3.Drug induced liver injury associated with Chinese herbal medicine and herbal related food supplements
Chinese Journal of Digestion 2001;0(07):-
Objective To investigate the drug induced liver injure(DILI)associated with Chinese herbal medicine and herbal related food supplements.Methods From 1982 to 2005.8.9 consecutive pa- tients were diagnosed as DILI based on their medication history,clinical manifestation,liver function and other laboratory tests.The final retrospection confirmatory diagnosis was made according to the interna- tional scoring system for DILI.Results The 82 DILI patients(28 men,54 females,age ranging from 16 to 81 years old)accounted for 2.2% of hospitalized patients with liver dysfunction.Among those patients with DILI,30.5% was caused by weight reducing drugs or food supplements,12.2% by drugs of derma tology,8.5% by drugs for cardiovascular disease,8.5% by drugs of rheumatology,7.3% by drugs of gynecology,6.1% by drugs for liver disease,6.1% by blood-lipids modulators,3.7% by drugs for thy- roid disease,3.7% by drugs for hyperplasia of mammary glands and 13.4 % by the others.The duration of medication was from 6 clays to 6 months and the incubation period was from 6 days to 3 months.DILI could be classified as acute hepatocellular injury(36.59%),acute cholestasis(39.02%)and mixtures (24.39%).About 10% patients were accompanied by allergic manifestations.All patients recovered rap- idly after stopping the relevant medicine.Conclusion Chinese herbal medicine and herbal related food supplements are a common cause of DILI in China.The awareness and monitoring improving DILI during herbs treatment is a critical issue in daily practice.
4.Bilateral laryngeal granulomas after endotracheal intubation.
Zhi-hong LIN ; Hua-lin WANG ; Hui-e WANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2007;42(1):67-68
Adult
;
Aged
;
Female
;
Granuloma, Laryngeal
;
etiology
;
Humans
;
Intubation, Intratracheal
;
adverse effects
;
Male
5.MicroRNA as prognostic biomarkers in prostatic cancer.
Chinese Journal of Pathology 2014;43(11):786-788
Biomarkers, Tumor
;
analysis
;
Humans
;
Male
;
MicroRNAs
;
analysis
;
Prognosis
;
Prostatic Neoplasms
;
chemistry
;
genetics
6.ENDOSONOGRAPHIC FEATURES OF MEDIASTINAL LYMPH NODES IN LUNG CANCER PATIENTS
Jiandong WANG ; Yu′E SUN ; Zhiqiang WANG ; Al ET ;
Medical Journal of Chinese People's Liberation Army 2001;0(07):-
The purpose of this study was to evaluate the features of mediastinal lymph nodes in lung cancer patients during endoscopic ultrasonography(EUS), and to establish the clinical method for the preoperative staging of lung cancer using EUS. The EUS patterns of 103 lymph nodes in 21 patients with lung cancer were evaluated. Confirmation of benign and malignant lymph nodes was obtained by surgical resection and pathology. The following features were compared between benign and malignant lymph nodes: short axis , long axis, distinct margins and the shape of nodes. The results showed that all of the lymph nodes were hypoechoic. Both the short axis greater than 1.0cm and distinct margins or round shape independently predicted malignant invasion ( P
9.Diabetic cardiomyopathy and autophagy.
Chunlei LIU ; Lili WANG ; Kunlun HE
Chinese Journal of Pathology 2015;44(2):146-149
10.Osteosarcoma of interatrial septum: report of a case.
Huanhuan CAO ; Hongyu XING ; Yang WANG
Chinese Journal of Pathology 2014;43(7):489-490