1.Development and problem of soft tissues neoplasms.
Chinese Journal of Pathology 2005;34(3):129-132
2.Fibrohistiocytic tumor of skin.
Chinese Journal of Pathology 2013;42(2):134-137
Actins
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metabolism
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Dermatofibrosarcoma
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classification
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pathology
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Desmin
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metabolism
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Head and Neck Neoplasms
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metabolism
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pathology
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Histiocytoma, Benign Fibrous
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classification
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metabolism
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pathology
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Histiocytoma, Malignant Fibrous
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classification
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metabolism
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pathology
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Humans
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Oncogene Proteins, Fusion
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metabolism
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Skin Neoplasms
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metabolism
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pathology
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Vimentin
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metabolism
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Xanthomatosis
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pathology
3.Clinical observation of adefovir dipivoxil in the treatment of hepatitis B ptients with HBeAg positive
Chinese Journal of Primary Medicine and Pharmacy 2013;20(7):986-988
Objective To evaluate the safety and effect of adefovir dipivoxil (ADV) on hepatitis B in HBeAgpositive patients.Methods 131 patients were divided into two groups randomly.Two groups were treated with ADV (10mg/d)and matrine (0.6g/d),respectively.The rate of HBV negative,the normalization rates of ALT,HBeAg loss and anfi-HBe seroconversion were evaluated respectively.Results After 12 weeks of treatment,the rate of HBV negative,the normalization rates of ALT,HBeAg loss and anti-HBe seroconversion of ADV were all significantly higher than those of matrine group(53.2% vs 7.8%,36.0% vs 8.7%,13.6% vs 3.1%,6.2% vs 0,respectively,x2 =56.32,23.18,all P < 0.01).Conclusion The domestic ADV superior to matrine in HBeAg-positive patients.
4.Discussion on Application of Four Qu-Shi Methods in Treatment of Ulcerative Colitis
World Science and Technology-Modernization of Traditional Chinese Medicine 2014;(5):1153-1155
The pathogenesis of ulcerative colitis (UC) is spleen-stomach weakness with dampness. Therefore, Qu-Shi (QS, eliminating dampness) is the main treatment principle. According to different pathogens, four QS methods in the UC treatment were summarized based on clinical experiences. In the clinic , the application of heat-clearing and dampness-eliminating, warm yang and dampness-eliminating, dampness-eliminating with bitter and pungent, spleen-reinforcing and dampness-eliminating. The indications should be identified for the application of principle-method-prescription-medicine. The flexible application of four methods mentioned above can increase the clinical efficacy.
5.Attach importance to the speciality in the diagnosis and treatment of diseases in biliary-pancreatic-duodenal junction
Chinese Journal of Digestive Surgery 2012;11(5):419-421
Biliary-pancreatic-duodenal junction is a special region in the human body.It is difficult to diagnose and treat diseases in this region because of the complicated anatomy,the limitation of diagnosing methods,the variety of disease,the high risks of operation and the severity of complications. We should pay more attention to the pathophysiology aspects and the laboratory researches of diseases in this region.Proper diagnosis and combination of different diagnosing methods could improve the rate of early diagnosis and identify the characteristics of the disease. Individualized operation should be considered to deal with iatrogenic injury of biliary-pancreatic-duodenal junction according to different patients' condition.The principle of operation is to control damage firstly and to preserve the function of biliary-pancreatic-duodenal junction and the physiological passway of bile and pancreatic juice to the greatest extent.
6.The efficay of paclitaxel combined with gemcitabine for patients with anthracycine-resistant metastatic breast Cancer
Chinese Journal of Primary Medicine and Pharmacy 2011;18(18):2455-2456
ObjectiveTo evaluate the clinical efficacy and toxicity of the regimen of paclitaxel combined with gemcitabine for anthracycine-resistant metastatic breast cancer. MethodsThirty patients with anthracycine-resistant metastatic breast cancer were enrolled in the study: paclitaxel 135mg/m2 infusion on day 1; Gemcitabine 850mg/m2 infusion on day 1,8 ,and administered in three weeks cycle. The clinical efficacy was evaluated every two cycles. ResultsOf all thirty patients qualified for efficacy analysis and among them CR 3 cases( 10% ) ,PR 11 cases (36.7 % ), SD 11 cases ( 36.7% ), and PD 5 cases ( 16.7% ), with an overall response rate of 46.7%. The median TTP and overall survival in those 30 patients was 7.1 and 15.6 months. The main toxicities with grade 3 and 4 were hypoleucocytosis in 10 patients(30.0% ) ,thrombocytopenia in 4 patients( 13.3% ). ConclusionThe regimen of paclitaxel combined with gemcitabine was effective,well-tolerated scheme in the anthracycine-resistant metastatic breast cancer.
7.Management of delayed-diagnosed iatrogenic injury in cho-ledocho-pancreatico-duodenal junction
Chinese Journal of Digestive Surgery 2009;8(3):179-180
Iatrogenic injury in choledocho-pancreatico-duodenal junction is usually difficult to discover in the course of operation because of its unique anatomical position. The injury can lead to postoperative chilis, fever, pain and swelling of the waist, which would easily be misdiagnosed as acute necrotizing pancreatitis. Controlling operations, such as bile and pancreatic juice separation, duodenal diverticularization, jejunal fistulation for enteral nutrition and abdominal drainage should be performed in dealing with the injury in choledocho-pancreatico-duodenal junction. Combined application of pyloric suture with absorbable thread and ligatian, gastric fistulation, ligation of the distal common bile duct and T-tube drainage is minimally invasive, and can fulfill a fully separation of bile and pancreatic juice and duodenal diverticularization. It will improve the possibility of secondary radical operation by ameliorating pyemia and general nutritional condition.
8.The clinical study of febrile convulsion.
Chinese Journal of Practical Internal Medicine 2006;0(S1):-
Objective To study the differences of electrolytes,C-reactive protein in different type,gender and recur- rent of febrile convulsion.Methods 174 cases of children febrile convulsion were collected.We detected the electro- lytes,C-reactive protein respectively and analyzed their relationship.Results In children febrile convulsion,the lev- els of the electrolytes,C-reactive protein had nothing to do with the type,gender and recurrent of the febrile convul- sion.Conclusion We should treat routinely the children who suffered from febrile convulsion without considering the type,gender and recurrent.
9.Relationship between HCV chronic infection and expression of IL-8,IP-10,Mig
Journal of Third Military Medical University 2003;0(13):-
Objective To study the relationship between HCV chronic infection and expression of CXC chemokines mRNA.Methods The levels of IL-8,IP-10 and Mig mRNA in peripheral blood mononuclear cells(PBMC) of chronic hepatitis C patients were detected by real-time quantitative polymerase chain reaction(RT-PCR) before,and 3,6 months after combined therapy of interferon-?(IFN-?) and Ribavirin.The rate of chemokine/GAPDH was regarded as the extreme level of chemokine.Results The mean level of HCV-RNA and expressive levels of IL-8,IP-10,Mig mRNA in peripheral blood of HCV chronic infection were 2.09?10~(6)copies/ml,and(1.243 7?0.071 2),(0.682 8?0.073 8),(0.668 3?0.075 4),with significant difference with those of normal controls(P0.05).Conclusion The expressions of IL-8,IP-10 and Mig mRNA in PBMC are high in patients with chronic hepatitis C,and associated with the replication level of HCV,and less associated with the gene type of HCV.IFN-? can effectively restrain the replication of HCV and down-regulate the levels of IL-8,IP-10 and Mig mRNA near to normal level in patients with chronic hepatitis C.IFN-? plays an important role in down-regulating inflammation response and controlling the development of the patients' condition.
10.Nutritional therapy of gestational diabetes mellitus and impaired glucose tolerance
Parenteral & Enteral Nutrition 2004;0(05):-
Objective:To study the nutritional therapy of GDM and IGT.Methods:50 g glucose challenge test was done 610 in patients at examination in our hospital.The oral glucose tolerance test(OGTT)was performed in glucose challenge test positive patients to diagnose GDM and IGT.The blood glucose of fasting and postprandial 2h,perinatal mortality,incidence of large neonates were observed after treatment with nutrition in the GDM and IGT patients.Results:There were 15 cases of GDM and 61cases of IGT during the 140 cases of GCT positive patients.After nutritional therapy,the GDM's fasting and postprandial 2 h blood glucose decreased significantly(P