Nishimura in 1943 indicated for the first time that a serious endemic focus of Clonorchis sinensis is located in the vicinity of Yeong-cheon(Kyungpook Province, Korea). Later, numerous surveys of this fluke in the Province have been made, but no additional report on the endemic focus of the fluke has been available. The overall percentage of Clonorchis sinensis infections, based on the discovery of eggs by the formalin-ether sedimentation technique, was found to be 54.8 percent from 851 residents in Nakjeon ri (village), Danmil myun, Uiseong gun (county), Kyungpook Province and no significant difference was observed in the sex specific rate of the individuals infected. There is a high incidence of infection with Clonorchis sinensis. The infection rate in the age group from 0 to 4 years was 14.6 per cent, 5 to 9 years was 35.7 per cent and 10 to 14 years was 51.7 per cent. In the worn burdens for residents, the average number of egg-counts was 41,800. It is found that a serious endemic focus of Clonorchis sinensis exists in the vicinity of Nakjeon village.
parasitology-helminth-trematoda-Clonorchis sinensis ; epidemiology ; formalin-ether

Formalin is a 37 5pg aqueous solution of formaldehyde gas and formaldehyde may be present in products as an active ingredient, preservative or contaminant. This contamination may be from the container, the package material or in situ formation by degradation of the formaldehyde releasers. The free formaldehyde content was determined in the 50 kinds of Korean shampoos by quantitative analysis recently described, the lutidine method, which is simple, rapid and used for colored products which cannot be analysed by the chrornotropic acid method. Formaldehyde has been found in 46 out of the 0 samples, i.e., 90g., and the concentration ranged from 0. 1 to 78. 6 pg/ml(0. 1 78. 6 ppm).
Formaldehyde*

Combined technic of formalin-ether sedimentation and zinc sulfate flotation was carried out to compare the detection rate of Paragonimus eggs in feces between formalin-ether sedimentation technic and zinc sulfate centrifugal flotation, using the feces of cat infected with Paragonimus westermani for former and intestinal contents of rabbit infected with Metagonimus yokogawai for latter. And following results were obtained. Zinc sulfate method was highly excellent in detection of Paragonimus eggs in feces, on the contrary, formalin-ether technic was very poor, and the other hand, formalin-ether technic was highly excellent in detection of Metagonimus eggs, on the contrary, zinc sulfate method was extremely poor. The time which was needed in carrying out the combined technic was shorter than the cumulative time of each of the formalin-ether technic and zinc sulfate method was. Author emphasizes that the combined technic may be used in general parasitic examination of feces, so that excellent results would be obtained in detection of all kinds of helminthic ova and protozoa.
parasitology ; helminth ; trematoda ; Paragonimus westermani ; Metagonimus yokogawai ; diagnosis ; formalin ; ether ; zinc sulfate

The efficacy of the cellophane thick smear(CTS) technique was reassessed for detecting helminths eggs such as Ascaris lumbricoides, Trichuris trichiura and Clonorchis sinensis, in comparsion with the formalin-ether(F-E) one, with repeated smears per case. From the fecal samples of 411 ROK Army soldiers, a total of 3,288 smears were made and examined; 4 by CTS and 4 by F-E techniques. The expected egg detectability with one, two, three or four smears by each technique was mathemativally calculated. The results were as follows: When the results of all 8 smears per case were integrated, the number of cases eith Ascaris egg were 54(13.1%), Trichuris 125(30.4%) and Clonorchis 33(8.0%). Some other kinds of helminths eggs and protozoan cysts were found from a few cases each. The calculated detectability of Ascaris eggs by CTS technique was fairly high(95.8 - 96.3%) with 1-4 smears, while that by F-E technique was not so high(73.1 - 88.9%). In case of Trchuris eggs, the egg detectability by CTS technique with 1-4 smears was a little lower(62.2-86.4%) than that by F-E technique(73.4 - 91.2%). The detectability of Clonorchis eggs with 1-4 smears by CTS technique was the lowest(44.7 - 60.6%) among the three helminths as well as much lower than that by F-E technique(67.4 - 87.9%).
parasitology-helminth-trematoda-nemaoda ; Ascaris lumbricoides ; Trichuris trichiura ; Clonorchis sinensis ; diagnosis ; formalin ; ether

One fifth dilution of formocresol is usually used for pulpotomy of the primary teeth and emergency pulpotomy of the permanent teeth. However, the use of formaldehyde has been subjected to criticism because it may be absorbed into the blood stream and become distributed systemically, it may also alter the pulp tissue rendering it immunologically active, and have carcinogenic potential. Recently Depulpin(R)(VoCo., Germany) gains popularity as a devitalizing agent during root canal therapy in spite of high concentration of 49% paraformaldehyde because it facilitate devitalization of pulp and make root canal therapy easier. But there have been not enough publications about the reaction of pulp and periapical tissue caused by Depulpin. This study was performed to evaluate the histological changes in pulp and periapical tissue of rats after pulpotomy using formocresol and Depulpin and to elucidate the toxic effects of these agents. Thirty six Sprague-Dawley rats were anesthetized by intraperitoneal injection of ketamine. Maxillary first molar teeth were used for pulpotomy with formocresol and Depulpin. Rats were sacrificed after 2 days, 4 days, 1 week, 2 weeks, 3 weeks and 4 weeks respectively. Specimens were histologically observed by light microscope changes in pulp and periapical tissue. The obtained results were as follows. 1. Formocresol group A zone of fixed tissue, in which odontoblasts could clearly be defined, was present directly underneath the pulpotomy dressing in almost all teeth of this group. This was followed by an area of necrotic tissue which resembled dried out fibrous tissue with no cellular detail except some pyknotic nuclei. In the specimens of after 2 days, 4 days, 1 week, 2 weeks in which vital tissue was present, it was separated from the fibrous area by a zone of inflammation. In the specimens of after 3 weeks and after 4 weeks, inflammatory infiltrate was in the periodontal ligament adjacent to the apical foramina of the teeth. 2. Depulpin(R) group The area of necrotic tissue which had no cells and fibers, was present adjacent to the dressing. This was followed by dried out fibrous tissue with no cellular details except some pyknotic nuclei. A short stump of vital pulp with odontoblasts was present at the end of the canal after 2 days. Inflammatory infiltrate was in the periodontal ligament after 4 days and after 1week. Severe root resorption and necrosis of periapical tissue opposite the root resorption site were defined after 2 weeks and after 3 weeks. Periapical lesion which consist of necrotic tissue surrounded by a fibrous connective wall, was found after 4 weeks. The results indicated that Depulpin can cause more adverse reaction to the dental pulp and periapical tissue than formocresol, and further studies are needed for its clinical use with safety.
Animals ; Bandages ; Computer Communication Networks ; Dental Pulp ; Emergencies ; Formaldehyde ; Formocresols ; Inflammation ; Injections, Intraperitoneal ; Ketamine ; Light ; Molar ; Necrosis ; Odontoblasts ; Periapical Tissue ; Periodontal Ligament ; Polymers ; Pulpotomy ; Rats ; Rats, Sprague-Dawley ; Rivers ; Root Canal Therapy ; Root Resorption ; Tooth ; Tooth, Deciduous

Formaldehyde and its derivatives are used to improve the wet strength, waterresistance, shrink-resistance, grease-resistance and other characteristics of paper and. paper products. We have recently analyzed 78 different kinds of paper sources which are being used in Korea by the lutidine method. The forma.ldehyde concentrations of the most paper sources were under 50 ug/gm ranges except 4 copying paper sources which were in the 50 to 100 ug/gm ranges.
Formaldehyde* ; Korea

Formaldehyde in adhesives is used as preseratives as well as adhesives themeseles such as phenol-formaldehyde, carbamide-formaldehyde and melarnine-forma 1dehyde. Formaldehyde content in 43 kinds of adhesives used at present in Korea was determined by lutidine method. The study result was as follows. 1. The The distribution of formaldehyde concentrations of 43 different kinds of adhesives was in the 0 to 333. 9 ppm ranges. 2. High concentration of formaldehyde was observed in 3 kinds of wall paper adhesives and 1 kind of stationary adhesive, which has an important clinical significance because of their frequent contact sources of domestic uses.
Adhesives* ; Formaldehyde* ; Korea

Forensic Medicine ; Formaldehyde

For seven years from 1962 to 1968, fecal specimens of the patients were examined not only for the discovery of intestinal protozoa and helminths, but also to provie data on the incidence of intestinal parasites among the residents of Kyungpook Province, Korea. The Formalin-ether sedimentation, Lugol solution, and Heidenhain's iron-hematoxylin stained films were prepared for the recovery of intestinal parasites. Of 2,414 samples of feces examined, 35.7 percent were found to be infected with one or more species of protozoa. Among six species of protozoa detected, Entamoeba coli was observed most frequently(15.3%) followed by Entamoeba histolytica (11.9%), and then the Enteromonas hominis least often(1 case). For the survey of helminth, of a total of 5,288 fecal specimens examined, 86.7 percent were positive for one or more species of helminths. Trichocephalus trichiurus revealed the highest infection rate (83.6%), while Trichostrongylus orientalis was next (61.6%), and Ascaris lumbricoides was unexpectedly low(40.9%). The incidence for hookworm and Clonorchis sinensis was 22.4 percent and 29.8 percent respectively. Triple infections were found more frequently than double infections, and mixed infections of six or more species of helminths were observed in 3.8 percent of specimens.
parasitology-helminth-protozoa-nematoda-cestoda-trematoda ; Entamoeba coli ; Entamoeba histolytica ; Enteromonas hominis ; Endolimax nana ; Iodamoeba butschlii ; Giardia lamblia ; Trichocephalus trichiurus ; Trichostrongylus orientalis ; Ascaris lumbricoides ; hookworm ; Clonorchis sinensis ; Enterobius vermicularis ; Paragonimus westermani ; Metagonimus yokogawai ; Taenia species ; epidemiology ; stool examination ; Formalin-ether ; sedimentation ; Lugol solution ; Heidenhain's iron-hematoxylin

Quaternium-15 (Dowicil 200) which is a water-soluble antimicrobial agent and a formaldehyde releaser is widely being used as a preservative in cosmetics and medicaments these days. However, there are scanty reports about it in the Korean literature. Recently, we have experienced two cases of Quaternium-15 contact dermatitis probably related with their cosmetics and topical medicament, respectively. We report our cases with the patch test results.
Dermatitis, Contact* ; Formaldehyde ; Patch Tests