OBJECTIVE:To evaluate the status quo and the developmental trend of the application of antidepressant drugs in our hospital.METHODS:The antidepressant drugs in our hospital during2002～2004were analyzed retrospectively in terms of drug varieties,consumption quantity,consumption sum,DDDs etc.RESULTS:The consumption sum of the antidepressant drugs increased year by year,which stood at667.41,802.47and995.02(RMB:ten thousand yuan),respectively in the3years.CONCLUSION:Fluoxetine dominates the first place in terms of clinical application of antidepressants.Furthermore,the application of new type antidepresants has been on the rise.

Child, Preschool ; Fibroma ; pathology ; Humans ; Male ; Oropharyngeal Neoplasms ; pathology

Objective To investigate the effects of bilateral sternocleidomastoideus contraction on neck flexion and extension. Methods The electromyograms (EMG) signals of left sternocleidomastoideus of 24 healthy persons were recorded respectively when neck relaxation and flexion in the supine position, and neck relaxation and extension in the prone position. The biomechanical measurement and analysis were done using anatomical specimens and models. Results The sternocleidomastoideus registered electrical resting potential when neck relaxation in the supine position, and when neck relaxation and extension in the prone position; the motor unit action potential of sternocleidomastoideus raised the type of mixed phase when neck flexion in the supine position. Conclusion The contractions of bilateral sternocleidomastoideus can lead to the head and neck flexion while neck joints are not fixed, and the contractions of bilateral sternocleidomastoideus can lead to the head extension under the state of fixing neck joints below atlanto-occipital.

Objective To investigate and analysis the situation of malocclusion of 49 skulls of ancient resident in Xinjiang, and discuss the history evolution and the pathologic mechanism of malocclusion. Methods The investigation was carried out based on the standard of individual normal occlusion. Results Among the group of 49 skulls, the morbility rate of malocclusion was 30. 61% ; in Angle's classification of malocclution, class I was the most (73. 33%); in Mao's classification of malocclution, class I was also the most (33. 33%). Conclusion The morbility rate of malocclusion of resident in bronze age is lower than that of modern resident and nearer ages resident. There is a close releationship between the human food construction and the pathogenesis of malocclution.

Objective To analyse the causes of medical complaints ,seek methods to prevent medical disputes .Methods All medical complaints were collected and analyzed retrospectively in 2011 .Results In 278 medical complaints ,there were 161 (57 .91% ) complaints by telephone ,101 (36 .33% ) complaints by hospital electronic touch screen ,16 (5 .76% ) complaints by E-mail;the top three complaint departments were vasculocardiology department 33(11 .87% ) ,department of gynaecology and obstet-rics 29(10 .43% ) ,urology department 26(9 .35% ) ,respectively ;the top three complaint reason were poor doctor-patient communi-cation 101(36 .33% ) ,poor service level 69(24 .82% ) and ward disadvantaged 45(16 .19% ) ,respectively .Conclusion Prevention of medical complaints of the most important measures is to improve the skill of doctor-patient communication and technical level of medical staff .Furthermore ,hospital should strengthen the construction of infrastructure .

A new fluorimetric method was developed for the determi nation of ethanol in alcoholic beverage. The method is based on the principle that tetrasubstituted sulphonated aluminum phthalocyanine (AlS4Pc), a red-r egion fluorescent reagent, is induced to associate in the presence of cationic s urfactant, cetyltrimethylammonium bromide (CTMAB), thus its fluorescence is quen ched, and then the aggregate is disaggregated by the a ddition of ethanol and the fluorescence is recovered. This method has a linear determination range of 0.5%～90.0%(V/V), the detection limit is 0.48%(V /V). The method has been used to determine real alcoholic beverage samples w ith satisfactory results.

The quantity and quality of the papers cited by SCI are key standards that measure the level of basic research,academic status and teaching quality of a university.In this paper,we studied on the papers cited by SCI by statistical analysis and comparative methods in 30 well-known Chinese and foreign medical universities from 2001 to 2005.The research result showed that there is some disparity in the scale and condition of the scientific research and the technical level among Chinese medical universities and foreign medical universities.Meanwhile,it Was suggested that how to improve the quantity and quality of the papers cited by SCI in Chinese medical universities.

OBJECTIVE To explore the risk factors and preventive measures of nosocomial infection among the diabetes mellitus patients with cerebrovascular accident.METHODS A retrospective survey on 574 diabetes mellitus patients with cerebrovascular accident was conducted.RESULTS The result showed that 126 of the 574 patients had nosocomial infection,the rate of infection was 22%.The risk factors of nosocomial infection included: age,hospitalized days,invasive treatment procedures and operation,application of antibiotics,course of diabetes mellitus,fasting plasma glucose(FPG),glycosylated hemoglobinA1C(HbA1C),clinical type of cerebrovascular accident,consciousness and bulbar palsy. The main infection sites were at lungs,urinary tract and intestines.The chief pathogens were Gram-negative bacteria.CONCLUSIONS Nosocomial infection is a high frequent complication in diabetes mellitus with cerebrovascular accident.Preventing and controlling the risk factors can reduce the rate of nosocomial infection among the diabetes mellitus patients with cerebrovascular accident.

Objective:To observe the effects of soybean isoflavones(SI) on uteri and uterine Er?,ER? expression in perimenopausal rats. Method:Female SD rats in age of 7-month-old were used as control and 11-month-old SD rats were divided into 5 groups,model group,diethylstilbestrol group and 3 test groups exposed to three doses of SI(ig:30,12,4.6 mg/kg?d) respectively for 35 d. Serum concentrations of estradiol(E2) ,testosterone(T) ,follicle-stimulating hormone(FSH) and luteinizing hormone(LH) were determined. Ultrastructure of uterine luminal surface was observed by scanning electron microscopy and hematoxylin-eosin staining. Expression of ER? and ER? in the uteri were determined by immunohistochemistry. Results:Low dose SI significantly increased serum E2(P

Objective:To treat the burned wounds with Kangmeifu burns ointment and observe the expression levels of EGF,TNF-? and TGF-?1 in the process of wound healing.Methods:Immunohistochemistry and image analysis methods were conducted to examine the expressions of EGF,TNF-? and TGF-?1 in both groups at 3,5,7,9 and 14 days after scalding.Results:①Expression of EGF:EGF began to express from the 1stday.It expressed significantly at the 5th day,maintained a higher level at the 7th and 14th days.In the blank control side,the peak expression occurred at the 7th day.② Expression of TNF-?:TNF-? had two peaks respectively in both sides.The peaks in the blank control side ocurred at the 3th and 9th days respectively,and the peaks in the Kangmeifu burns ointment treated side ocurred at the 3th and 7th days,and the second peak was obviously earlier than that in the blank control side.③Expression of TGF-?1 :TGF-?1 began to express from the 1stday.It expressed significantly at the 5th day,and reduced at the 9th day.In the blank control side,the peak expression occurred at the 7th day.In the blank control side,there was almost no TGF-?1 expression at the lst day.It expressed weakly at the 3th day.The peak expression occurred at the 7th day.Conclusion:Kangmeifu burns ointment can accelerate the process of wound tissue healing through enhancing EGF,TGF-?1 expression at the beginning and inhibiting TNF-? overexpression later.