1.Analysis on Therapeutic Features of Ancient Acupuncture Treatment for Impotence
Journal of Acupuncture and Tuina Science 2009;7(1):61-64
To analyze the acupuncture treatment for impotence in 130 kinds of classical medical books by computer,and summarize the rules of acupuncture for this disease.The results showed that selection of acupoints along the meridians,selection of acupoints by boay parts,selection ofacupoints by pattern identification are the laws ofacupuncture for this disease.
2.Relationship between serum ferritin levels and cardiovascular risk in different genders of Chinese
Chinese Journal of General Practitioners 2017;16(1):39-44
Objective To evaluate the association between serum ferritin and the risk of cardiovascular disease among the Chinese population.Methods Based on the data from China Health and Nutrition Survey 2009, we used the Framingham risk score to calculate the 10-year risk of cardiovascular disease and analyzed the association between serum ferritin and the risk of cardiovascular disease in different gender by logistic regression analysis.Results Among 6 551 respondents, 3 035 (46.3%) were males and 3 516 ( 53.7%) were females whose mean age were ( 49.3 ±13.8 ) and ( 49.2 ±13.7 ) years, respectively.The median level of serum ferritin was 75.08 ( 36.71 -138.75 )μg/L.According to the 10-year risk of cardiovascular disease calculated by the Framingham risk score , the low risk group, middle risk group and high risk group were accounted for 79.5%( n=5 207 ) , 15.7% ( n=1 028 ) and 4.8%( n=316), respectively.The median of serum ferritin (121.61 vs.46.14, P<0.01) and the Framingham risk score (8.6 ±6.0 vs.7.3 ±1.6, P<0.01) of males were higher than those of females.The percentages of the middle risk group ( 30.6% vs.2.8%) and high risk group ( 9.8% vs.0.5%) of 10-year risk of cardiovascular disease in males were higher than those in females ( P <0.01 ).The 10-year risk of cardiovascular disease ≥10%increased with the increasing of serum ferritin in females ( trend P<0.01 ) but not in males.Conclusion Serum ferritin levels are positively correlated with the risk of cardiovascular disease in female Chinese.
4.Study on composition of essential oil in above-ground and root of Bupleurum malconense and root of B. chinense by AMDIS and retention index.
Jie YAN ; Ying-Fang WEI ; Rui GU
China Journal of Chinese Materia Medica 2014;39(6):1048-1053
Chemical constituents of the essential oil in above-ground and root of Bupleurum malconense and root of B. chinense were investigated by GC-MS compiled with automated mass spectral deconvolution and identification system (AMDIS) and retention index. The results showd that the components of essential oil in B. malconense have some similarities with the one in B. chinense, and both of them have the higher content of caryophyllene oxide which is an active component of anti-inflammatory and analgesic. These results suggested that as a local substitute, B. malconense has a certain scientific basis of the treatment for cold fever.
Bupleurum
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chemistry
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Drugs, Chinese Herbal
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chemistry
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pharmacology
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therapeutic use
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Fever
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drug therapy
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Mass Spectrometry
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Oils, Volatile
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chemistry
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Plant Roots
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chemistry
5.Observation of the immune effect and the security after inoculating rabies vaccine in children
Qiqiang LONG ; Jie QIU ; Xiaojun GU
Chinese Journal of Primary Medicine and Pharmacy 2008;15(10):1605-1606
Objective To investigate the immune effect and the security after inoculating rabies vaccine in children. Methods To investigate and to detect the antibody level by the way of ELISA among the 337 children wounded by animals and vaccined the rabies vaccine. Results The positive rate of the antibody is 99.7%, the ad-verse effect is moderate. Conclusion Domestic adjuvant-free aqueous rabies vaccine, domestic freeze dried rabies vaccine and peregrinus freeze dried rabies vaccine all have satisfactory immunogenicity and little adverse effect.
6.Pharmacodynamic Effect of Antiviral Shenghuangketong Ointment on Mice
Jie YANG ; Xiqiu ZHAO ; Sujun GU
Chinese Journal of Nosocomiology 1994;0(04):-
OBJECTIVE To study the antiviral effect of Shenghuangketong ointment(SO)in vivo experiments.METHODS The inhibition effect of SO on the HSV-infected mice with the estimation of its antiviral action.RESULTS SO had an obvious antiviral action and the inhibition effect on the HSV-infected mice.There was significant difference P
7.Further discussion on objective structured teaching evaluation: two key questions
Jie GU ; Zhigang PAN ; Shanzhu ZHU
Chinese Journal of General Practitioners 2017;16(2):163-166
The objective structured teaching evaluation (OSTE) is a new method for training and objective assessment of the teaching ability of clinical faculty by using standardized students and teaching scenario.It is mainly used to evaluate training programs,train teaching skills and assess teaching ability of clinical faculty.The differences and association between teaching ability,teaching skills and teaching scenario should be clarified before designing OSTE.Although there are some differences in various studies,OSTE can be summarized into two aspects:teaching administration knowledge and special teaching skills.Given the great potential of OSTE in training and assessing faculty,medical educators in general should actively explore its concept and application.
8.Diagnostic analysis of different index in adult onset Still's disease
Zhen WANG ; Lindi JIANG ; Jie GU
Chinese Journal of Rheumatology 2010;14(3):192-194
Objective To evaluate the value of clinical findings and different diagnostic criteria for the diagnosis of adult onset Still's disease (AOSD). Methods The AOSD patients admitted to Zhongshan Hospital affiliated to Fudan University from 2003 to 2009 were enrolled. Non-AOSD patients with fever were selected. Different diagnostic criteria of AOSD were applied to all patients. Two indenpendent samples t test and wilco-xon test were used for statistical analysis. Results The clinical features such as rash, arthralgia, arthroncus, sore throat, myalgia, lymph node enlargement, hepatomegaly, splenomegaly, leuko-cytosis, neutrophil ≥80% and serum level of ferrin≥ 2000 ng/ml hadhigher specificity (65.87%~98.41%) with 2.00~5.00 of the positive likelihood ratio.High fever ( ≥39.0℃), negative of ANA and RF had higher sensi-tivity (85.25%~93.65%). Combinations of three parameters such as high fever, rash, sore throat, leukocy-tosis, arthralgia had higher positive likelihood ratio. The specificity of ARA criteria was the highest. The sensitivity and accuracy of Yamaguchi criteria were the highest. Conclusion There is no single parameter that could be specific to the identification of AOSD. Combing with several parameters can improve the diagnostic efficiency. The results of this study have shown that the commonly used diagnostic criteria has high specificity.
9.Characteristics of Acupuncture Treatment of Dementia in Ancient Times
Ligong LIU ; Jie GU ; Yuanchun XIAO
Journal of Acupuncture and Tuina Science 2003;1(1):12-14
This paper makes a statistical analysis on the acupuncture treatment of dementia recorded in 93 ancient books. The statistics show that the common acupoints are Shenmen ( HT 7), Shaoshang ( LU 11 ),Dazhong ( KI4), Yinbai ( SP 1 ), Houxi ( SI 3 ), Xinshu (BL 15), Yongquan (KI 1), Jiuwei (CV 15) and Baihui (GV 20); the common meridians are the Heart Meridian, Bladder Meridian and Kidney Meridian; the common areas are palm, medial side of leg, upper back and head; the acupoints of the heart meridian are frequently used, especially those in the distal end;heavy moxibustion functions to open orifices and needling to regulate qi.
10.High-resolution melting analysis for detection of K-ras mutation in colorectal cancer and its clinical significance
Journal of Medical Postgraduates 2015;(8):840-842
Objective The K-ras gene plays a major role in the development , progression, and drug selection for the target treatment of colorectal cancer .The aim of this study was to evaluate the feasibility of detecting K-ras mutation in colorectal cancer by high-resolution melting ( HRM) analysis and to investigate the relationship between K-ras mutation and the clinicopathological parame-ters of colorectal cancer. Methods We collected the tissue samples of colorectal cancer from 179 patients, detected the mutations in codons 12 and 13 of the K-ras gene, and analyzed the relationship between K-ras mutation and the clinicopathological parameters of the patients. Results In the 179 cases of colorectal cancer, K-ras mutation was found in 77 (43.02%), significantly higher in those aged ≥60 years than in those aged <60 years (55.17% vs 33.70%, P<0.05).Multivariate logistic regression analysis showed a significant influence of age on K-ras mutation (OR=1.506, 95%CI:1.028-2.011, P<0.05). Conclusion HRM analysis is a rapid, sensitive, and inexpensive diagnostic tool for the detection of K-ras mutation, and K-ras mutation is associated with the age of colorectal cancer patients .