1.Four Aspects of Strengthening Management on Medical Equipment
Liang SHI ; Yuhai TIAN ; Jian LUO
Chinese Medical Equipment Journal 1989;0(04):-
The management of medical equipment is one of the important parts in hospital management,which management quality can directly affect the hospital central task and disciplines construction.How to strengthen the management of medical equipment are studied from the plan of medical equipment,the purchase,book building and application four aspects.
2.Monitoring data wire transmission technology for oxygen supply in hospital
Qingfan PANG ; Jian LUO ; Liang CUI ; Erping LUO
Chinese Medical Equipment Journal 1989;0(03):-
Data exchanged through public telephone networks and the singlechip systems in devices of terminals and center, a kind of monitoring data wire transmission technology for oxygen supply in hospital is introduced in this paper. With high quality of signal transmission and infrequent distortions of signals, the technology can be applied to realtime supervising of oxygen supply system.
3.Enforcement of Medical Equipment Management
Liang SHI ; Xia CAO ; Zhanlin XIE ; Jian LUO
Chinese Medical Equipment Journal 2004;0(09):-
The management methods of medical equipment are discussed in the following 7 aspects: archives management,use management,maintenance,metrology management,new knowledge learning,enhancement of staff's skill and personnel cultivation.
4.Inhibitory Effect of Kaixin Capsule on Gene Expression of Myocardial Immune Inflammatory Factor in Dogs After Resuscitation
Xiaoxing LUO ; Dawei WANG ; Yonghua ZHAO ; Jian LIANG
Journal of Guangzhou University of Traditional Chinese Medicine 2004;0(05):-
【Objective】 To investigate the effect of Kaixin Capsule (KC) on gene expression of myocardial immune inflammatory factor in dogs after resuscitation and to search for an effective way to counteract the progress of systemic inflammatory response syndrome (SIRS) after cardiopulmonary resuscitation. 【Methods】 Fifteen hybrid dogs were randomly divided into three groups, 5 dogs each: pseudo-operation group (group A), model group (group B) and KC group (group C). The dog model of cardiac arrest and resuscitation was established; the dogs were executed and the heart was isolated 180 min after the recovery of autonomic circulation. Myocardial total RNA was extracted and the mRNA expression of objective gene was detected by reverse transcription polymerase chain reaction (RT-PCR). 【Results】 mRNA expression of Toll-like receptor (TLR_4) and tumor necrosis factor ?(TNF-?) in group B differed from that ingroup A (P
5.Application and development of ultrasonic technology in medical field
Na WEI ; Jiqing YANG ; Jian LUO ; Liang CUI
Chinese Medical Equipment Journal 2004;0(08):-
Based on the physical characteristic of ultrasound, the images of body tissues can be obtained through ultrasonic medical technology, which is another flourishing cross-linked branch of BME after X ray technology. Being non-invasive, painless and reusable, ultrasonic medical technology is suitable for the examination and treatment of the soft tissue. This paper introduces such of ultrasonic technology as its basic principle, developing prospect and application to clinical medicine.
6.The development of ultrasound Doppler error detection equipment
Na WEI ; Jiqing YANG ; Jian LUO ; Liang CUI
Chinese Medical Equipment Journal 1989;0(01):-
In the field of medical engineering, ultrasonic Doppler technology develops rapidly and gains wide application. MICS-51 is one of the main series of MCU family and has been widely used in China. In this paper, the ultrasound Doppler error detection equipment based on MCS-51 is introduced.
7.Roles of atypical chemokine receptors in progression and metastasis of tumor
Jian LUO ; Dongning LI ; Lu KONG ; Cong LI ; Pin LIANG
Chinese Journal of Pathophysiology 2015;33(4):764-768
[ ABSTRACT] Chemokines and their receptors have been implicated mostly in tumor progression and metastasis. Atypical chemokine receptors ( ACKRs) comprise a group of 7-transmembrane domain proteins structurally similar to G pro-tein-coupled receptors.However, ACKRs do not induce classical signaling via the typical G protein-mediated pathways. ACKRs efficiently internalize the cognate chemokine ligands and act as scavengers instead.ACJRs are composed of at least 3 members of chemokine receptors: Duffy antigen receptor for chemokines ( DARC, also known as ACKR1 ) , D6 ( also known as ACKR2) and ChemoCentryx chemokine receptor (CCX-CKR, also known as ACKR4).These receptors bind to and/or internalize their chemoattractant ligands without activating signal transduction cascades leading to cell migration.In this review, we summarize the recent progress regarding the roles of ACKRs in the progression and metastasis of tumor.
8.Analysis of balanced translocation at amniocentesis on prenatal diagnosis
Xiaojin LUO ; Liang HU ; Jian RAN ; Fengxiang WEI
The Journal of Practical Medicine 2015;31(23):3904-3906
Objective To explore the prenatal indications and pregnant outcome of balanced transloca-tion at amniocentesis, so as to provide scientific guidelines of prenatal diagnosis for local pregnant women. Methods Retrospective review was made on 76 cases of balanced translocation at amniocentesis from 2011 to 2015 at our hospital. Results In 76 cases, 38 cases were aged pregnancy prenatally, 20 cases carriers, 9 cas-es abnormal serum screening , 5 cases with previous abnormal births , 2 cases with abnormal ultrasound findings and 2 cases with other problems. Conclusion Balanced translocation concomitant aneuploidy , de novo X-auto-some translocation or de novo complex chromosome rearrangements can cause fetal abnormalities on prenatal di-agnosis. The results of ultrasound, FISH and array-CGH could provide for de novo simple translocation at amnio-centesis.
9.Single nucleotide polymorphisms of folate metabolism pathway genes in central chinese families with neural tube defects
Jian LIU ; Jing QI ; Jie ZHU ; Lixia ZHANG ; Qin NING ; Yan LIANG ; Xiaoping LUO
Chinese Journal of Perinatal Medicine 2010;13(5):384-389
Objective To investigate the contribution of single nucleotide polymorphisms (SNP)variation in folate metabolism pathway genes and its interaction with environmental risk factors to the etiology of NTD. Methods In 275 families from central China, a total of 278 aborted fetal tissues or blood samples were collected from NTD individuals, 478 maternal and/or paternal blood samples were also obtained as controls. Folate supplementation, maternal diabetes mellitus and medication before pregnancy and during the first trimester of pregnancy were investigated. SNP analyses of all samples were performed by CEQ 8800. Case-parent control study and transmission/disequilibrium tests (TDT) were performed according to environmental cofactors stratification to evaluated 28 SNP in 12 folate pathway genes associated with human NTD. Results Only gene MTHFR rs1801133 was significantly associated with NTD, and synergistic effects of environmental risk factors (no folate supplementation and maternal diabetes) were shown on the occurrence of NTD. Linkage disequilibrium between BHMT rs3733890 and NTD existed in case of no folate supplementation,whereas the genotype alone did not contribute to the etiology of NTD. Other SNP were not significantly associated with NTD. Conclusions MTHFR rs1801133 is a risk factor of NTD, but BHMT rs3733890 is not an independent risk factor. Further investigations in folate and methionine cycle genes are requird in larger scale to enclose the interactions between gene and gene, or gene and environmental factors.
10.Expression changes of aquaporin during ischemic reperfusion injury to rat kidney
Rixin ZHANG ; Liming WANG ; Shuliang CHEN ; Zhenming GAO ; Shu WANG ; Jian MIAO ; Fuwen LUO ; Rui LIANG
Chinese Journal of Tissue Engineering Research 2009;13(53):10499-10503
BACKGROUND: It is a hot investigation to many scholars that how to cure and prevent renal ischemic reperfusion injury in a utility way, but the mechanism is unclear at present. The investigation indicates that aquaporiin-1 plays an important role during this process. OBJECTIVE: To research the correlation between aquaporin-1 expression and renal function change following renal ischemic reperfusion injury. DESIGN, TIME AND SETTING: A randomized controlled animal experiment was performed at Histology and Embryology Laboratory of Dalian Medical University from June 2007 to December 2008. MATERIALS: A total of 80 healthy female adult Wister rats were randomly divided into control group and ischemia-reperfusion group. Rats in each group were observed at days 1, 2, 3, 5, and 7 after operation, with 8 rats for each group. The ischemia-reperfusion injury was established on the left kidney. METHODS: Right kidney was removed. The left renal pedicle was freed and occlused to establish ischemia-reperfusion injury model. After 40 minutes, the blood was re-flowed. If the kidney colored from dark red to bright red within 2-5 minutes, the ischemia-reperfusion injury models were successfully established, and the thrombus was not formed in the kidney vessels. If the kidney was still dark red after 5 minutes, the thrombus was formed, and the rats were excluded from the ischemia-reperfusion group. The abdomen was sutured after 40 minutes.MAIN OUTCOME MEASURES: Rats were sacrificed at days 1, 2, 3, 5, and 7 after ischemia-reperfusion injury. Samples of urine, serum, and kidney were performed with the examinations of urine, renal function, renal pathology and morphology, immunohistological assay of aquaporiin-1, and RT-PCR assay. RESULTS: After ischemia-reperfusion injury, the rats had hydrouria, urine osmotic pressure depress, symptoms of carnine and urea nitrogen increasing. HE staining demonstrated that renal tubular epithelial cells were swelling, necrosis, and desquamate. Aquaporin-1 expression and its mRNA level was decreased; in particular, the expression and level were the lowest at day 1 after ischemia-reperfusion injury and recovered to normal value at day 5 after ischemia-reperfusion injury. CONCLUNSION: The down expression of aquaporin-1 maybe one of the important indicators to reflect renal functional changes of acute renal failure following renal ischemia-reperfusion injury.