1.Four Aspects of Strengthening Management on Medical Equipment
Liang SHI ; Yuhai TIAN ; Jian LUO
Chinese Medical Equipment Journal 1989;0(04):-
The management of medical equipment is one of the important parts in hospital management,which management quality can directly affect the hospital central task and disciplines construction.How to strengthen the management of medical equipment are studied from the plan of medical equipment,the purchase,book building and application four aspects.
2.Monitoring data wire transmission technology for oxygen supply in hospital
Qingfan PANG ; Jian LUO ; Liang CUI ; Erping LUO
Chinese Medical Equipment Journal 1989;0(03):-
Data exchanged through public telephone networks and the singlechip systems in devices of terminals and center, a kind of monitoring data wire transmission technology for oxygen supply in hospital is introduced in this paper. With high quality of signal transmission and infrequent distortions of signals, the technology can be applied to realtime supervising of oxygen supply system.
3.Analysis of balanced translocation at amniocentesis on prenatal diagnosis
Xiaojin LUO ; Liang HU ; Jian RAN ; Fengxiang WEI
The Journal of Practical Medicine 2015;31(23):3904-3906
Objective To explore the prenatal indications and pregnant outcome of balanced transloca-tion at amniocentesis, so as to provide scientific guidelines of prenatal diagnosis for local pregnant women. Methods Retrospective review was made on 76 cases of balanced translocation at amniocentesis from 2011 to 2015 at our hospital. Results In 76 cases, 38 cases were aged pregnancy prenatally, 20 cases carriers, 9 cas-es abnormal serum screening , 5 cases with previous abnormal births , 2 cases with abnormal ultrasound findings and 2 cases with other problems. Conclusion Balanced translocation concomitant aneuploidy , de novo X-auto-some translocation or de novo complex chromosome rearrangements can cause fetal abnormalities on prenatal di-agnosis. The results of ultrasound, FISH and array-CGH could provide for de novo simple translocation at amnio-centesis.
4.Roles of atypical chemokine receptors in progression and metastasis of tumor
Jian LUO ; Dongning LI ; Lu KONG ; Cong LI ; Pin LIANG
Chinese Journal of Pathophysiology 2015;33(4):764-768
[ ABSTRACT] Chemokines and their receptors have been implicated mostly in tumor progression and metastasis. Atypical chemokine receptors ( ACKRs) comprise a group of 7-transmembrane domain proteins structurally similar to G pro-tein-coupled receptors.However, ACKRs do not induce classical signaling via the typical G protein-mediated pathways. ACKRs efficiently internalize the cognate chemokine ligands and act as scavengers instead.ACJRs are composed of at least 3 members of chemokine receptors: Duffy antigen receptor for chemokines ( DARC, also known as ACKR1 ) , D6 ( also known as ACKR2) and ChemoCentryx chemokine receptor (CCX-CKR, also known as ACKR4).These receptors bind to and/or internalize their chemoattractant ligands without activating signal transduction cascades leading to cell migration.In this review, we summarize the recent progress regarding the roles of ACKRs in the progression and metastasis of tumor.
5.Application and development of ultrasonic technology in medical field
Na WEI ; Jiqing YANG ; Jian LUO ; Liang CUI
Chinese Medical Equipment Journal 2004;0(08):-
Based on the physical characteristic of ultrasound, the images of body tissues can be obtained through ultrasonic medical technology, which is another flourishing cross-linked branch of BME after X ray technology. Being non-invasive, painless and reusable, ultrasonic medical technology is suitable for the examination and treatment of the soft tissue. This paper introduces such of ultrasonic technology as its basic principle, developing prospect and application to clinical medicine.
6.The development of ultrasound Doppler error detection equipment
Na WEI ; Jiqing YANG ; Jian LUO ; Liang CUI
Chinese Medical Equipment Journal 1989;0(01):-
In the field of medical engineering, ultrasonic Doppler technology develops rapidly and gains wide application. MICS-51 is one of the main series of MCU family and has been widely used in China. In this paper, the ultrasound Doppler error detection equipment based on MCS-51 is introduced.
7.Inhibitory Effect of Kaixin Capsule on Gene Expression of Myocardial Immune Inflammatory Factor in Dogs After Resuscitation
Xiaoxing LUO ; Dawei WANG ; Yonghua ZHAO ; Jian LIANG
Journal of Guangzhou University of Traditional Chinese Medicine 2004;0(05):-
【Objective】 To investigate the effect of Kaixin Capsule (KC) on gene expression of myocardial immune inflammatory factor in dogs after resuscitation and to search for an effective way to counteract the progress of systemic inflammatory response syndrome (SIRS) after cardiopulmonary resuscitation. 【Methods】 Fifteen hybrid dogs were randomly divided into three groups, 5 dogs each: pseudo-operation group (group A), model group (group B) and KC group (group C). The dog model of cardiac arrest and resuscitation was established; the dogs were executed and the heart was isolated 180 min after the recovery of autonomic circulation. Myocardial total RNA was extracted and the mRNA expression of objective gene was detected by reverse transcription polymerase chain reaction (RT-PCR). 【Results】 mRNA expression of Toll-like receptor (TLR_4) and tumor necrosis factor ?(TNF-?) in group B differed from that ingroup A (P
8.Enforcement of Medical Equipment Management
Liang SHI ; Xia CAO ; Zhanlin XIE ; Jian LUO
Chinese Medical Equipment Journal 2004;0(09):-
The management methods of medical equipment are discussed in the following 7 aspects: archives management,use management,maintenance,metrology management,new knowledge learning,enhancement of staff's skill and personnel cultivation.
9.Expression of Survivin and Bcl-2 in sinonasal inverted papilloma
Jinhui LIANG ; Shan GAO ; Jian ZHANG ; Hongmin AO ; Xianlin WEI ; Hailin LUO
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2009;(20):933-935
Objective:To investigate the expression of Survivin and it's relationship with the expression of Bcl-2 in sinonasal inverted papilloma (SNIP).Method:Immunohistochemical method was used to determine the expression of Survivin and Bcl-2 in 30 cases of SNIP,10 cases of sinonasal squamous cell carcinoma(SCC) and 10 cases of normal inferior concha tissues.Result:Survivin was expressed in 22 of 30(73.3%)cases of SNIP,8 of 10(80.0%)cases of SCC and not expressed in 10(0%)cases of normal inferior concha tissues.Expression of Survivin was significantly higher in SNIP and SCC than in normal tissues.Bcl-2 was expressed in 9 of 10(90.0%)cases of SCC and 2 of 10(20.0%)cases of normal inferior concha tissues.Expression of Bcl-2 was significantly higher in SCC than in normal tissues.Bcl-2 was expressed in 14 of 30(46.7%)cases of SNIP,higher than normal tissues.Expression of Bcl-2 was positively related to expression of Survivin.Conclusion:Survivin may play an important role in the pathway of progression of SNIP and SCC.It may be identified as a new therapeutic target.Bcl-2 may play a synergic role with Survivin in progression of SNIP.
10.Hepatocyte growth factor attenuates hypoxia/reoxygenation injury in cortical neurons
Zhixing HU ; Jumin GENG ; Daoming LIANG ; Lanou WU ; Chunlan ZHENG ; Haiyun LUO ; Jian TAO
Basic & Clinical Medicine 2010;30(4):369-373
Objective To investigate the protective effect of hepatocyte growth factor (HGF) on cultured Sprague-Dawley rat cortical neurons injured through hypoxia/reoxygenation.Methods Primary cultured cerebral cortical neurons were isolated from newborn rots.Neurons were pre-incubated with different concentrations (15,30 and 60 μg/L) of HGF.The cell viability was detected by MTT.Apoptosis was measured by Hoechst 33258 staining and flow cytometer.Lactate dehydrogenase (LDH) and caspase-3 activity were determined by colorimetry.Results Compared with normal group,hypoxia/reoxygenation treatment significantly decreased cell viability,increased LDH activity and the percentage of apoptotic cells.Pretreatment of HGF for 12 h could remarkably reverse the decrease of cell viability and the increase of apoptosis rate in neurons induced by hypoxia/reoxygenation treatment.HGF pre-treatment also attenuated the activity of LDH and caspase-3 in a dose-dependent manner.The effects of HGF could be inhibited by a special PI3K/Akt pathway inhibitor,LY294002.Condusion HGF could attenuate rat cortical neuron injury induced by hypoxia/reoxygenation.The neuroprotective effect of HGF may be related to activating PI3K/Akt pathway,and further suppressing the expression of caspase-3.