Efficacy of praziquantel (Cesocide injection) by intramuscular (I.M.) route against cestode infections was evaluated. Total 93 domestic or laboratory animals such as dogs, cats, rats, mice, goats, deers and chickens were used. Animals were infected with Dipylidium caninum, Spirometra sp., Taenia pisiformis, Taenia taeniaeformis, Hymenolepis nana, Moniezia expansa, Moniezia sp. or Raillietina sp. A single dose of praziquantel, 6 mg/kg of body weight, was highly effective (97.9%) against cestodes of various kinds disregarding the host species or their intensity of infection. At high dose above 6 mg/kg, the cure rate was 100%. All the cestodes treated were expelled from the host within 48 hours. The discharged proglottids were damaged severely except Hymenolepis nana and Moniezia expansa. Intramuscular injection of this drug evoked a brief pain response in a dog, but no other side reactions were observed.
parasitology-helminth-cestoda ; Dipylidium caninum ; Spirometra sp. ; Taenia pisiformis ; Taenia taeniaeformis ; Hymenolepis nana ; Moniezia expansa ; Moniezia sp. ; Raillietina sp. ; dog ; cat ; rat ; mouse ; goat ; deer ; chicken ; chemotherapy ; praziquantel ; intramuscular injection ; animals ; tapeworms ; cestodes

No abstract available.
Injections, Intramuscular* ; Pilomatrixoma* ; Vaccination

The fibrosis involved in gluteus maximus causing limitation of flexion and adduction of the hip has become a recognized clinical entity since the first report by Fernandez de Valderrma in 1969. Its most constant and characteristic histologic feature was substitution of the fibrous tissue in the definitive etiology was unknown but presumed to be multiple intramuscular injections. Authors present three cases of the fibrosis involving gluteus maximus. In two cases Z-lengthening was performed on the thickened fibrous bands with good results.
Fibrosis ; Hip ; Injections, Intramuscular

Dislocation of the shoulder after intramuscular injection antibiotic(s) is rare and this conditon was limit described in literature. Our purposes were: (1) determining the clinical symptoms, X-ray and CT findings; and (2) determining the indications and the surgical technique and evaluation of the surgical result. Material and methods: 62 children (29 females, 33 males) aged from 4 to 16 years were included. Clinical and X- ray findings were analysed for anterosuperior subluxation or dislocation of humeral head. The patients were operated to release of origin or insretion of the mild Deltoid muscle or Z plasty of this one. Surgical procedures provided good result in 75.3 percent, fair in 24.7 percent and there were no infection or neuromuscular complication in these cases. Conclusions: This condition always resulted from repeated Deltoid intramuscular injection. The surgical treatment with resection of fibrous portions constantly gives relief of symptoms and provides good function.
Shoulder Dislocation, Injections, Intramuscular, Child

No abstract available.
Abscess* ; Injections, Intramuscular* ; Pseudomonas aeruginosa* ; Pseudomonas*

Esfenvalerate is a kind of commonly used highly effective pyrethroid insecticide. It is common for people who are poisoned by contact or misuse, but rarely reported for people who are poisoned by intramuscular injection. This paper reports a case of intramuscular injection of esfenvalerate in the Department of Infection, West China Hospital of Sichuan University in November 2021. The patient was intramuscularly injected with about 20 ml of esfenvalerate, inducing the sense of swelling and tingling, degeneration and necrosis of striated muscle tissue at the injection site, also liver function damage and other manifestations. The patient was discharged from hospital after rehydration, accelerating poison metabolism, anti-infection, liver protection and local puncture.
Humans ; Insecticides ; Injections, Intramuscular ; Pyrethrins ; Nitriles/metabolism*

PURPOSE: We evaluated the effectiveness of tamsulosin on the expectant treatment for the patients suffering with lower ureteral stones. MATERIALS AND METHODS: A total of 67 patients with stones less than 5mm that were located in the lower ureter were enrolled in the study. The patients were randomly divided into two groups. Group 1 (n=32) received 20mg caroverine (a spasmolytic drug) orally three time a day. Group 2 (n=35) received 0.2mg tamsulosin orally one time a day. The treatment was continued until expulsion of stone or to a maximum of 28 days. All patients were allowed 30mg ketorolac trimethamine intramuscular injections on demand. We compared the two groups for stone size, the expulsion rate, the time to expulsion and use of analgesics. RESULTS: The average stone size was 4.3+/-0.61mm for group 1 and 4.4+/-0.51mm for group 2. No statistical difference between two groups was found for stone size, age and sexual distribution. The expulsion rate was significantly higher in group 2 (82.8%), compared with group 1 (53.1%) (p=0.002). The mean expulsion time was 8.3 days for group 1 and 4.6 days for group 2 (p<0.0001). The average number of intramuscular analgesic injections was 3.9 for group 1 and 1.1 for group 2 (p<0.0001). CONCLUSIONS: Tamsulosin was proved to be effective and safe, as demonstrated by the increased stone expulsion rate, the decreased expulsion time and the reduced use of pain control in the expectant treatment of the lower ureter stones.
Analgesics ; Humans ; Injections, Intramuscular ; Ketorolac ; Ureter* ; Urinary Calculi

Nicolau syndrome is a rare adverse reaction of the skin at the site of intramuscular drug injection, and has largely unidentified pathogenesis. It consists of the development of an acute, severe pain and a localized erythematous rash during intramuscular injection leading to cutaneous, subcutaneous and even muscular necrosis. We report a case of a 55-year-old woman who presented with a painful skin necrosis in her buttocks following an intramuscular diclofenac-beta-dimethyl-aminoethanol injection.
Buttocks ; Exanthema ; Female ; Humans ; Injections, Intramuscular ; Middle Aged ; Necrosis ; Skin

BACKGROUND: Although postoperative back pain has been reported to occur, as a frequent complication of anesthesia and surgery, it is usually mild and self-limited. However, we experienced cases of uncontrolled postoperative back pain in patients even after IV-PCA administration. These patients' back pain was relieved by the traditional diclofenac sodium intramuscular injection, so we evaluated the efficacy of diclofenac sodium on uncontrolled postoperative back pain by IV-PCA. METHODS: We studied 16 patients who complained of postoperative back pain even with IV-PCA for postoperative pain control. When NRS pain score was above 5, the patients were treated with a diclofenac sodium 75 mg intramuscular injection. Postoperative back pain and operation site pain was measured by NRS before and after diclofenac sodium injection. RESULTS: There was a significant decrease in the pain score of postoperative back pain after diclofenac sodium injection without a dramatic improvement of operation site pain. CONCLUSIONS: Diclofenac sodium plays a useful role in the control of acute postoperative back pain.
Anesthesia ; Back Pain* ; Diclofenac* ; Humans ; Injections, Intramuscular ; Pain, Postoperative

PURPOSE: We evaluates if the administration of tamsulosin increases the efficacy of extracorporeal shock wave lithotripsy (ESWL) in the patients with upper ureteral stones and if this decreased the use of analgesic drugs after the procedure. MATERIALS AND METHODS: A total of 45 patients with stones 6-12mm in size that were located in the upper ureter were enrolled in the study. The patients were randomly divided into two groups. Group 1 (n=23) received 3 times a day oral treatment of 20mg caroverine (a spasmolytic drug). Group 2 (n=22) received one time a day oral therapy of 0.2mg tamsulosin. All the patients received oral treatment for 14 days. Both groups of patients were allowed to use 30mg ketorolac trimethamine intramuscular injections on demand. The endpoint of the study was the stone expulsion rate, the use of analgesics and the drug adverse effects during treatment. RESULTS: The average stone size was 7.9+/-2.79mm for group 1 and 8.2+/-3.14mm for group 2. No statistical difference between the two groups was found for the stone size, age and gender distribution. The expulsion rate was significantly higher in group 2 (90.9%) compared with group 1 (65.2%) (p=0.038). The average number of pain control injections was 0.78 for group 1 and 0.23 for group 2, and there was a statistically significant difference between the two groups (p=0.042). CONCLUSIONS: The use of tamsulosin proved to be effective and safe, as demonstrated by the increased stone expulsion rate and the lesser need for pain control than that when using just a spasmolytic drug for ESWL of upper ureter stones.
Analgesics ; Humans ; Injections, Intramuscular ; Ketorolac ; Lithotripsy* ; Shock* ; Ureter* ; Urinary Calculi