1.MR Imaging Features of Fibrocystic Breast Disease
Hui XU ; Wenxiao JIA ; Yan LIU
Journal of Practical Radiology 2010;26(2):246-250
Objective To analyze the MRI features of fibrocystic breast disease (FBD). Methods 39 patients with pathologically proven FBD were retrospectively reviewed. The imaging protocol consisted of pro-contrast imagings and bilateral breast volume im-aging for breast assessme NT(VIBRANT). MRI features were interpreted based on the morphologic and enhancement kinetic de-scriptors defined on ACR DIRADS-MRI lexicon. Results There were 3 types on ACR BI-RADS-MRI lexicon in FBD,including 13 focal mass-type showing malignant enhancement kinetic pattern mostly;15 cyst-type with non-enhancement or mild enhance-ment,of them,1 case with periductal mastiffs showing strong enhancement and rapid up-slope and wash-out mimicking a breast cancer. 6 non-mass type usually showing benign enhancement kinetic pattern. In 5 patients,MRI did not show definite abnormal evi-dence. Conclusion MRI is of significant value in diagnosing FBD.
4.Characteristics of vena cava connection in patients with asplenia
Jianpeng, WANG ; Yan, SUN ; Hui, LI ; Xin, QUAN ; Hui, XU ; Xiaoni, LI ; Jun, YAN
Chinese Journal of Medical Ultrasound (Electronic Edition) 2015;(2):160-164
Objective To investigate the characteristics of vena cava connection in patients with asplenia syndrome diagnosed by ultrasound. Methods From October 2009 to February 2014, 49 patients with asplenia syndrome diagnosed in Fuwai Hospital by ultrasound were included in this study. The characteristics and percentage of varied types of anomalous connection of vena cava and pulmonary vena were analyzed. Results Thirty patients (61.2%) had bilateral superior vena cavies. In these cases, right vena cava was drainage into right atrium (or the right side of the single atrium), while left superior vena cava into left atrium (or the left side of the single atrium). For hepatic vein, drainage into inferior vena cava were found in 25 patients (53.2%), into left atrium (or the left single of the single atrium) in 1 patient (2.1%), into right atrium (or the right side of the single atrium) in 3 patients (6.3%), into both right and left atrium in 5 patients (10.2%) and into the middle of the single atrium in 1 patient (2.1%). For inferior vena cava, drainage into left atrium (or left side of the single atrium) were found in18 patients (36.2%), into right atrium (or right side of the single atrium) in 24 patients (51.1%) and into the middle of the single atrium in 1patient (2%). Total anomalous pulmonary venous drainage occurred in 20 patients (40.2%) and partially anomalous pulmonary venous drainage in 8 patients (16.3%). Conclusion Asplenia syndrome is frequently accompanied with anomalous vena cava and pulmonary venous drainage.
5.Selection points by up-down cross method for ankle sprain.
Cheng LI ; Wei-Hui LU ; Jing-Yan XU
Chinese Acupuncture & Moxibustion 2011;31(10):918-918
Acupuncture Points
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Acupuncture Therapy
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Adolescent
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Adult
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Ankle Injuries
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therapy
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Female
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Humans
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Male
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Sprains and Strains
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therapy
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Treatment Outcome
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Young Adult
6.Highly sensitive Immuno-PCR assay for the detection of the circulating antigens in trichinellosis
Hui LI ; Bianli XU ; Xudong ZHAO ; Yan DENG ; Ximeng LIN
Chinese Journal of Zoonoses 2005;(9):769-775
A highly sensitive immuno-PCR assay based on sandwich ELISA and PCR was developed to detect the circulating antigen in trichinellosis. Antigens were purified from the muscle larvae of Trichinella spiralis, and the myeloma cells were fused with spenocytes immunized with T. spiralis antigens to product the specific monoclonal antibodies. Indirect ELISA was used to select the antibody-secreting hybrodoma cells. By this method of procedure, monoclonal antibody F4C6 against the T. spiralis ES antigen was obtained, which was used as the indicator antibody, while the rabbit polyclonal antibodies against T. spiralis were to be used as capturing antibodies. The plasmid Bluecript Ⅱ KS was amplified by PCR with biotin-labeled primer M13-20, and thus the biotin-labeled DNA was obtained. Both the second antibody and DNA labeled with biotin were to be linked with 100 ng/ml avidin. The whole procedures of assay consisted of two steps, in which the circulating antigens were captured by monoclonal antibody through sandwich ELISA in the first step, and the DNA linked by monoclonal antibody was amplified by PCR in the second step. The sensitivity of this method was compared with that of the ELISA assay. It was found that the measuring ranges to detect the circulating antigens in trichinellosis were 50 pg/L to 0.005 pg/L for the immuno-PCR assay, and 5 μg/L to 0.05 μg/L for ELISA assay, the former was quite higher than that of the latter. It is evident that this method is highly sensitive for the detection of circulating antigens in trichinellosis.
7.The role of human papillomavirus in the pathogenesis of pterygium
Hui-yan, XU ; Song, SUN ; Ting-ting, ZHU
Chinese Journal of Experimental Ophthalmology 2011;29(12):1102-1105
Background The pathogenesis of pterygium has been in the study.Relative molecular biology study showed that pterygium is a tumor-like lesion,and based on overseas literatures,human papillomavirus (HPV) is positively expressed in 100% patients with pterygium in some region.However,if this result is suitable for Chinese patients is unclear.Objective This study was to identify the role of human HPV in the pathogenesis of pterygia in Wuxi area.Methods Forty-eight pterygium specimens including 7 recurrent pterygia and 41 primary pterygia were collected during the operation,and these patients were from Wuxi area.Two cervical carcinoma specimens and 2 conjunctiva specimens from normal donors were obtained as positive control and negative control respectively.The fluorescent quantitative polymerase chain reaction (FQ-PCR) was used to detect HPV DNA of specimens.Results The amplified curves of HPV 6,11 of pterygium specimens,cervical carcinoma specimens and normal specimens were all below the positive quality control curve,but the amplified curves of HPV16,18 were above the quality control curve in cervical carcinoma specimens; while those of pterygium specimens and normal conjunctival specimens were all below the quality control curve.HPV16/18 was identified in 2 cervical carcinoma specimens,but no HPV6/11 was detected in 2 cervical carcinoma specimens.However,HPV DNA expression in primary and recurrent pterygias were absent.Conclusions According to these results,HPV is not the primary cause for the pathogenesis of pterygium in Wuxi region.
8.Bacteria Contens in Air of Tuberculosis Wads Before and After Use:A Comparative Study
Xiufeng ZHANG ; Hui ZHAO ; Huiquan XU ; Xiuling DU ; Ling YAN
Chinese Journal of Nosocomiology 2009;0(15):-
OBJECTIVE To detect the condition of bacteria of the air in wards of our hospital in order to reduce the possibility of air spread. METHODS Ten tuberculosis wards were chosen at random for study.Detected the bacteria content of the air in wards used before and after respectively and analysed the results. RESULTS The average of backgroud bacteria was 164 CFU/m 3 before the wards were used.Two years later,the average of bacteria increased to 682 CFU/m 3.The ratio was 1∶3:2 on average.There were significant differences between them. CONCLUSIONS Humen are the main facters that make the air polluted in these wards.The bacteria content will decline by good environment cleaning sanitation,ventilation and strengthening steriling management.Infection will decline in the hospital.
9.Construction of double eyelid with incision of palpebral margin
Hui ZHANG ; Ping HAO ; Kai XU ; Yan SHANG ; Qian LI
Chinese Journal of Medical Aesthetics and Cosmetology 2008;14(2):101-103
Objective To evaluate results of double eyelid operations with different incisions.Methods 100 patientswere selected randomly from out-patients that accepted double eyelid operation.Half of them were objected to double eyelid operation through a palpebral marginal incision.Incision was designed along the palpebral margin,close to boots of eyelashes.Most of the subcutaneous tissues was cut and removed,and then dermis and tarsal plate were fixed with 5 stitches of suture.About 1-3 mm wide of skin along superior margin was removed reasonably.In another 50 cases.double eyelid operation was performed with conventional incision.Incision was designed 6-8 mm far from the palpebral margin.Most of the subcutaneous tissues was removed.and then dermis and tarsal plate were fixed with 5 stitches of suture.Results Postoperative results were evaluated 5 days and 1 month after operation respectively.Postoperative double eyelid shapes were all satisfled in two groups.Swollen eyedids and scar were more inconspicuous in the cases with the palpebral-marginal incision without impairment on eyelashes.Conclusion Compared with double eyelid operation with conventional incision,blepharoplasty with palpebral margin incision has the same results but with lighter impairment,milder hydropsia and more inconspicuous scar.The key point of this procedure is the fixation of dermis and tarsal plate,keeping a good radian of double eyelid line.
10.Clinicopathological and molecular genetic characteristics of childhood diffuse large B cell lymphoma.
Hui HUANG ; Wen-ping YANG ; Hong-yan XU
Chinese Journal of Oncology 2012;34(3):209-211
Adolescent
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Antigens, CD20
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metabolism
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Antineoplastic Combined Chemotherapy Protocols
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therapeutic use
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Burkitt Lymphoma
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drug therapy
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metabolism
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pathology
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surgery
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Child
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Child, Preschool
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Cyclophosphamide
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therapeutic use
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DNA-Binding Proteins
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metabolism
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Doxorubicin
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therapeutic use
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Female
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Follow-Up Studies
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Genes, myc
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Humans
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Hyaluronan Receptors
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metabolism
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Ki-67 Antigen
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metabolism
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Lymphoma, Large B-Cell, Diffuse
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drug therapy
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genetics
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metabolism
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pathology
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surgery
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Male
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Neoplasm Staging
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Neprilysin
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metabolism
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Peritoneal Neoplasms
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drug therapy
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genetics
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metabolism
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pathology
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surgery
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Prednisone
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therapeutic use
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Proto-Oncogene Proteins c-bcl-2
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metabolism
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Proto-Oncogene Proteins c-bcl-6
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Stomach Neoplasms
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drug therapy
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genetics
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metabolism
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pathology
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surgery
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Translocation, Genetic
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Vincristine
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therapeutic use