Objective:To explore the impact of continuous nursing education on the quality of life, psychological state and satisfaction of patients with inflammatory bowel disease based on micro-video.Methods:In chronological order, 83 patients with inflammatory bowel disease (hospitalized from January to June, 2019 in Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology) were divided into two groups, the control group with 42 cases (discharged from the hospital from January to March, 2019) carried out regular telephone continuing nursing education and the intervention group with 41 cases (discharged from hospital from April to June, 2019) were provided the continuous nursing education in the form of telephone plus micro-video. Before intervention and after 3 months of intervention, quality of life, levels of anxiety and depression and nursing satisfaction were evaluated by inflammatory bowel disease questionnaire (IBDQ), Self-rating Anxiety Scale(SAS), Self-rating Depression Scale(SDS), digital table method and compared between the two groups.Results:There was no significant difference in quality of life, levels of anxiety and depression before intervention between the two groups( P>0.05). After 3 months of intervention, the scores of IBDQ, SAS, SDS were 155.1±23.7, 58.7±15.1, 59.5±11.1 in the intervention group and 115.7±21.7, 71.5±16.7, 72.8±12.0 in the control group, the differences between the two groups were statistically significant ( t values were 7.910, 3.642, 5.223, P<0.01). The nursing satisfaction score was 89.32±6.34 in the intervention group and 81.45±7.21 in the control group, the difference between the two groups was statistically significant ( t value was -5.284, P<0.01). Conclusions:Continuous nursing education in the form of micro-videos can increase the quality of life of the inflammatory bowel disease patients, improve mental state and their nursing satisfaction in further.

Humans ; Pneumonia ; Pulmonary Fibrosis ; T-Lymphocytes, Regulatory ; Th17 Cells

Aortic Valve ; Fibroma ; Heart Neoplasms ; Humans

Aim To investigate the therapeutic value of fosinopril in heart failure.Methods Thirty SD rats were divided into three groups at random.Rats in heart failure group and fosinopril group were given an 8 weeks overswimming exercise to induce heart failure and the heart failure rats in fosinogril group were treated with fosinopril orally (2 mg?kg?d-1) for 6 weeks.14 weeks later the hemodynamic indexes, myocardiac apoptosis rate, left ventricular mass index (LVMI) and myocardiac interstitial fibrosis were determined.Results The hemodynamic indexes in heart group were remarkably different from those in normal control group, while there was a significant improvement in fosinopril group (P

0.05),but in ages(P

Adolescent ; Adult ; Aged ; Aged, 80 and over ; Female ; Gene Rearrangement, T-Lymphocyte ; Humans ; Lymphoma ; genetics ; Lymphoma, Extranodal NK-T-Cell ; genetics ; Lymphoma, Large-Cell, Anaplastic ; genetics ; Lymphoma, T-Cell, Peripheral ; genetics ; Male ; Middle Aged ; Polymerase Chain Reaction ; methods ; Young Adult

Humans ; Hypoxia-Inducible Factor-Proline Dioxygenases ; metabolism ; Ki-67 Antigen ; metabolism ; MicroRNAs ; metabolism ; Neoplasm Grading ; Neoplasm Staging ; Neprilysin ; metabolism ; Neuroendocrine Tumors ; classification ; diagnosis ; metabolism ; pathology ; surgery ; PAX8 Transcription Factor ; Paired Box Transcription Factors ; metabolism ; Pancreatic Neoplasms ; classification ; diagnosis ; metabolism ; pathology ; surgery ; Prognosis ; Tumor Suppressor Proteins ; metabolism

OBJECTIVETo investigate whether xuezhikang has additional beneficial effect on lipid peroxidation, myocardial fibrosis, inflammation and blood pressure control in hypertensive patients without sever hyperlipidemia treated with extended-released nifedipine.

METHODSThis is a randomized, single-blind, placebo-controlled study, 100 patients with primary hypertension (HT) and normal or lightly elevated cholesterol level were randomized to receive placebo (n=49) or xuezhikang (1200 mg/d, n=51) for 24 weeks on top of extended-released nifedipine (20 mg, bid), 30 healthy volunteers served as controls. Plasma was obtained at baseline and 24 weeks after therapy. Lipids, C-reactive protein (CRP), malondialdehyde (MDA), superoxide dismutase photo-inhibition rate (SOD-PR) and type I collagen carboxypropeptide (PIP) were measured.

RESULTSNormal blood pressure (<140/90 mm Hg) was found in 49 out of 51 xuezhikang treated patients and in 40 out of 49 placebo treated patients (P<0.01) after 24 weeks therapy. Plasma CRP, MDA, SOD-PR and PIP were significantly higher in HT patients than those in normal controls. Plasma CRP, MDA, PIP and SOD-PR were significantly decreased in xuezhikang group while remained unchanged in placebo group after 24 weeks treatment.

CONCLUSIONIn patients with primary hypertension without severe hyperlipidemia treated with nifedipine, xuezhikang treatment exerts additional beneficial effects including better blood pressure control, endothelial function improvement, lipid oxidation loading attenuation and anti-inflammation.

Cholesterol, HDL ; blood ; Cholesterol, LDL ; blood ; Drugs, Chinese Herbal ; therapeutic use ; Endothelium, Vascular ; physiopathology ; Humans ; Hypertension ; drug therapy ; Lipids ; blood ; Nitric Oxide ; blood ; Phytotherapy ; Single-Blind Method ; Treatment Outcome

Aged ; Benzylisoquinolines ; therapeutic use ; Bronchoalveolar Lavage ; Female ; Humans ; Male ; Middle Aged ; Oxidative Stress ; Phytotherapy ; Pneumoconiosis ; metabolism ; therapy ; Quality of Life ; Treatment Outcome

Adult ; Burns ; etiology ; Humans ; Male ; Middle Aged ; Paraquat ; adverse effects ; Scrotum ; injuries