1.Analysis of Clinical Control of Type 2 Diabetes in 7356 Outpatients
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(09):-
Objective To study the current status of clinical control of outpatients with type 2 diabetes mellitus,and to discuss the factors influencing on disease control. Methods According to the clinical targets recommended by Asian-Pacific Type 2 Diabetes Policy Group,we calculated the success rates of blood glucose,lipid profile,blood pressure and body mass index(BMI) of patients who hospitalized in our department for more than one year(group A,n=7 356), and compared these results with the corresponding rates calculated based on the earlier database(group B,n=1 084).The success rates of metabolic indexes of patients who insisted on hospitalizing monthly(group C,(n=1 367))were calculated.Besides,the factors influencing disease control were discussed through questionnaire.(Results)There were 7356 patients in group A,and the success rates of HbA1c,blood pressure,blood lipid profile and BMI were 30%,25.8%,32.6% ~ 81.3% and 50.9%,respectively.Except for the parameter of high-density lipoprotein,the other rates were higher than the responding ones of group B.There were 1367 patients in group C, and the success rates of main metabolic indexes were higher than those of group A and B.The result of the questionnaire indicated that poor understanding of diatetes,lack of health education,and relative scarcity of diplomate were the main factors that influenced the disease control. Conclusion The disease control of most of the type 2 patients with diabetes are far from satisfaction.The application of scientific disease care system is effective for improving the disease control.
2.Exploring of the Diabetes Care Model
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(09):-
Objective To explore the new diabetes care model. Methods A new flow for diabetic outpatient to visit the doctor, a uniform system for diagnosis,treatment and follow-up,an electronic medical record system,and a long-term diabetes education which mainly delighted patients on "diabetic self-management" were established.(Results)The service quality from the medical staff were improved markedly.Database including the clinical data of 10 020 patients and 2 563 serum samples and DNA samples were built up.A set of diabetes care model that laid the foundation for clinical and research work was formed. Conclusion Long-term education for patients with diabetes mellitus constitues the basic and important part of diabetic care model.The application of computer in diabetic care is the effective means.It is necessary to establish a uniform scheme for diagnosis,treatment and follow-up for the patients,and the improvement of medical staff's professional making ensures the successful implementation of the model.The combination of clinical practice and research work propels the development of scientific management model for patients with diabetes mellitus.
5.Methods of trasferral of tissues and cells on slices.
Chinese Journal of Pathology 2008;37(5):348-349
Adoptive Transfer
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methods
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trends
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Cells
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pathology
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Cells, Cultured
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pathology
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Humans
6.CD30-positive of diffuse large B-cell lymphoma of small intestine co-existing with tubular adenocarcinoma of rectum: report of a case.
Chinese Journal of Pathology 2007;36(9):641-642
Adenocarcinoma
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metabolism
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pathology
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surgery
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Aged
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Humans
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Intestinal Neoplasms
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metabolism
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pathology
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surgery
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Intestine, Small
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Ki-1 Antigen
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metabolism
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Lymphoma, Large B-Cell, Diffuse
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metabolism
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pathology
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surgery
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Male
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Neoplasms, Multiple Primary
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metabolism
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pathology
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surgery
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Rectal Neoplasms
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metabolism
;
pathology
;
surgery
7.The use of home-made blenderized diet in nutritional support in old comatose patients
Limei HUA ; Xiaojun LIU ; Wei GAO
Parenteral & Enteral Nutrition 1997;0(02):-
Objective: To observe the effect of home-made blenderized diet on nutritional support in old comatose patients.Methods: Sixty-three old comatose patients were fed with home-made blenderized diet by nosal gastric feeding.Triceps skinfolds were measured every month.The serum levels of albumin,pre-albumin,total number of lymph cells and hemoglobin were analysed every month.Results: No side effects of abdominal pain,dearrhea,nausea and vomiting were observed in the fed patients.The states of nutrition(such as triceps skinfolds,albumin,pre-albumin,total number of lymph cells and hemoglobin) were improved significantly after home-made blenderized diet.Conclusion: The home-made blenderized diet can support the old comatose patients effectively.
8.46 cases of off-pump CABG and plication of left ventricular aneurysm
Rui LIU ; Chengxiong GU ; Hua WEI
Chinese Journal of Thoracic and Cardiovascular Surgery 2003;0(04):-
Objective To review the experience of OPCAB and plication of left ventricular aneurysm. Methods Without cardiopulmonary bypass, heparin was given at 1.0~1.5 mg/kg.The 2-0 Surgipro 843 sutures were placed across the base of aneurysm using a strip of teflon felt on either side. The suture line was oriented to reconstruct a relatively normal left ventricular contour. Concurrent CABG was performed. Results 46 cases were reviewed. Left internal mammary artery (LIMA) grafts to the LAD were performed in 39 cases, off-pump with cardiopulmonary bypass in 3, IABP were used in 2. One patient died of left ventricular dysfunction. The other patients had no new myocardial infarctions and were discharged 10 to 14 postoperative days. Conclusion OPCAB and plication of left ventricular aneurysm could obviously decrease the risk of cardiac rupture and avoid the complications of cardiopulmonary bypass.
9.Applying ROI Interbody Fusion Cage for Anterior Cervical Intervertebral Disc Resection Arthrodesis Treat Early Cervical Degenerative Disease
Jiang HUA ; Fucun LIU ; Wei WANG
Journal of Zhejiang Chinese Medical University 2013;(7):877-880
[Objective] The objective of the study was to determine the clinical and radiological outcomes of cervical interbody fusion using ROI cages. [Methods] Patients showing degenerative cervical mono- or bi-level pathology were prospectively included. Using AP and lateral radiographs, segmental height of the treated segments was determined quantitatively. Cage characteristics were described qualitatively. Clinical data such as the neck disability in-dex(NDI), numeric rating scale(NRS) were col ected at al time points .[Results] The scores of NDI, NRS were decreased gradual y, and stable after half year;but they were respectively reduced to 8.64 and 1.57 from 23.32 and 8.93, with difference of statistical meaning. The intervertebral angle increased af-ter operation, then decreased gradual y and was stable after half year, was 3.6 °after 1 year. The intervertebral height was maximum after operation, then re-duced gradual y, and was 5.32mm or so after 1 year. 16 patients were al cured after 1 year, with short fusion rate reaching 100%. [Conclusions] The clini-cal and radiological short-term outcome of anterior cervical discectomy and fusion using ROI cage are excel ent.
10.Advances in the targeting ATP-binding cassette transporters to overcome tumor multi-drug resistance.
Ning WEI ; Hua SUN ; Gengtau LIU
Acta Pharmaceutica Sinica 2010;45(10):1205-11
ATP-binding cassette (ABC) transporters are a family of proteins that mediate multi-drug resistance (MDR) via ATP-dependent drug efflux pumps. Abnormally expression and function would result in tumor MDR. That is the most important mechanism of MDR. The inhibition of ABC transporters as a strategy to reverse MDR in cancer has been studied extensively. In this review, we reviewed the structure and function of ABC transporters, and focused on the research advances in the mechanism of tumors MDR mediated by ABC transporters and the development of their modulators and reversal strategies.