1.The variation of N400 event-related potentials during language cognition of different paradigms in stroke patients
Chinese Journal of Physical Medicine and Rehabilitation 2013;(1):5-8
Objective To explore the cognition processes of language in stroke patients by characterizing the differences between the event-related potentials (ERPs) N400 evoked bypicture-word andsentence-wordparadigms.Methods Twenty patients with a single brain lesion resulting from a first episode of stroke were tested along with 20 normal controls.Their N400 ERPs were tested using pictures and sentences as activating stimuli and phrases composed of nouns and verbs as the target stimuli.The N400 potentials were recorded from electrodes located at Fz,Pz,T3 and T4 positions of the International 10-20 system.The N400 latencies and amplitudes and the behavioral responses of the experimental and control groups were compared.Results The latencies were longer and the amplitudes were lower in response to sentence activation than to picture activation.The differences in terms of amplitude were the greatest with N400 recorded from Pz.The responses to the target stimuli were not significantly different with regard to the types of stimuli and recording location.The average response time was longer and the error rate was higher in response to sentence activation than to picture activation.Conclusion Multiple accesses,activating stimuli and integrating processes are involved in language cognition.The brain is more sensitive and accurate in response to picture stimuli in language cognition.The response to sentence stimuli is slower,and the error rate is higher.This suggests that it is better to usc varied prime stimuli in teaching children languages.
5.Clinical Assessment of Chinese Recognition in Patients with Right Cerebral Hemisphere Lesion
Yanling XI ; Hua LI ; Jing HAN
Chinese Journal of Clinical Psychology 2000;0(04):-
Objective:TO provide theoretic evidence for Chinese rehabilitation training to study the characteristics of right hemisphere in recognizing Chinese and association between left and right cerebral hemispheres.Methods:102 cases up to the qualification,including 41 patients with right-hemisphere-lesion(RHL)、 31 patients with left-hemisphere-lesion(LHL) and 30 healthy individuals as control,were collected and tested with The Standardized Aphasia Battery in Chinese(ABC)、Writing-scopy of Chinese Character and Visual Spatial Structure-scopy.Results:14 aphasic patients,including 1 RHL and 13 LHLs,were found 11 of 72 patients had apparent reading disorder,including 7 LHLs with language reading disorder and 4 RHLs with neglect reading disorder;and 29 of 72 patients had apparent writing disorder,including 13 LHLs with language writing disorder and 16 RHLs among whom 9 cases had visual space writing disorder and 7 cases had language writing disorder;RHLs showed lighter listenning comprehension disorder than that of LHLs in the test.Conclusion:Right hemisphere is mainly involved in Chinese written language recognition and processing,and one of the most important reasons of reading and writing disorder is left side neglect、visual consciousness and spatial analysis dysfunction due to RHL.
6.Progress of Study on N400 Event-related Potentials in Languge Cognition
Jing HAN ; Hua LI ; Yanling XI
Chinese Journal of Clinical Psychology 2006;0(06):-
N400 as one of endogenic components in event-related potentials,which reflected the cognitive process of language in brain,has been more and more widely concerned.This article reviewed the discovery,the characteristics,the origins and the elicited methods of N400,summarized the investigations and point at issue on the cognitive process of language over the past several years,and explored the application foreground of N400 in the field of language cognition.
7.Studies on the antioxidative activities of extracts from Undaria pinnatifida in vitro
Hua HAN ; Songmei ZHAN ; Yantao HAN ; Jinhan LI ; Chunbo WANG
Chinese Journal of Marine Drugs 1994;0(03):-
Objective The antioxidative activities of extracts from Undaria pinnatifida in vitrowere tested. Methods Using the assay system of peroxide value (POV), diphenyl picryl-hydrazyl (DPPH), the antioxidative activities of various extracts were studied and comparedwith VE and VC. Results Different extracts from Undaria pinnatifida showed antioxidativeactivities, and petroleum ether extract showed the highest free radical scavenging efficiency.Conclusion petroleum ether extract has stronger antioxidative effect than others.
8.Application of health education guided by the trans-theoretical model on the training of the first ;aid in the high altitude troops
Hua LI ; Hao LU ; Ruijuan HAN ; Juan LI ; Xinhua ZHU
Chinese Journal of Practical Nursing 2017;33(3):161-164,165
Objective To study the application effect of health education guided by the theory of cross-theoretical model in the training of the first aid training in the basic units of the plateau. Methods Choosing 386 long-term presence of plateau soldiers, and divided them into the control group and the experimental group, the control group was educated by traditional method, in the experimental group, the health education was carried out with the trans-theoretical model, nursing experts gave them targeted intervention. The number of groups at each stage was analyzed in different stages, the same to examination results and pass rate. Results After 6 months of intervention, there was a significant improvement in the mastering of the battlefield Five emergency technology of the experimental group and the scores were better than those of the control group (P<0.05). Theoretical results showed that pass rate of the control group was 89.1%(172/193), the experimental group was 99.5%(192/193), the difference between the two groups was statistically significant (χ2=7.129, P=0.039). In the survey of technical operation, ventilation, hemostasis, bandaging, fixing and handling examination pass rate of the control group respectively were 88.1%(170/193), 89.1%(172/193), 89.1%(172/193), 88.1%(170/193), 88.6%(171/193), the experimental group were 99.5%(192/193), 97.9%(189/193), 99.5%(192/193), 96.9%(187/193), 97.4%(188/193), there were significant differences between the two groups (χ2=7.896-12.759, P=0.001-0.043). Conclusions Cross theoretical model has good effect on the application ofFiveemergency technology training in the high altitude troops battlefield, and can effectively improve the troops self- help and mutual aid capabilities, it is worthy of popularization and application.
9.Diagnosis value of expression of inserum macrophage inhibitory factor 1 combined with alpha-fetoprotein isoforms 3 in primary liver cancer
Yanhong LIU ; Sugui HAN ; Hongmei LIU ; Hua GAO ; Yuzhu LI
Cancer Research and Clinic 2013;25(11):742-744
Objective Study on the diagnosis value of expression of serum macrophage inhibitory factor 1 (MIC-1) combined with alpha-fetoprotein isoforms 3 (AFP-L3) in primary liver cancer detected by enzyme linked immunosorbent assay (ELISA).Methods MIC-1 and AFP-L3 concentrations were detected by ELISA from selected 116 patients of primary liver cancer.Results were compared both in combined and sigle detection.Results In primary liver cancer group AFP-L3 concentration [(127.12±51.43) ngmml] was significantly higher than that in normal control group [(27.11±7.26) ng/ml,P < 0.001].With AFP-L3 > 38.0 ng/ml as the critical value,the sensitivity was 85.34 % (99/116),specificity was 88.33 % (53/60) and the diagnostic accuracy was 86.36 % (152/176).In primary liver cancer group MIC-1 concentration [(3140.43±1138.23) pg/ml]was significantly higher than that in normal the control group [(701.88±302.34) pg/ml,P < 0.001],the sensitivity was 91.38 % (106/116),specificity was 85.00 % (51/60),the diagnostic accuracy was 89.20 %(157/176).The two combined detection sensitivity was 83.62 % (97/116),specificity was 91.67 % (55/60),diagnostic accuracy was 86.36 % (152/176).Conclusion MIC-1 combined with AFP-L3 concentration detection can improve the specificity of the diagnosis of primary liver cancer,which has certain clinical value.