Adolescent ; Humans ; Lung ; diagnostic imaging ; pathology ; Lung Neoplasms ; diagnostic imaging ; pathology ; surgery ; Male ; Papilloma ; diagnostic imaging ; pathology ; surgery ; Pneumonectomy ; methods ; Tomography, X-Ray Computed

The incidence of childhood inflammatory bowel disease has gradually increased in recent years.The disease is a chronic intestinal inflammatory disease, and its susceptible age is school age, which seriously affects the growth and development of children and brings psychological and spiritual trauma.The etiology and pathogenesis of inflammatory bowel disease is unclear, but with the in-depth study of the intestinal flora in recent years, it has been shown that intestinal flora imbalance plays an important role in the occurrence and development of the disease, and it has also been widely confirmed in clinical practice.Therefore, people try to use probiotics in the treatment of children with inflammatory bowel disease.This article mainly reviews the progress of the application of probiotics, prebiotics, fecal bacteria transplantation and other microecological agent in children with inflammatory bowel disease, analyzes the therapeutic effects of probiotics on children with inflammatory bowel disease, and provides new ideas for clinical practice.

Hemiplegia is a common type of physical disability in children with brain damage. For many kinds of reasons, the outcome of rehabilitation of the affected upper limb is not good enough, especially in the affected hand. Recently, many studies engaged in the modified Constraint-induced Movement Therapy (mCIMT) to explore the child-friendly way of restraint to improve hand function in hemiplegic children, and were summarized in this paper.

Disrupted pancreatic β-cell function and decreased β-cell number are two of the main causes of type 2 diabetes mellitus. Recent studies have indicated that autophagy plays an important role in protecting pancreatic β-cell and in maintaining the structure, number, and secretive function of pancreatic β-cell. Although autophagy has been a focus of study in recent years, including areas such as tumor, neural diseases and aging, but its relationship with pancreatic β-cell was not included. In this paper we review the concept of autophagy and its role in maintaining the normal function of pancreatic β-cells.

Objective To investigate the expression and clinical significance of Bmi-1,Podoplanin and p53 in human thymic epithelial tumor(TET) according to new histological classification of World Health Organization. Methods One hundred and ten TET tissue chips were prepared,and the expressions of Bmi-1,Podoplanin and p53 were detected by NovoLinkTM Polymer detection systems. Results The positive expressions of Bmi-1,Podoplanin and p53 were 68.2%,41.8% and 42.7%,respectively.The positive expressions of Bmi-1,Podoplanin and p53 were significantly associated with pathologic histological classification,Masaoka staging and clinic pathological grading(P

Abstract Human adenovirus (HAdV), which is characterized by infectivity, complex pathogenesis and multiple target organs, causes multiple organ infections in the respiratory system, gastrointestinal system and eyes, which seriously endangers human health. Various subspecies of HAdV has different tissue tropism, which presents diverse clinical symptoms and epidemiological characteristics. Based on the molecule biological characteristics of HAdV, this review summarizes the clinical symptoms and epidemiological characteristics of HAdV infections depending on tissue tropism, and describes the trends in HAdV epidemiology, so as to provide insights into prevention and control of HAdV infections.

Objective To analyse the differences between idiopathic and symptomatic childhood epilepsy with occipital patoxysms. Methods The medical records of 38 patients with interictal spikes and/or sharp waves over occipital areas,posterior temporal-parietal areas,or both were retrospectively analysed.Epidemiological data,ictal symptoms,electroencephalogram,neuroimaging studies,treatment response and prognosis were compared using chi-square test or Mann-Whitney U test. Results Four patients of idiopathic group had positive family history related to nervous system.Seizures were more frequent in symptomatic group than in idiopathic group.Both groups showed autonomic symptoms,while ictal vomiting and deviation of eyes were more common in the presence of Panayiotopoulos type.The prognosis of idiopathic group was much better than that of symptomatic group. Conclusion Panayiotopoulos syndrome is more common.Neurologic deficits and electroencephalographic characteristics are major factors to predict seizure remission in children with occipital lobe epilepsy.Idiopathic childhood epilepsy with occipital paroxysms may result in better prognosis.

AIDS has become a devastating disease facing human around the world.Western medicine can reduce blood HIV load,thereby promoting recovery of immune function. With the extensive application of HAART,many unsolvable problems appear.There is much experience in treatment for infectious diseases in TCM.So,it is necessary and feasible to treat AIDS with TCM.Combination of Chinese and western medicine will achieve complementary advantages and may be a new model for AIDS treatment.Many researchers carry out study on it,but there are still a lot to do to improve the drawbacks.

Disrupted pancreatic ?-cell function and decreased ?-cell number are two of the main causes of type 2 diabetes mellitus.Recent studies have indicated that autophagy plays an important role in protecting pancreatic ?-cell and in maintaining the structure,number,and secretive function of pancreatic ?-cell.Although autophagy has been a focus of study in recent years,including areas such as tumor,neural diseases and aging,but its relationship with pancreatic ?-cell was not included.In this paper we review the concept of autophagy and its role in maintaining the normal function of pancreatic ?-cells.

Objective To comprehend the etiology and the clinical characteristics of hypereosinophilia.Methods The clinical data of 53 patients with hypereosinophilia admitted to Peking Union Medical College Hospital from November 1992 to February 2005 were analyzed.Results The causes of reactive hypereosinophilia included allergic diseases,infections,connective tissue diseases,malignant diseases,lung diseases,eosinophilic gastroenteritis.idiopathic hypereosinophilic syndrome had longer course of disease;more organ involved than reactive causes.The incidence of lymph node enlargement,spleen enlargement and thrombus was higher than the reactive.IHES had higher level of white blood cell count,absolute eosinophilic count,IgG and CRP.Conclusion The etiology and clinical characteristics of hypereosinophilia are various,so the differential diagnosis of hypereosinophilia is very important.