1.Common causes of headache and the treatment
Chinese Journal of Practical Internal Medicine 2001;0(06):-
Headache is a common clinical symptom.Some headache disorders belong to secondary category.Many intracranial disorders,such as head trauma,cerebral vascular diseases,intracranial tumors and inflammation,can lead to headache due to mass effect,inflammation reaction,stimulation of vasoactive substances and decreased intracranial pressure.Furthermore,many drugs and other substances,disorders of eyes,nose,ear,mouth,neck and other systemic disorders can also cause headache.Many headache disorders can be determined by detailed case history and physical examination.Blood test,lumber puncture,CT,MRI and other imaging examinations are necessary methods for finding the causes and the treatment of diseases.
2.Adverse events related to bevacizumab and the management principles in non-small cell lung cancer.
Chinese Journal of Lung Cancer 2010;13(6):563-567
Angiogenesis Inhibitors
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adverse effects
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Antibodies, Monoclonal
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adverse effects
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Antibodies, Monoclonal, Humanized
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Bevacizumab
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Carcinoma, Non-Small-Cell Lung
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drug therapy
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Hemorrhage
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chemically induced
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Humans
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Hypertension
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chemically induced
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Lung Neoplasms
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drug therapy
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Proteinuria
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chemically induced
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Thromboembolism
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chemically induced
3.Study on sandtray topic features for children with behavior problems based on the grounded theory method
Hua CHENG ; Xiaolei ZHANG ; Gang HUANG
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(12):1070-1072
Objective To analyze the sandtray topics of the children with behavior problems according to the grounded theory method.Methods Collected and described children' s sandtray topics of different types of behavior problems,age and gender.And analyzed them base on a 3 levels coding list compiling according to the ground theory method.Results The frequency of “negative theme” (3.33 ± 1.25 ) was higher than “positive theme” (0.81 ± 1.25 ) with significant difference (P<0.01) in feature level 1.Age factor had significant effect upon the frequency of “positive theme” in feature level 1 (P < 0.05 ).And also had impact on “harmony”,“ development” in features level 2 (F =3.039,P < 0.05 ).Gender factor,interaction of gender and age had significant effects on frequency of “negative theme” in feature level 1 (F =5.395,P < 0.05 ; F =4.222,P < 0.05 ).Conclusion The characteristics of the children' s sandtay with behavioral problems mainly are “negative theme”.And it shows different features in children with different gender or age.
4.Questions and Countermeasures of Clinical Teaching for Medical Undergraduates
Guanghe WEI ; Gang CHENG ; Jinguo ZHANG
Chinese Journal of Medical Education Research 2003;0(04):-
Objective:To investigate the problems and improve the quality of clinical education.Method:A questionnaire was made among 200 medical students at Ji'ning medical college.Results:About eighty-eight percent of the students were satisfied with their clinical education,but there were still some problems:absence of clear objectives in clinical practice;shortage of enthusiasm of the students;lack of responsibility of some teachers and too many factors affecting clinical practice.Conclusion:The key points to improve clinical education quality are to set up clear education objectives,develop appropriate clinical practice methods,improve teaching staff quality and reform the teaching content.
5.Neuroprotective effect of bFGF on cerebral diffuse axonal injuries of rats
Hongqi LI ; Yuzhi ZHANG ; Rongfeng GAO ; Zhanbo ZHANG ; Gang CHENG
Chinese Journal of Rehabilitation Theory and Practice 2003;9(7):414-415
ObjectiveTo observe the neuroprotective effect of basic fibroblast growth factor(bFGF)on cerebral diffuse axonal injuries (DAI)of rats.Methods40 male SD rats were randomly divided into control group, DAI injury group, bFGF group and DAI saline group. According to the survival time of rats, DAI injury group were divided into five groups, the 6h, 12h, 24h, 72h and 7th day group, The changes of bFGF expression in cerebral cortex were detected by immunohistochemical method from 6h to 7d after DAI. Two hours before DAI, bFGF 10μl was injected into right ventricle in bFGF group. ResultsThe bFGF expression appeared at 6h after DAI, increased at 12h, reached the highest level at 72h, and kept in a high level at 7d.There were obvious differences between 72h group and other groups in DAI injury group (P<0.01),cerebral cortex neurons were obviously decreased by HE staining. In each time group,injured neurons were decreased in bFGF group combined with DAI injury group(P<0.05). ConclusionsbFGF has obvious neuroprotective effect on cerebral diffuse axonal injuries of rats.
6.Comparative analysis of video-assisted thoracoscopic surgery with conventional surgery for patients with thymoma clinical effect
Chinese Journal of Biochemical Pharmaceutics 2017;37(10):435-437
Objective To compare the clinical effect of video-assisted thoracoscopic surgery and traditional surgery on patients with thymoma. Methods 52 patients with thymoma were randomly divided intoexperimental group and control group each with 26 cases. The control group received the traditional surgical method. The experimental group was treated by video-assisted thoracoscopic surgery. To compare the two groups of patients with intraoperative blood loss, surgical incision, operation time, analgesic drug use, hospital stay and complications and other indicators. Results The intraoperative blood loss, incision size and the amount of analgesic drug application of the experimental group were significantly smaller than those of the control group(P<0.05). The operation time and hospitalization time were significantly shorter than those of the control group. The complication was significantly lower than the control group, the difference was statistically significant(P<0.05). Conclusion Video - assisted thoracoscopic surgery is safe and reliable in the treatment of thymoma. It has the characteristics of less trauma, quick recovery, less pain and less complication. It should be widely used in clinical practice.
7.Expression of TIMP-2 in peripheral blood lymphocytes in patients with chronic obstructive pulmonary diseases
zhen-ping, HU ; yi-cheng, ZHANG ; jun-gang, XIE
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(04):-
Objective To explore the expression of tissue inhibitor of metalloproteinases-2(TIMP-2) in peripheral blood lymphocytes in patients with chronic obstructive pulmonary diseases(COPD) and the association of smoking and TIMP-2 mRNA. Methods The expression of TIMP-2 mRNA in peripheral blood lymphocytes was measured by reverse transcription-polymerase chain reaction(RT-PCR) in 44 patients with COPD and 42 healthy smokers.The correlation analysis was then conducted between TIMP-2 mRNA expression and smoking index. Results The expression of TIMP-2 mRNA was 0.753?0.154 and 1.170?0.196,respectively,in patients with COPD and healthy smokers(P
8.Quality of sleep in middle school teachers.
Gang CHENG ; Xiao-qing ZHANG ; Mian-zhen WANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2009;27(12):757-759
Adult
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Faculty
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Female
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Humans
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Male
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Middle Aged
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Sampling Studies
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Sleep
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Surveys and Questionnaires
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Young Adult
9.Influence of lidocaine on systemic inflammation in perioperative patients undergoing cardiopulmonary bypass
Chuanbin SUN ; Libo CHEN ; Ying CHENG ; Gang FEANG ; Weixing ZHANG
Journal of Peking University(Health Sciences) 2003;0(06):-
Objective: To investigate the influence of lidocaine on systemic inflammation in the perioperative ventricular septal defect (VSD). Methods: Twenty patients, scheduled for ventricular septal defect were randomly divided into 2 groups: lidocaine and control groups. Before rebeat lidocaine 1 mg/kg was given.The venous blood samples were obtained from the central venous at the following points: after induction of anesthesia and before cardiopulmonary bypass(CPB,T1),1 h after CPB(T2),2 h after CPB(T3), and 4 h after CPB(T4). IL-6 and IL-8 were determined by radio-immunoassay. Results: Compared with those at T1, the levels of white blood cells,polymorphonuclear neutrophils,IL-6 and IL-8 increased significantly from T2 to T4 in both groups. IL-6 and IL-8 levels reached the peak at T2. Compared with those in control groups, IL-6 level decreased obviously in lidocaine group from T2 to T4, but IL-8 level remained unchanged significantly. Conclusion: Under CPB and VSD repair the systemic inflammation is obvious, reaches the peak 30 min after CPB and persists to 4 h after CPB. Perioperative administration of lidocaine is effective against the inflammation.
10.Continuous infusion of propofol combined with midazolam for patients undergoing long-time microsurgeries
Gaofeng ZHANG ; Gang LI ; Yongguang XU ; Xianling CHENG
Basic & Clinical Medicine 2006;0(07):-
Objective To investigate the sedative effect of propofol combined with different doses of midazolam in patients undergoing long-time microsurgeries.Methods Forty ASA(American Society of Anesthesiologists)Ⅰ~Ⅱ patients were randomly divided into 4 groups.Normal saline(NS) 2 mL was administered in groupⅠ,while midazolam 0.01,0.02 and 0.04 mg/kg was administered in groupⅡ,Ⅲ,Ⅳ respectively.one min later,propofol was infused at a rate of 5~10 mg/kg?h combined with midazolam based on the abovementioned dosage per hour for groupⅡ,Ⅲ,Ⅳ respectively.Taking auditory evoked potential index(AAI) as a parameter,after it decreased to 40,the infusion rate of propofol was adjusted to keep AAI at the level of 30~45,and maintained the level by infusing propofol and midazolam for 5 hours.The dosage of propofol required for induction and maintenance was recorded.The emergence time and whether patients had awareness during the operation were recorded after the infusion stopped.Results At the target sedative level of AAI 30~45,the Observer's Assessment of alertness/sedation(OAA/S) score of all patients in the four groups reached 0~1.The induction period was obviously shortened and the propofol dosage was dramatically reduced in group Ⅱ~Ⅳ as compared with groupⅠ.At the stage of maintenance of sedation,the dosages of propofol in both groupⅠandⅡ were larger than those in group Ⅲ and Ⅳ.The emergence time in group Ⅳ was dramatically longer than the other groups(P