1.Latest development of medical monitors technology in China
Chinese Medical Equipment Journal 2004;0(08):-
As an important device of modern medical treatment,medical monitor is a combination of modern electronics technology,computer technology and medical technology.In this paper,the development of medical monitors in China is summarized,especially the main technique characteristics of medical monitor in Chinese market.The examples of monitors made in China are presented.
2.Performance verification of three ischemia-modified albumin reagents
Qian HE ; Ruihua YANG ; Qi WANG
International Journal of Laboratory Medicine 2016;37(5):606-607,610
Objective To verify the performance of three kinds of ischemia‐modified albumin(IMA) reagents .Methods The performance of three IMA reagents(labeled as reagent A ,B ,C) using colorimetric method from Shanghai Aikang Biotechnology Co .,Ltd .,Zhejiang Kuake Bioscience Technology Co .ltd .and Beijing Jiuqiang Biotechnology Co .,Ltd .were assessed by using O‐lympus AU5800 automatic biochemistry analyzer .According to the National Committee for Clinical Laboratory(NCCLS) EP6‐A , EP15‐A and EP7‐A documents and WS/T 420‐2013 verificationof analytical performance of quantitative kits by clinical labo‐ratory ,the precision ,linearity range ,accuracy and anti‐interference capability were assessed .Results The within‐run coefficient of variations(CVs) of reagent A ,B and C were 0 .59% -0 .82% ,0 .27% -0 .54% and 0 .62% -0 .69% respectively .The between‐run CVs of reagent A ,B and C were 0 .98% -1 .74% ,0 .99% -1 .01% and 0 .71% -0 .78% ,respectively ,which were lower than decla‐rations of these reagent kits .The linearity range of reagent A ,B and C were 11 -142 U/mL(r2 = 0 .993) ,10 -120 U/mL(r2 =0 .996) ,14-123 U/mL(r2 =0 .992) respectively ,which showed good linearities .About interference tests ,no remarkable interfer‐ences(all Bias were less than ± 10% ) of reagent A ,B and C were detected when Vitamin C≤10 mg/dL ,hemoglobin≤200 mg/dL , bilirubin≤40 mg/dL and triglyceride≤500 mg/dL .Conclusion The three IMA reagents show high precision ,which could meet clinical requirements ,nevertheless ,differences of anti‐interference capabilities are observed in these three reagents .
3.Surgical management of the complications after endoscopic sphincterotomy
Guanhai HE ; Yang CAI ; Xiyuan QIAN
Chinese Journal of General Surgery 2001;0(08):-
ObjectiveTo review surgical management of the complications caused by iatrogenic endoscopic sphincterotomy(EST).MethodsEleven patients with complications of EST were surgically treated, including 4 patients with hemorrhage, 3 patients with perforation, 3 patients with perforation plus hemorrhage, and one patient with perforation plus severe pancreatitis. ResultsTwo patients with perforation plus hemorrhage and the patient with perforation plus severe pancreatitis died, other patients survived.ConclusionEarly diagnosis and surgical intervention was very important to lower the mortality. For patients suffering from perforation and hemorrhage or pancreatitis, it′s very important to make an unobstructed peritoneal drainage as well as other maneuvers.
4.Performance Verification of LP(a)Reagents in Clinical Laboratory
Qian HE ; Ruihua YANG ; Qi WANG
Journal of Modern Laboratory Medicine 2016;(1):125-127
Objective To validate the analytical performance of four LP(a)reagents with Immunoturbidimetry method used on the automatic biochemistry analyzer for preliminary clinical application.Methods The performance of four LP(a)reagents (labeled as A,B,C,D)with method from RANDOX,Zhejiang Kuake Co.,Beijing Leadman Co.and Beijing Jiuqiang Co.on Olympus AU5800 automatic biochemistry analyzer were assessed.The precision,linearity range,accuracy,disturbance (vita-min C,bilirubin,hemoglobin,TG)were assessed.Results The within-run CVs of the four reagents (A,B,C and D)were 0.64%~1.18%,3.59%~4.75%,1.33%~3.05% and 1.43%~2.01% respectively.The between-run CVs in A,B,C and D were 1.04%~1.7%,3.81%~4.93%,2.16%~4.76% and 2.33%~3.21% respectively,lower than the stated.The lin-earity range was 82~923 mg/L (r2 =0.997),130~935 mg/L (r 2 =0.996 4),120~1025 mg/L (r 2 =0.992 1)and 117~943 mg/L (r2 =0.999 5)in the four reagents,which demonstrated a sound linear correlation.For interference tests,no re-markable interferences (<±10%)of reagent A and reagent D were detected when Vitamin C≤10 mg/dl,hemoglobin≤200 mg/dl,bilirubin≤40 mg/dl and TG≤500 mg/dl.Interference of reagent B was found when VC≥5 mg/dl,TG≥250 mg/dl and when TG≥250 mg/dl reagent C was interfered significantly.The four LP(a)reagents were used to detect the lipid con-trol,and the deviations of the target value were - 8.07%,1.34%,- 8.05% and 7.38% respectively.Conclusion When used in automatic biochemical analyzer,the four LP(a)reagents showed high precision.The four reagents are all able to meet clinical test requirements,nevertheless,anti-interference capability were different.
5.Effects of inducers of differentiation on telomerase activity in malignant cells
Liming ZHANG ; Qian HE ; Guang YANG ; Zhilong CHEN
Chinese Pharmacological Bulletin 2001;17(2):140-142
More than 85% of all cancers express telomeras e activity. Human telome rase has been proposed as a novel and potentially highly selective target for ca ncer therapy. Inducers of differentiation are involved in regulation of telomera se activity. In the present review, the effects of retinoids, vitamin D3 compo unds, tea catechins and matrine on telomerase activity in malignant cells were r eviewed.
6.Effects of aerobic exercise on quality of life in patients with rheumatoid arthritis
Chengsong HE ; Fangyuan XU ; Qian YU ; Dajian YANG ;
Chinese Journal of Physical Medicine and Rehabilitation 2003;0(09):-
Objective To assess the quality of life(QOL) in rheumatoid arthritis(RA) patients treated with 12weeks of aerobic exercise(AE) plus medication(methotrexate, MTX, and NSAIDs). Methods The research design was a randomized controlled trial. The patients in AE group received AE plus MTX and NSAIDs, and the patients in the control group received drug therapy only. Results One hundred and twenty six patients completed the trial, AE patients with improvement of 12%~28% from the baseline were better than medicine treated patients in the physical, social, emotional function, self recognized health status and total QOL. Conclusion AE is effective for the patients with RA in the improvement of QOL.
7.Identification of the Specific Proteins in Two Hydrophis with a Simple Differential Proteins Display Method
Honhui ZENG ; Yanjun YANG ; Yajun HE ; Qian WU
Traditional Chinese Drug Research & Clinical Pharmacology 1993;0(02):-
Objective To identify the specific proteins in two hydrophis (l#and 2#) with a simple differential proteins display method. Method By means of SDS-PAGE and Western blot, combined with analysis, the specific proteins in two hydrophis were obtained and been sequencing.Result The specific proteins of l#are 14.6kD and 8.7kD components and of 2#are 16.7kD. 10.2 kD components. The amino acid sequences of 14.6 kD and 10.2 kD components were assayed respectively. Conclusion Differential proteins can be obtained and used to identify the Chinese traditional medicinal crops by means of one-dimensional electrophoresis combined with antigen analysis .
8.Effects of inducers of differentiation on telomerase activity in malignant cells
Liming ZHANG ; Qian HE ; Guang YANG ; Zhilong CHEN
Chinese Pharmacological Bulletin 1987;0(02):-
More than 85% of all cancers express telomerase activity. Human telomerase has been proposed as a novel and potentially highly selective target for canon therapy. Inducers of differentiation are involved in regulation of telomerase activity. In the present review, the effects of retinoids, vitamin D3 compounds, tea catechins and matrine on telomerase activity in malignant cells were reviewed.
9.A new norditerpenoid alkaloid from Aconitum taipaicum
Yangqing HE ; Zhanying MA ; Qian YANG ; Binghua YAO ; Liming GAO
Acta Pharmaceutica Sinica 2008;43(9):934-937
To investigate the chemical constituents of the roots of Aconitum taipaicum, silica gel column chromatography was used for the isolation and purification of compounds. A new norditerpenoid alkaloid, isodelelatine (1), along with five known alkaloids, atisine (2), delfissinol (3), liangshanine(4), hypaconitine (5) and delelatine (6) were isolated and identified. The structure of the new compound was elucidated on the basis of spectral data.
10.Effects of ginsenoside Rg-1 on the expressions of interleukin-6,bone gla protein in periodontal tissues in periodontitis rats
Qian YANG ; Zhanhai YU ; Jiandong DU ; Guoying ZHANG ; Fude HE
Journal of Practical Stomatology 2001;0(01):-
Objective:To determine the effects of ginsenoside Rg1 on the expression levels of bone gla protein(BGP) and cytokine interleukin-6(IL-6) in the periodontium of experimental periodontitis rats.Methods:One hundred 160-200 g Wistar rats were randomly divied into ten groups.Group A used as control were killed at the beginning of the experiment.Group B-J were experimental periodontitis models.Group B-E received the therapy of ginsenoside Rg1 were killed at 1st,2nd,3rd and 4th weeks.Group F-J received no treatment as periodontitis control were killed at 0,1st,2nd,3rd and 4th weeks.The expression levels of BGP and IL-6 in the periodontium were measured by immunohistochemistry.Results:The expression levels of BGP in the group F were significantly lower than that in the group A,the expression levels of IL-6 in the group F were much higher than that in the group A(P