No abstract available.
Genome, Human* ; Human Genome Project* ; Humans ; Humans*

No abstract available.
Genome, Human* ; Humans ; Humans*

No abstract available.
Human Growth Hormone* ; Humans*

No abstract available.
Human Rights ; Humans

OBJECTIVETo study on visible display of Meridian on the dummy human body.

METHODSTube model-building method and computer technique were used, and data came from Voxel-Man dummy human body development platform.

RESULTSThe visual effect of re-building Meridian is very good and it can display the different layers of anatomic structures on the Meridian lines.

CONCLUSIONThe visible display of Meridian on the dummy human body is preliminary realized, which provides data carriers for establishing the platform of Meridian study.

Human Body ; Humans

The use of cosmetics in the crowd has the long-term characteristics. The adverse reactions of cosmetics reported in other country in the world suggest that human patch tests and short-term human using test may not be sufficient to evaluate the safety of high-risk new cosmetic raw ingredients, and long-term human using test should be conducted for evaluation. Therefore, this article reviews the key factors that affect long-term human trial trials, such as site of use, single-use amount, frequency of use, duration of use, and subject conditions, providing supportive evidence for standardized safety evaluation standards for long-term human using test of cosmetics.
Humans ; Cosmetics ; Human Experimentation

The use of cosmetics in the crowd has the long-term characteristics. The adverse reactions of cosmetics reported in other country in the world suggest that human patch tests and short-term human using test may not be sufficient to evaluate the safety of high-risk new cosmetic raw ingredients, and long-term human using test should be conducted for evaluation. Therefore, this article reviews the key factors that affect long-term human trial trials, such as site of use, single-use amount, frequency of use, duration of use, and subject conditions, providing supportive evidence for standardized safety evaluation standards for long-term human using test of cosmetics.
Humans ; Cosmetics ; Human Experimentation

INTRODUCTION: Gadget use with its diverse range of functions from communication to navigation and
entertainment, has brought increasing concerns about its effects on psychological health. Despite
growing evidence on its effect among children, its effect on the adolescent age group, particularly on
the socio-emotional dimension remains uncertain.

METHOD: An analytical cross-sectional study was done to identify a possible association between duration
of gadget use and socio-emotional difficulties of an adolescent. A cluster sample of junior high school
students aged 13-17 years old from four selected private schools were invited to answer the Strengths
and Difficulties Questionnaire (SDQ) to measure socio-emotional difficulties and provide information on
the type and duration of gadget use. Scores derived from the SDQ were classified as normal, borderline
and abnormal based on the questionnaire's scoring guide. Association between duration of gadget use
and strengths and difficulties was tested using chi-square, controlling for sex and age groups.

RESULTS: Majority of the 315 respondents had normal scores on the strengths and difficulties sub-scales.
Regardless of the duration of gadget use, majority of the respondents had normal prosocial behavior
and likewise scored normal on all dimensions of the Difficulties subscale. There was no significant
association between duration of gadget use and Strength (p = 0.47) and Difficulties scores (p = 0.35).
Stratifying by sex and age groups likewise resulted in insignificant associations (p > 0.05). Those with
prolonged gadget use were 1.68 times more likely to have abnormal scores on the Difficulties subscale
compared with those with normal gadget use but the association was not significant (95% CI 0.82, 3.34).

CONCLUSION: There was no significant association between duration of gadget use and socio-emotional
difficulties of adolescents in selected private schools, controlling for sex and age groups.

INTRODUCTION: There is a consistent increase in the interest and demand for non-invasive modalities to
improve facial skin laxity and rhytides. Monopolar radiofrequency is one of such non-invasive modalities.
This systematic review aimed to determine the efficacy and safety of monopolar radiofrequency in
improving facial rhytides and skin laxity.

METHODS: Clinical studies that assessed the efficacy of monopolar radiofrequency to address clinically
observable facial rhytides and skin laxity were included. Outcome measures included improvement
in rhytides and skin laxity as documented by patient satisfaction scores, and investigator and third-person
observer ratings based on clinical photographs and clinical scales.

RESULTS: Three studies involving 29 participants were included in this review. All studies reported 25-
50% improvement in facial rhytides and skin laxity. Participants from the three studies were satisfied
with the results. Transient erythema was reported in several patients.

CONCLUSION: Monopolar radiofrequency appears to be beneficial and safe for patients with facial
rhytides and skin laxity. However, the evidence is inconclusive due to problems in the methodological
quality of each trial and the heterogeneity of the studies included in this review.