Objective To evaluate the clinical results of phacoemulsification combined with pars plana vitrectomy for eyes with cataract and proliferative diabetic retinopathy. Design Non-controlled retrospective case series study. Participants 123 eyes with proliferative diabetic retinopathy (PDR) and cataract. Methods Phacoemulsification,posterior chamber intraocular lens (PCIOL) implantation combined with pars plana vitrectomy were done in 123 eyes with proliferative diabetic retinopathy (PDR) and cataract. Postoperative vision,number of secondary procedures and surgical complications were analyzed. Main Outcome Measures Postoperative visual improvement and associated complications. Results All 123 eyes underwent combined surgery. The average follow-up was 10 months. 99 eyes (81%) experienced postoperative vision improvement of varying degrees. Vision improved by 2 lines or more in 93 eyes (76%). No apparent corneal edema or corneal decompensation were encountered. One patient with type 1 diabetes developed neovascular glaucoma 6 months after surgery. Retinal detachment occurred in 1 eye and reoperated. Vitreous hemorrhage requiring secondary procedure happened in 4 eyes. All 24 eyes (19%) without vision improvement were found to be with diabetic maculopathy. Conclusions Phacoemulsification combined with pars plana vitrectomy can be used as an effective surgical tool to improve visions in patients with PDR and cataract. Diabetic maculopathy is the major cause of poor visual improvement. (Ophthalmol CHN ,2006,15: 198-201)

Objective: To investigate the feasibility of performing endovascular recanalization therapy (ERT) in patients with acute basilar artery occlusion (BAO) of broadened time window (≥24 hours) based on clinical-diffusion mismatch (CDM). Methods: A total of 11 CDM patients whose Glasgow Coma Scale (GCS) score <8 at admission were recruited and the diffusion-weighted imaging (DWI) did not find their brainstem reticular formation and bilateral damage to hypothalamus. Intra-arterial thrombolysis (IAT) with rt-PA alone or in combination with IAT, percutaneous transluminal angioplasty (PTA) and stenting were used. At the same time, the degree of recanalization was evaluated according to the thrombolysis in myocardial infarction (TIMI) criteria and the complications were observed. The modified Rankin scale (mRS) was used to assess after 3 months. Results: Circled digit oneThe mean onset time and duration of coma of the 11 patients were 42 hours (range 25 to 73 hours) and 11 hours (range 2 to 24 hours), respectively. The mean GCS score at admission was 6 (range 3 to 7) and that was 14 (range 3 to 15) at discharge. Circled digit twoNine patients performed ERT successfully (n = 2, TIMI grade 2, n = 7, TIMI grade 3) and 2 failed (TIMI 0). There were no complications such as bleeding. The patients regained consciousness within 9 to 27 hours. Circled digit threeThe patients were followed up after 3 months, 7 had good outcome (mRS, 0 to 2) and 2 had poor outcome (mRS, 3). ERT failed in 2 patients and they died at day 5 and day 21 after the procedures. Conclusion: The patients with broadened time window on CDM who performed ERT may have a higher recanalization rate and relatively good clinical outcome. The patients with collateral circulation has good outcome.

Objective To study the clinical effect of SCOFIX on thoracolumbar fracture.Methods The clinical data of twenty-five cases with thoracolumbar fracture treated with SCOFIX system were retrospectively anal- ysed.Results With six to twenty-two months follow-up,anterior height of compressed vertebral bodies was restored from 46.8 %(12%～60%)preoperatively to 92%(90%～100%)postoperatively,and that of posterior height was from 77.5%(26%～86%)to 96.7%(90%～100%).Cobb's angle was from 15.7?(12?～26?)preoperatively to 1.4?(0?～6?)postoperatively.Conclusion SCOFIX system was simple structured,easily used and strongly fixed, and it was a good system in spinal internal fixation and for deeply reseach.

Objective To compare the postoperative effect of pars plana vitrectomy,phacoemulsification and intraoeular lens (IOL)implantation with silicon oil removed,phacoemulsification and IOL implantation.Design A retrospective case-control study.Par- ticipants 91 cases(104 eyes)of proliferative diabetic retinopathy with tractive retinal detachment or vitreous hemorrhage were per- formed cataract surgery with IOL implantation.Methods All patients were followed up average 6 months,in whom 52 eyes with pars plana vitrectomy,phacoemulsification and IOL implantation(combined group),and the other 52 eyes with silicon oil removed,pha- coemulsification and IOL implantation(sequential group).The differences of the postoperative visual acuity and inflammatory reactions of the anterior chamber between the two groups were analyzed.Main outcome measures Visual acuity and inflammatory reactions of the anterior chamber.Results There were 14/52 eyes with best corrected visual acuity more than 0.1 in combined group and 8/52 eyes in the sequential group after the surgeries(X~2=-6.87,P=0.07) .Corneal edema happened in 16/52 eyes in combined group and 6/52 eyes in sequential group 1 week after the surgeries(X~2=11.53,P=0.001).Keratic precipitate happened in 20/52 eyes in combined group and 9/52 eyes in sequential group after the surgeries(X~2=5.79,P=0.019) .Conclusions The incidence of postoperative anterior chamber in- flammation is higher in Phacoemulsification combined with pars plana vitrectomy group.

Foreign Bodies ; Glottis ; Humans

Hearing Loss, Sudden ; therapy ; Humans ; Hyperbaric Oxygenation ; adverse effects ; Male ; Middle Aged ; Neck ; Subcutaneous Emphysema ; etiology

Adult ; Aged ; Biomarkers, Tumor ; blood ; Blood Proteins ; analysis ; Breast Neoplasms ; blood ; diagnosis ; Female ; Humans ; Middle Aged ; Neoplasm Proteins ; blood ; Protein Array Analysis ; Proteomics ; methods ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Arrhythmias, Cardiac ; etiology ; Coronary Vessels ; pathology ; Humans ; Male ; Mediastinal Cyst ; pathology ; Young Adult

Factor Analysis, Statistical ; Health Policy ; Leadership ; Occupational Health Services ; organization & administration

Objective To investigate anti-oxidant activities of the n-butanol extract of Boschniakia rossica (BEBR), and preliminarily determine the material basis of its antioxidant activities. Methods Antioxidant activities of different polarity extraction of BEBR were performed by using 1,1-dipheny-2-trinitrophenylhydrazine (DPPH), 2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid), diammonium salt (ABTS) radical scavenging assays and ferric reducing anti-oxidant power as the index. The aging rats induced by D-galactose were used as models to investigate the effects of different n-butanol extract parts on the content of MDA and the activity of SOD and CAT in liver tissue; The chemical composition of BEBR was preliminarily analyzed by HPLC-DAD-ESI-MS/MS. Results BEBR had good scavenging effect on free radicals of DPPH and ABTS, and well performation in ferrous reduction experiments of FRAP determination. Compared with the model group, all indexes of MDA, SOD, and CAT in liver tissues of rats from different dose groups with BEBR were significantly improved (P < 0.01), which showed that levels of MDA reduced, the activity of SOD and CAT increased and back to above normal levels. The anti-oxidant activity in vivo showed in a dose-dependent manner. Nineteen chemical constituents were tentatively characterized by HPLC-DAD-ESI-MS/MS, of which 14 were phenylpropanoid glycosides (PPGs). Conclusion BEBR has good anti-oxidant effects and PPGs are the main active constituents.