Composite hemangioendothelioma (CHE) is a recently described vascular tumor of low-grade malignancy. We report a case of CHE in an 18-year-old woman who presented with a 2-month history of an enlarging palpable mass in the left axilla. Grossly, the excised tumor was relatively circumscribed, nodular, firm, and soft. It measured 6.0 x 4.5 x 4.0 cm. The cut surface revealed a whitish gray solid area and a dark red to tan cystic area containing necrotic material. Histologically, the tumor demonstrated variably intermixed benign and malignant vascular components. The benign components showed features of an arteriovenous malformation, capillary hemangioma, spindle cell hemangioma and cavernous hemangioma. The malignant components were composed of areas resembling retiform hemangioendothelioma, epithelioid hemangioendothelioma, Kaposiform hemangioendothelioma, and angiosarcoma. The angiosarcoma component showed a mixed epithelioid and spindle shaped cell morphology with moderate differentiation. A nearly imperceptible transition between the benign and malignant components was noted.
Adolescent ; Arteriovenous Malformations ; Axilla ; Female ; Hemangioendothelioma* ; Hemangioendothelioma, Epithelioid ; Hemangioma ; Hemangioma, Capillary ; Hemangioma, Cavernous ; Hemangiosarcoma ; Humans ; Triacetoneamine-N-Oxyl

Hepatic epithelioid hemangioendothelioma is a rare tumor of vascular origin having a intermediate clinical course between benign cavernous hemangioma and malignant anglosarcoma. Patients present nonspecific clinical signs and symptomas. We experienced a case of surgically proven hepatic epithelioid hemangioen-dothelioma. Computed tomography showed multiple nodules with internal calcifications, chiefly in peripheral portion of both lobes of the liver. Ultrasonography showed hypoechoic nodules and tiny calcific foci in peripheral portion. Open biopsy of the liver and the omenrum confirmed epithelioid hemangioendotheliomas.
Biopsy ; Hemangioendothelioma, Epithelioid* ; Hemangioma, Cavernous ; Humans ; Liver* ; Ultrasonography

Cavernous hemangioma is about one-tenth as common as capillary hemangioma, although congenital, is often not apparent at birth and may undergo a rapid growth phase during the 6 months of life. It arises from skin layers to muscles, bones or central nervous system. Cavernous hemangioma is much less likely to undergo spontaneous involution and tends to have a more aggressive course, and may result in complications related to its location. The authors experienced a case of atypical cavernous hemangioma which arose from the left parotid gland at adult onset, its size was wax and wane without any symptoms or complications and its shape was characteristically dumbbell-like, so report this case with a review of literatures.
Adult ; Central Nervous System ; Hemangioma, Capillary ; Hemangioma, Cavernous* ; Humans ; Muscles ; Parotid Gland* ; Parturition ; Skin

PURPOSE: To analyse the MR imaging characteristics of the soft tissue hemagiomas of the extremity. MATERIALS AND METHODS: We retrospectively reviewed histopathologically proven 18 cases of hemangiomas of the extremity including 15 cavernous hemangiomas, 2 venous hemangiomas and 1 capillary hemangioma. The lesions were frequent in female and low extremity. We analyzed the site, extent, margin, signal intensity, enhancement pattern, the homogeniety of internal architecture, and abnormal vessels near the lesion. RESULTS: The extensive lesions involving multiple muscle and tissue layers were more frequent than localized lesions (12/18). Twelve cases had ill defined margin. In most cases, the lesion was heterogeneous mass composed of nodular and septal components. The nodular component showed intermediate signal intensity in T1WI and hign signal intensity in T2WI. The setal component showed mixed inconstant signal intensity. One case of capillary hemangioma showed relatively homogeneous signal intensity than cavernous hemangioma and the main portion of 2 venous hemangiomas had mutilple tubular signal voids. At least some portion of the lesion was enhanced in all enhanced cases. CONCLUSION: The soft tissue hemangiomas of the extremity showed characteristic MR findings and MRI would be an useful method in the diagnosis of the soft tissue hemangiomas of the extremity.
Diagnosis ; Extremities* ; Female ; Hemangioma* ; Hemangioma, Capillary ; Hemangioma, Cavernous ; Humans ; Magnetic Resonance Imaging* ; Retrospective Studies

PURPOSE: To analyse the MR imaging characteristics of the soft tissue hemagiomas of the extremity. MATERIALS AND METHODS: We retrospectively reviewed histopathologically proven 18 cases of hemangiomas of the extremity including 15 cavernous hemangiomas, 2 venous hemangiomas and 1 capillary hemangioma. The lesions were frequent in female and low extremity. We analyzed the site, extent, margin, signal intensity, enhancement pattern, the homogeniety of internal architecture, and abnormal vessels near the lesion. RESULTS: The extensive lesions involving multiple muscle and tissue layers were more frequent than localized lesions (12/18). Twelve cases had ill defined margin. In most cases, the lesion was heterogeneous mass composed of nodular and septal components. The nodular component showed intermediate signal intensity in T1WI and hign signal intensity in T2WI. The setal component showed mixed inconstant signal intensity. One case of capillary hemangioma showed relatively homogeneous signal intensity than cavernous hemangioma and the main portion of 2 venous hemangiomas had mutilple tubular signal voids. At least some portion of the lesion was enhanced in all enhanced cases. CONCLUSION: The soft tissue hemangiomas of the extremity showed characteristic MR findings and MRI would be an useful method in the diagnosis of the soft tissue hemangiomas of the extremity.
Diagnosis ; Extremities* ; Female ; Hemangioma* ; Hemangioma, Capillary ; Hemangioma, Cavernous ; Humans ; Magnetic Resonance Imaging* ; Retrospective Studies

PURPOSE: To characterize the MR findings for a differential diagnosis and to make a plan for treatment by interventional technique of the vascular masses with/without hypertrophic feeding vessels of the head and neck. SUBJCETS AND METHODS: Seven patients with vascular masses of the head and neck proved by pathology, angiography, clinical findings were included. Vascular masses included 4 venous malformations, a capillary hemangioma, and a hemangiopericytoma, a hemangioma combined with arteriovenous malformation. 7 patients had MR studies with 1.0T and 1.5T using routine TI-, T2- weighted spin echo sequences, and contrast enhancement. 4 MR angiography, 3 inversion recovery, and 6 contrast angiography were studied from 7 patients RESULTS: All vascular masses demonstrated higher than muscle signal intensity on Tl-weighted images, bright signal intensity on T2-weighted images, and prominent enhancement, except AV hemangioma combined with prominent arteriovenous malformation on postcontrast scan. Three hemangiomas demonstrated distinct serpiginous signal voids. Venous malformations demonstrated venous lakes seen as homogenous regions of high signal intensity and phleboliths seen as low signal foci on images. Inversion recovery was the best pulse sequence for evaluation of the extent of lesion. CONCLUSION: MR findings of the vascular masses of the head and neck are useful in delineating the extent of the disease, differentiating venous malformation or cavernous hemangioma from other hemangiomatous lesions including hypertrophic feeding vessels, and making a plan for treatment by interventional technique also.
Angiography ; Arteriovenous Malformations ; Diagnosis, Differential* ; Head* ; Hemangioma ; Hemangioma, Capillary ; Hemangioma, Cavernous ; Hemangiopericytoma ; Humans ; Lakes ; Neck* ; Pathology

HUMANS FEMALE CHILD NEOPLASMS NEOPLASMS BY HISTOLOGIC TYPE NEOPLASMS ; VASCULAR TISSUE HEMANGIOMA CENTRAL NERVOUS SYSTEM VENOUS ANGIOMA HEMANGIOENDOTHELIOMA HEMANGIOMA ; CAPILLARY RESPIRATORY SYSTEM LARYNX

Hemangioams are usually present at birth of appeat shortly thercafter, as red or purple patches varying in size and most often in the skin. Hemangiomas include the cervix in their ubiquitous distribution; the cervix itself is very vascular and many reported hemangiomas are nothing more than a conspicuous demonstration of local casculatity. The cervical hemangioma is a rare condition which usually presents as vaginal bleeding of unusual cause, Many of the capillary hemangiomas and some of the cavermous types frequently resolve spontaneously. However, some hemagiomas ulcerate and a severe hemorrhage results. We recently encountered a case of cervical hemangioma involving the vagina in a 56-year-old woman. This case os especially interesting in that the histologic type was a cavernous hemangioma with uncommon cariety n the uterine cervix.
Cervix Uteri* ; Female ; Hemangioma ; Hemangioma, Capillary ; Hemangioma, Cavernous* ; Hemorrhage ; Humans ; Middle Aged ; Parturition ; Skin ; Ulcer ; Uterine Hemorrhage ; Vagina*

Hemangioams are usually present at birth of appeat shortly thercafter, as red or purple patches varying in size and most often in the skin. Hemangiomas include the cervix in their ubiquitous distribution; the cervix itself is very vascular and many reported hemangiomas are nothing more than a conspicuous demonstration of local casculatity. The cervical hemangioma is a rare condition which usually presents as vaginal bleeding of unusual cause, Many of the capillary hemangiomas and some of the cavermous types frequently resolve spontaneously. However, some hemagiomas ulcerate and a severe hemorrhage results. We recently encountered a case of cervical hemangioma involving the vagina in a 56-year-old woman. This case os especially interesting in that the histologic type was a cavernous hemangioma with uncommon cariety n the uterine cervix.
Cervix Uteri* ; Female ; Hemangioma ; Hemangioma, Capillary ; Hemangioma, Cavernous* ; Hemorrhage ; Humans ; Middle Aged ; Parturition ; Skin ; Ulcer ; Uterine Hemorrhage ; Vagina*

We herein describe two cases of sudoriparous angioma consisting of increased number of eccrine sweat glands associated with angiomatous vascular channels. Case 1 is a 16 year-old girl developing two, painful and tender cavernous hemangiomas which sweated whenever compressed. These were located on her left gluteal area since early childhood. The biopsy specimen revealed an increased number of cystically dilated eccrine glands in the mid-dermis in addition to vascular components in the lower dermis. Case 2 is a five year-old girl manifesting non-tender, slightly hyperhidrotic nevus flammeus-like eruption on her left suprapopliteal area since birth, the biapsy apecimen of which revealed an increased number of eccrine glands admixed with capillary hemangioma in the mid-dermis.
Adolescent ; Biopsy ; Dermis ; Eccrine Glands ; Female ; Hemangioma* ; Hemangioma, Capillary ; Hemangioma, Cavernous ; Humans ; Nevus ; Parturition ; Sweat ; Sweat Glands