With the 2015 deadline for fast approaching the millennium development goals ( MDGs) , attention has turned to what should follow.The post-2015 development agenda is due to be adopted by the world leaders in a high-level summit which was held in New York in September 2015 .This paper summarizes the health-related MDGs progress and suggestions, describes the negotiations process on the health-related post-2015 development agenda, dis-cusses the proposed framework of the sustainable development goals and its indicators, and then provides some sug-gestions on the Chinese participation in the post-2015 development agenda as well as in the upcoming high-level sum-mit.

Being the kernel of functional gene group,the field of protein group becomes the focal point of life science research in 21th century.SELDI,which is based on the combination of chip technology and mass spectrum technology,has become the main method for filtrating tumor marker in clinical research.This paper introduces the basic principle of SELDI system and summarizes the application of SELDI to tumor marker detection in galactophore cancer.

BACKGROUND: Currently, therapies for spinal cord injury include steroid pulse therapy, surgical decompression and stem cel therapy. A lot of work has been focused on stem cel therapy for spinal cord injury which has become a hot spot. OBJECTIVE: To summarize the research status and progress in induced pluripotent stem cells for treatment of spinal cord injury. METHODS: A computer-based online search of PubMed (1980-01/2011-11) was performed for articles in English using the keywords of “spine injury, induced pluripotent stem cells, IPS”RESULTS AND CONCLUSION: A total of 35 articles were included in result analysis, in which, stem cel therapy for treatment of spinal cord injury is agreed or supported. Induced pluripotent stem cells are isolated directly from the body, which solves ethical and moral issues in the transplantation of stem cells, meanwhile avoids al ograft rejection and also provides a large source of cells. Stem cel therapy for spinal cord injury is widely used in animal experiments but few in clinical application. However, stem cel therapy has a good effect in the animal experiments, and shows a higher safety. The existing problems of induced pluripotent stem cells to treat spinal cord injury mainly include immature differentiating method of induced pluripotent stem cells and more complications. Therefore, induced differentiation and security of induced pluripotent stem cells for treatment of spinal cord injury wil become a research key.

Objective To evaluate the effects of exercise therapy in the treatment of hemiplegia following cerebral hemorrhage. Methods Activities of daily living(ADL) scoring and Fugl Meyer test were performed in 46 patients with hemiplegia following cerebral hemorrhage undergoing exercise therapy before and after treatment. Results Significant improvement of ADL, upper extremity function, and balance and walking abilities was found after treatment( P

Objective:To explore the therapeutic effect of the extraction of bone-melon injection for the earlier fracture.Method:100 patients with early fracture were divided into two groups.50 cases in the treatment group used the extraction of the bone-melon injection and 50 cases in the controlled group used compound ossotide injections.Their curative effects were judged according to their healing time,level of relieving pain and functional recovery condition.Result: The patients in the treatment group healed earlier(P

Objective To evaluate the safety of endoscopic ligation of gastric and colic full-thickness wall with nylon loops.Methods Endoscopic ligation of full gastric and colic wall with detachable nylon loops, assisted by laparotomy, were performed in 4 dogs.Ligation healing was assessed on 3, 7, 10and 17 days after the procedure.Results All animals recovered after the procedure, without any clinical signs of infection or hemorrhage.Postoperative examination did not reveal gastric or colonic perforation, or local abscess.Loop ligature showed ulcer-like lesion.Histopathology revealed muscularis propria disruption, granulation tissue bridging the site of ligation and formation of scar tissue.Regenerative mucosa coyered the surface of the ligature completely 17 days after the operation.Conclusion Endoscopic ligation of gastric and colic full-thickness wall with detachable nylon loops is safe.Its application can be extended to other fields.

Aged ; Antigens, CD20 ; metabolism ; Humans ; Leukocyte Common Antigens ; metabolism ; Lymphoma, B-Cell ; complications ; metabolism ; pathology ; surgery ; Male ; Prostate ; pathology ; Prostatectomy ; Prostatic Hyperplasia ; complications ; metabolism ; pathology ; surgery

Objective To investigate surgical techniques for tibial plateau fractures involving the posterior column and the corresponding clinical effect.Methods From March 2009 to January 2012,32 patients with tibial plateau fracture involving the posterior column underwent surgical treatment in our hospital,including 21 males and 11 females,aged from 23 to 60 years (average,40.4 years).There were 30 cases of closed fracture and 2 cases of open fracture.Two patients combined with anterior cruciate ligament avulsion fracture,and 3 patients with posterior cruciate ligament avulsion fracture.Posterolateral and anteromedial approaches were used in 6 patients with posterolateral and medial columns fracture.Posteromedial and anterolateral approaches were used in 7 patients with posteromedial,medial and lateral columns fracture; a small anteromedial incision was added in 2 of them.Posteromedial and anterolateral approaches were used in 11 patients with posteromedial and lateral columns fracture.Posteromedial and posterolateral approaches were used in 2 patients with posteromedial and posterolateral columns fracture,while a single posteromedial approach was used in another patient with same fracture.Posteromedial and anterolateral approaches were used in 3 patients with posteromedial,posterolateral and lateral columns fracture,while posterolateral and anterolateral approaches were used in other 2 patients with same fracture.Results All patients obtained satisfactory exposure and reduction.They were followed up for 5 to 24 months (average,10.7 months).The average bone union time was 15.9 weeks,and the average time from operation to full weight-bearing was 18.1 weeks.The average range of motion of knee was 113.3°.According to HSS (Hospital for Special Surgery) score,the results were excellent in 22 cases,good in 6 cases,fair in 3 cases and bad in 1 case; the total excellent and good rate was 87.5％.Conclusion For tibial plateau fractures involving posterior column,satisfactory reduction and fixation can be obtained via posteromedial and posterolateral approaches which have many advantages such as earlier functional exercise,fewer complications and excellent clinical results.

Objective To investigate the roles of endoscopic biopsy and third ventriculostomy in the diagnosis and treatment of pineal region tumors in children. Methods Endoscopic biopsy and third ventriculostomy were performed in 9 pediatric patients with pineal region tumors. Results Successful third ventriculostomy, confirmed by MRI, was performed in 9 cases of children with obstructive hydrocephalus. No complications were found in all patients. Conclusion Endoscopic biopsy and third ventriculostomy are effective neuroendoscopic procedures in minimally invasive preferential management of pineal region tumors.

Objective to research the mechanical style(compressive or tensile force)of the key site of brain tissue in brain deceleration impact.Method a transparent physical brain model with air bubbles was built and loaded on an upright brain decaler ation impacting expedmentel platform.Then,the moveable platform was made a free fall from a height of 400mm and impacted on the fixed platform,and the whole deceleration impacting process was recorded by a high-speed video camera.Using the serial pictures analyzing Software,the length change of the long ads(vertical to the impacting direction)and the short axis(in the impacting di-rection)of the air bubbles were analyzed and calculated.Result the length change of the long axis of air bub-ble with in site coup was smallerthan the absolute value of that of the short axis;while with the air bubble in the contrecoup site,the length change of the long axis was bigger than the absolute value of the short axis.Conclusions the results showed that the air bubble in the coup site mainly suffered from the tensile force vertical to the impacting direction and the air bubble in the contrecoup site mainly suffered from the compres-sive force in the impacting direction.Since the propeny of tensile resistance of the brain tissue is inferior to the property of compressive resistance of the brain tissue, the injury is often easier to occur in the contrecoup site than in coup site. The results were of significance to the research of biomechanical mechanism, diagnosis and prevention of the brain deceleration impacting injury.