1.Effects of Supplemented Wuling Sang on treatment of patients with primary hyperlipemia
Chinese Traditional Patent Medicine 1992;0(01):-
0.05). But the Wuling Sang could obviously decrease serum TG content than Simvastatin(P0.05). The adverse drug reactions were stomach discomfort(4 patiens in SWS) group, 5.71%), abdominal discomfort(2 patiens in Simvastatin group, 4.55% ) and sleeplessness(5 patiens in Simvastatin group, 11.4%) . CONCLUSION: The results show the TCM drug SWS is effective and softy on treating the patients with primary hyperlipemia.
3.Expression of cellular FLICE-inhibitory protein in peripheral blood and lesion of patients with lichen planus
Chinese Journal of Microbiology and Immunology 2009;29(3):221-223
Objective To investigate the expression and distribution of cellular FLICE( Fas-assoelated death domain-like interleukin-I β-converting enzyme-like)-inhibitory protein (c-FLIP) in peripheral blood and lesions of lichen planus patients. Methods Peripheral blood and skin samples were obtained from 30 patients with lichen planns and 20 normal controls. Flow cytometry was used to detect intracellular c-Fl,lP in peripheral T and B lymphocytes, and immunohistochemistry was used to examine the expression of c-FLIP in lesionai tissue. Results Based on the pesitivity rate of c-FLIP, there was a significant increase in T iymphocytes in lichen planus compared with normal controls(6.32%±1. 17% vs 2.28%±0.54%, P < 0.05 ), while no significant difference was found in B lymphocytes between two groups (0.78% ±0. 16% vs 0.69% ± 0. 18%, P >0. 05 ). The expression intensity of c-FLIP in keratinocytes was also higher in lichen planusthanthatinnormalcontrols ( 89.73%± 5.24% vs 121.58% ±7.93% ,P < 0. 01 ). Conclusion c-FLIP is highly expressed in lesions and peripheral T lymphocytes of patients with lichen planus, which suggests the possible involvement of c-FLIP in the proliferation of T lymphocytes in lichen planns.
4.Research progress of assessment of minimal residual disease in acute myeloid leukemia
Journal of Leukemia & Lymphoma 2013;22(5):318-320
Assessment of minimal residual disease (MRD) in acute myeloid leukemia (AML) patients is now possible by using updated methods including real-time quantitative PCR (RQ-PCR) for abnormal fusion transcripts and multiparameter flow cytometry (MFC) for detecting leukemia-associated phenotypes.Using these techniques,MRD analysis has shown value in terms of risk assessment,continued patient monitoring,and therapeutic decision-making.
5.Strategy of standardized nutritional support therapy in the perioperative period
Chinese Journal of Digestive Surgery 2015;14(5):358-360
In recent years,nutritional support therapy has been increasingly paid attention to scientific and reasonable using for patients.Based on the recent researches,the hot topics on the nutritional risk screening,nutritional status assessment and preoperative and postoperative nutritional support therapy were analyzed,and the strategies and progresses of nutritional support therapy for the postoperative critically ill patients,obese patients and short bowel syndromes or bowel failure patients were summarized,meanwhile,hot issues on the standardized nutritional support therapy in the perioperative period were explored in this article.
6.Clinical Observation 0n Treatment of Cervical Spondylotic Radiculopathy with Combined Electroacupuncture Tuina and Traction
Journal of Acupuncture and Tuina Science 2009;7(3):156-158
Objective:To observe the clinical effect of combined electroacupuncture,tuina and traction treating cervical spondylotic radiculopathy.Method:Depending on the orders of the patient's first visit,120 cases were randomized into a treatment group (60 cases),receiving electroacupuncture,tuina and traction treatment,and a control group (60 cases),receiving electroacupuncture and tuina treatment.The treatment was done once a day,and 5 times constitute one course of treatment.A 2-day interval is set between the courses.The therapeutic effect was evaluated after 6 courses of treatment.Result:The total effective rate and recovery rate in the treatment group were 93.3% and 61.7%,respectively,whereas that of the control group were 78.3% and 31.7%,respectively,showing a significant statistical difference.Conclusion:Combined acupuncture,tuina and traction worked well for cervical spondylotic radiculopathy.
7.Observation of effect of laser and intubation applied in recurrent nasolacrimal duct-blok
Chinese Journal of Primary Medicine and Pharmacy 2015;(15):2304-2306
Objective To observe the effect of laser and intubation applied in recurrent nasolacrimal duct-blok.Methods 116 cases of recurrent nasolacrimal duct-blok patients were selected and divided into the observation group and control group by random number table.Only laser was given in the control group,and intubation added in the observation group.All the cases were followed up more than 1 year,and the effects in both group were compared. Results There were 63 effective cases in the observation group,and efficacy rate was 83.33%.And 17 effective cases in the control group,efficacy rate was 41.56%.The efficacy rate in the observation group was higher than that in the control group (χ2 =31.915,P <0.05).There was no false passage in both groups after laser given.Conclusion The effect of laser combined with intubation was better than that of laser alone in recurrent nasolacrimal duct-blok treatment.It was valuable to refractory and recurrent nasolacrimal duct-blok treating.
8.Analysis on detection results of Mycoplasma pneumoniae and Chlamydia trachomatis in children with respiratory tract infection
International Journal of Laboratory Medicine 2015;(1):87-88
Objective To understand the detection situation of Mycoplasma pneumoniae (MP)and Chtamydia trachomatis (CT) in children with respiratory tract infection.Methods MP and CT were simultaneously measured by fluorogenic quantitative PCR in 1393 children patients with respiratory tract infection.Results The total detection rates of MP and CT were 30.4%,in which MP was 21 .8%,CT was 9.3% and MP complicating CT was 0.65%.In the season distribution,the detection rates of MP and CT were highest in summer.In the age distribution,the detection rate of MP in the over 3-year-old group was higher than that in the other age groups,the differences had statistical significance(P <0.05).The detection rate of CT in the less than 1-month-old group was higher than that in other age groups with statistical difference(P <0.05).Conclusion MP and CT are easy to be detected out in summer;MP is easy to be detected out in children over 3 years old than other age groups;MP is easy to be detected out in neonates than other age groups.Fluorogenic quantitative PCR is rapid,sensitive and highly specific for the diagnosis of MP and CT infec-tions.
9.Six Kinds of Yuping Feng Powder Combined with Eye Wash Method Clinical Observation on the Treatment of Allergic Conjunctivitis
Journal of Zhejiang Chinese Medical University 2014;(10):1188-1191
Objective] To observe the six taste of Yuping wind powder combined with eye wash method in the treatment of al ergic conjunctivitis AC and the clinical curative effect. [Methods] From 2008 January to 2014 June in our hospital, diagnosed with al ergic conjunctivitis in 60 patients(120 eyes), were randomly divided into three groups of 20 cases(40 eyes), had the local application of 2% Sodium Cromoglicate Eye Drops three times a day, treatment group with six kinds of Yuping Feng powder taken oral y combined with traditional Chinese medicine topical eye wash method, the control group 1 of six kinds of Yuping Feng powder taken oral y, two times a day, the control group 2 only topical eye, were treated and fol owed up for 4~6 weeks, the clinical efficacy of the three groups were compared, also the use of statistical methods for the two sets of data analysis and comparison. [Results] The treatment group and the 2 control groups total efficiency compared had a significant difference( P<0.01); the treatment group and the control group 1 of total efficiency had significant difference(P<0.05). [Conclusion] The six taste of Yuping Feng powder combined with traditional Chinese medicine eye wash method must be effective in treatment of al ergic conjunctivitis, worthy of promotion.
10.Vertebral pedicle screw fixationversus cross-segment pedicle screw fixation for thoracolumbar vertebral fracture and dislocation
Chinese Journal of Tissue Engineering Research 2015;(26):4169-4173
BACKGROUND:The clinical treatment of thoracolumbar fractures and dislocation of the patients can be treated with pedicle screw fixation through adjacent vertebral segments. With the increased incidence of disease, many problems were found such as fixator loosening and breakage. OBJECTIVE:To compare the effectiveness of vertebral pedicle screw fixation versus cross-segment pedicle screw fixation for thoracolumbar vertebral fracture and dislocation. METHODS:100 patients with thoracolumbar vertebral fracture and dislocation were chosen in the 474 Hospital of Chinese PLA from February 2013 to May 2014. The patients were randomly assigned to two groups (n=50). Patients in the control group were treated with cross-segment pedicle screw fixation, and those in the observation group were treated with the vertebral pedicle screw fixation. Parameters of imaging were compared and observed. RESULTS AND CONCLUSION: Significant differences in the spinal canal area improvement value and internal fixation failure rate were detected between the two groups (P < 0.05), and the observation group was better than the control group. The height ratio of anterior border of the vertebral body was higher at 12 months after treatment than that pretreatment, but Cobb angle was lower than pretreatment (P < 0.05). These data indicate that compared with cross-segment pedicle screw fixation, vertebral pedicle screw short-segment fixation for thoracolumbar vertebral fracture and dislocation obtains more ideal outcomes and higher safety. It is more in line with biomechanics at the same time ensuring the fixing strength.