 ± 21.6) μmol/L vs (96.2 ± 15.5) μmol/L; P ＜ 0.05],a higher proportion fulfilled KDIGO categories for both AKI Ⅱ and Ⅲ (63.0％ vs 33.1％ ; P ＜ 0.05),a higher renal replacement therapy (RRT) rate (22.3％ vs 6.2％ ; P ＜ 0.05) and a lower proportion of complete renal recovery(74.4％ vs 82.8％) (all P values ＜ 0.05).The 90-day mortality of septic AKI patients was higher than that of non-septic AKI patients (52.2％ vs 34.1％ ; P ＜ 0.05).Septic AKI,graded by KDIGO,was associated with an increased mortality.Logistic regression analysis showed that APACHE Ⅱ score (OR =5.451,95％ CI:3.095-9.416),SOFA score (OR =2.166,95％ CI:1.964-4.515) and RRT (OR =4.021,95％ CI:2.975-6.324) were independent risk factors for mortality of septic AKI patients.Conclusion Septic AKI patients have a higher burden of illness,worse renal function and higher mortality.APACHE Ⅱ score,SOFA score and RRT are independent risk factors to septic AKI mortality.

This article expounds the action mechanism on correlation between stomach meridians points and stomach as well as its perspective from myriad ancient and modern literature.

Objective:Matching pursuit algorithm(MAP),for its good parametric characterization, is applied in Magnetoencephalography(MEG) to study time-frequency distribution. Methods:This paper proposes to apply a high-resolution time-frequency analysis algorithm, the matching pursuit (MP), to extract detailed time-frequency components of SEF signals. Results: Experimental results on cortical SEF signals of several normal subjects show that a series of stable SEF time components can be identified using the MP decomposition algorithm. Conclusion:This study shows that there is a set of stable and minute time-frequency componentsin SEF signals, which are revealed by the MP decomposition. These stable SEF components have specific localizations in the time domain and may provide a reliable index for clinical research of brain function and brain disease pathogenesis.

Objective To determine whether triggering receptor expressed on myeloid cells-1 (sTREM-1) and urinary neutrophil gelatinase-associated lipocalin (NGAL) were early biomarkers of acute kidney injury (AKI) secondary to sepsis.Methods A total of 141 eligible patients were enrolled in this prospective study.Blood and urine samples were collected at different time points as soon as sepsis was diagnosed.The concentrations of serum creatinine (Scr),urine sTREM-1 and NGAL were measured.According to AKI criteria,patients were divided into the AKI group and non-AKI group.Dynamic changes of levels of Scr,urine sTREM-1 and NGAL were observed in two groups.The receiver operating characteristic curves were used to evaluate the early diagnostic value of urine sTREM-1 and NGAL.Results Among 141 septic patients,44 (31.2％) cases had concomitant AKI.Twenty four hours after sepsis diagnosed,the level of Scr rose to 1.91 times of the baseline [(140.5±13.6) vs (82.6± 15.3) μmol/L,P ＜ 0.05],which met the diagnostic criteria of AKI.In the AKI group,urinary concentrations of sTREM-1 and NGAL at 8 h after the diagnosis of sepsis began to rise significantly from baseline [(100.5±17.4) vs (38.9± 14.7) ng/L; (144.6±51.9) vs (56.2±43.8) μg/L,both P ＜ 0.05].And at the following time points,urinary concentrations of sTREM-1 and NGAL were significantly higher than the baseline levels and that of the non-AKI group (all P ＜ 0.05).At 8 h time point,thearea under the curve of urine sTREM-1 was 0.877 (95％CI 0.756-0.914),the sensitivity was 89.1％ and specificity was 82.0％ with a cutoff value of 70 ng/L.At 8 h time point,the area under the curve of urine NGAL was 0.862 (95％ CI 0.703-0.958),the sensitivity was 87.4％ and specificity was 85.5％ with a cutoff value of 90 μg/L.Conclusions Urinary concentrations of sTREM-1 and NGAL at 8 h time point after the diagnosis of sepsis have predictive value for AKI and their diagnostic time is much earlier than that of Scr.Therefore,urinary sTREM-1 and NGAL can be used as early biomarkers of septic AKI.

BACKGROUND:The appropriate choice of orthoses based on hemiplegic patient’s condition can improve motor function recovery in stroke patients.
OBJECTIVE:To review the motor function recovery of stroke patients with hemiplegia wearing different types of orthoses.
METHODS:Application of different types of orthoses in hemiplegic patients was reviewed through access to literature, as wel as effects of a variety of orthoses on the recovery of motor functions in hemiplegic patients.
RESULTS AND CONCLUSION:Orthoses can reduce limb muscle tension and muscle spasms, and improve motor function and overal daily living skil s in stroke patients with hemiplegia, which play a variety of roles, including stable support, fixed protection, correction of deformity and functional compensation. However, the long-term therapeutic effect of orthoses cannot be verified because of fewer cases, shorter time for therapeutic observation, and the lack of long-term fol ow-up. It is necessary to perform long-term fol ow-up for the verification of long-term efficacy of orthoses. Meanwhile, the appropriate timing for removal of orthoses needs further study.

BACKGROUND:Stem cells under appropriate conditions can be induced to differentiate into neuron-like cells. Chinese herbs can function in cellproliferation and differentiation.
OBJECTIVE:To investigate the interventional effects of traditional Chinese medicine on stem celltransplantation in the treatment of cerebrovascular diseases.
METHODS:Experimental studies concerning traditional Chinese medicine intervention for stem celltransplantation were retrieved and analyzed. Under specific conditions, stem cells can proliferate in vitro in a suspended or monolayer manner, and can be potential y induced to differentiate into neurons, oligodendrocytes and astrocytes, thereby providing basis for stem celltransplantation in the treatment of cerebrovascular diseases. We observed expressions of nestin, glial fibril ary acidic protein, and microtubule-associated protein expression for analysis of stem cellproliferation and differentiation.
RESULTS AND CONCLUSION:Baicalin or Astragalus saponin Ⅳ can stimulate stem cells to differentiate into nerve cells in vitro. Naomaitong or danshen combined with bone marrow mesenchymal stem celltransplantation can promote neurological recovery from cerebrovascular diseases in rats. Buyang Huanwu Decoction can significantly promote the proliferation of neural stem cells in the subventricular zone and neurological recovery after cerebral ischemia. Chinese herbs, such as Zhichan Decoction and Panax notoginseng, can promote survival of transplanted cells and prevent most cellapoptosis in the stem celltherapy for treatment of Parkinson’s disease. Therapy of benefiting qi and elevating yang or ginsenosides Rg1 combined with stem celltherapy can improve memory ability of dementia rats. Traditional Chinese medicine exerts a catalytic role in the stem celltherapy for cerebrovascular diseases.