No abstract available.
Ophthalmology*

Here, we report 3 cases of mixed tumor of the lacrimal gland. The age of the patients were 43, 26 and 35 respectively. The two of these were male and one female. The most outstanding complaint was exopthalmos. A mass was palpated on the orbit and eye ball deviation in downward position was present in all cases. Pathologic findings were mixed tumor of the lacrimal gland with no evidence of malignancy. These tumors were well encapsulated and any evidence of involving bone and soft tissue was not found. Modified Kroenlein-Berke operation was performed and tumor mass was removed entirely with finger dissection in all cases. The vision was not improved but the cosmetic result was satisfactorr.
Female ; Fingers ; Humans ; Lacrimal Apparatus* ; Male ; Orbit

There were many instances in which glaucoma, esp. primary, combined with hearing disturbance. The etiology of these cases has not been known until now. We had 15 primary glaucoma patients for whom pure tone audiometry wa~ performed, and could find the hearing defect in high tone in 5 cases (1/3 among those patients). The audiometric curve was similar to that in the presbycusis, but severer in degree than that occured within the normal physiological aging process. The average age was 62.4 year in the group with the hearing defect, and 45.6 year in the group without the hearing defect. There were no relationship between the hearing defect and intraocular tension, visual field change, glaucomatous cupping, and duration of glaucoma. These results may support the opinion of the authors that the hearing disturbance in glaucomatous patients is related to the arterioscIerotic changes which aggrevate the presbycusis, and not related to glaucoma itself. On the otherhand, however, it is stilI impossible for us to rule out that the pleiotropic and multifactorial genetic factors may play as a common important role in the hearing disturbances and glaucoma. And further studies would be necessary for these problems.
Aging ; Audiometry ; Glaucoma* ; Hearing* ; Humans ; Presbycusis ; Visual Fields

The tension lowering effects of Diamox and other carbonic anhydrase inhibitors are well known and they are widely used against a various forms of glaucomas. This paper deals with the clinical experiences in normal and glaucomatous human eyes with Diamox-Sequels, kindly supplied by Lederle Laboratories and Yuhan Corp. MATERIALS AND METHODS: Normal healthy persons, 15 females and 20 males, were studied on their 45 eyes. Glaucomatous disease had been ruled out by careful examinations of intraocular pressure, visual fields and fundus. They had been also checked for the diurnal variations of intraocular pressure during the daytime. One capsule (500mg) of Diamox Sequels was given to each individual and the changes in the intraocular pressure were studied at various time intervals up to 53 hours after the administration. Tonometry was carried out by the Goldmann's applanation tonometer. The effects of Diamox Sequels on the glaucomatous eyes were studied in the same way. The glaucomatous eyes included 10 eyes of 7 chronic simple glaucoma patients, 5 eyes of 3 chronic narrow-angle glaucoma patients and 5 eyes of 5 secondary glaucoma subjects. They received one capsule of Diamox Sequels and the intraocular pressure was measured one or two times daily. The results of long-term treatment were also studied by daily administration of one capsule of Diamox Sequels, follow-up periods being from 3 to 19 days. No medication, oral or local, of antiglaucomatous drugs were allowed for at least 3 days prior to this study. The differences due to age, sex and type of glaucoma were not considered here. At the same time, the effects of a single 500mg of ordinary Diamox tablet were studied in normal ~md glaucomatous eyes. RESULTS: (1) Normal eyes. The intraocular pressure began to fall 1 hour after the administration. The tension gradually fell and the maximal reduction of tension occurred after 9.8 hours and the extent of maximal fall was 4.5mm Hg on the average, 29.4 % of the original intraocular pressure. The tension gradually rose and returned to the original level between 23~50 hours (average 43 hours). Side effects were noted in 4 cases, e.g., 11.4 %. (2) Glaucomatous eyes. The effects were noted within the first 1~2 hours and became maximal after 13 hours, the extent of the maximal fall 40.1 % of the original pressure, e.g., 16.2 mmHg. The original tension was restored after 30 hours. By long-term administration of Diamox Sequels, 8 eyes(40 %) showed excellent results, their intraocular pressure maintained below 21 mmHg. Sede-effects were noted in 3 cases(20.0 %). COMMENTS: The effects of Diamox Sequels and Diamox tablet on normal and glaucomatous subjects were summarized in table 1. As shown, Diamox Sequels has the longer duration of hypotensive actions and the time of maximal fall of intraocular pressure delayed considerably, as compared with Diamox tablet. In almost all cases, its action continued for more than 24 hours. In glaucomatous eyes, the time of maximal reduction of ocular tension was slightly later and the maintenance of low tension was slightly shorter than those in normal eyes. The extent of the maximal fall, however, was almost the same after administration of Diamox Sequels and Diamox. Side effects were encountered in 11~20% of cases by Diamox Sequels, and in 40-60% of cases by Diamox. This is one of the most striking advantages of Diamox Sequels over Diamox. Thus it is concluded that Diamox Sequels has the longer hypotensive actions and fewer side effects.
Acetazolamide* ; Carbonic Anhydrase Inhibitors ; Female ; Follow-Up Studies ; Glaucoma ; Glaucoma, Angle-Closure ; Glaucoma, Open-Angle ; Humans ; Intraocular Pressure ; Male ; Manometry ; Strikes, Employee ; Visual Fields

A study on the pathologic findings after recession and resection of extraocular muscles in rabbits was performed. Fibrosis of the extraocular muscles increased with time, which showed no difference between the recessed and resected muscles. Inflammation and foreign body reaction decreased with time, which showed no difference between the recessed and resected muscles. Adhesions of extraocular muscles to the sclera were observed from one month after the operation. The resected muscles showed milder adhesion to the sclera than the recessed ones. The operated extraocular muscles showed atrophies at one month, which showed no difference between the recessed and resected muscles. According to our results, when reoperation is needed, fibrosis of the extraocular muscles after recession and resection should be considered when making a decision on the amount of muscle to be recessed and resected.
Animals ; Atrophy/etiology ; Fibrosis/etiology ; Foreign-Body Reaction/pathology ; Inflammation/etiology/pathology ; Oculomotor Muscles/pathology/*surgery ; Postoperative Complications/*pathology ; Rabbits ; Reoperation

After general anesthesia with intra-venous pentothal sodium, half of the optic nerve was sectioned on both sides with special care to preserve vessels of the optic nerve. To observe retrograde degeneration of the optic nerve, the animals were sacrifised 1, 2, 3, 4, and 5 weeks after nene section. Eye ball and optic nerve was removed and fixed in 10% formalin solution. Eye baIl and optic nerve was cut and stained with Hematoxylin Eosin and Luxol Fast Blue stain for light microscopic examination. Until 2 weeks. no significant pathologic changes were observed. Specimens 3 weeks after optic nerve section showed decreased retinal ganglion cell numbers and gliosis and myelin loss in optic nerve and these changes were intensified on 4th and 5th weeks specimens. So, I observed the followings: 1. Retrograde degeneration of the optic nerve occurred simultaneously through out the length of the nerve fibers instead progressively from the cut end toward the ganglion cell. 2. The retrograde degeneration of the optic nerve started 3 weeks after section.
Anesthesia, General ; Animals ; Atrophy* ; Eosine Yellowish-(YS) ; Formaldehyde ; Ganglion Cysts ; Gliosis ; Hematoxylin ; Myelin Sheath ; Nerve Fibers ; Optic Nerve* ; Rabbits* ; Retinal Ganglion Cells ; Retrograde Degeneration ; Sodium ; Thiopental

The author studied the 240 cases of strabismus patients in our OPD from 1972 to 1976. And the author observed the results of occlusion therapy in 55 cases of amblyopia with strabismus. The results are as follows: The sex distribution in exotropia patients showed a preponderance in female sex, the ratio male to female being 2:3. Concerning the refractive status, there were more hyperopia in esotropia and more myopia in exotropia. The amount of deviation was about the same at the near and distance, most patients had a basic type and distributed between 21-40 prism. Of all patients in whom a determination of the retina correspondence could be made, 70% showed NBC and 25 % showed ARC 5% showed variable. Ninety percent of the strabismic amblyopia patients was successfully treated by occlusion therapy. A positive correlation was not found between the duration of occlusion and the age at which occlusion was started. Amblyopes showed arrest of improvement after a certain period, about 3 to 4 months. The exotropia patients over the age of 7 showed good results by occlusion. The shorter the time between the age at which occlusion was started and the onset of strabismus, the better was the result. Strabismic amblyopia responded well to conventional occIusion.
Amblyopia ; Esotropia ; Exotropia ; Female ; Humans ; Hyperopia ; Male ; Myopia ; Retina ; Sex Distribution ; Strabismus*

Macroscopic and microscopic examinations were performed on the 18 rabbit eyes in which methyl methacylate and nylon looped methyl methacrylate anterior chamber lenses were inserted and fixed in the chamber angle. Methyl methacrylate lens was inserted in 9 eyes and nylon looped methyl methacrylate was inserted in 9 eyes. Macroscopically, corneal haziness was not completely disappeared untill 7 ~ 10 days after insertion and neovascularization was found near the limbus where lens was fixed in the chamber angle. Microscopically, fibrosis and infiltration of neutrophil leucocytes were found on the cornea adjacent to the angle, chamber angle and iris. These findings were slightly more pronounced in nylon looped anterior chamber lens group. From this result, we can not draw any conclusion regarding prolonged effect of these anterior chamber lenses and further investigation will be needed.
Anterior Chamber* ; Cornea ; Fibrosis ; Iris ; Neutrophils ; Nylons

There have been many problems in the treatment of exotropia. Especially, recurrence is very often while overcorrection is troblesome problem in the correction of recurrent exotropia. Considering less change in postoperative divergence at reoperation than at first operation, we performed unilateral lateral rectus recession in recurrent exotropia. Among the 40 patients who underwent recession and resection of horizontal recti in one eye and then unilateral lateral rectus recession in fellow eye because of recurrent exotropia greater than 15 delta, the cases who were followed more than three months were analyzed retrospectively. Forty patients were eligible. The male to female ratio was 13:27. The mean angle of recurrence was 21.4 delta regardless of the angle of first operation, and mean recurrence time was 18.8 months. The amount of divergence from postoperative 1 day to 3 or 4 month was 11.7 delta at first operation, 0.0 delta at second operation. Sixty five percents at 3 or 4 month. 60.9% at 6 or 8 month, and 55.6% at 12 or 14 month postoperatively showed stability within 10 delta. Among the 18 cases who were able to be tested fusion, 10 cases showed fusion with Worth 4-dot test(55.6%).
Exotropia* ; Female ; Humans ; Male ; Recurrence ; Reoperation ; Retrospective Studies

In this study, we reviewed 46 consecutive patients with diagnosis of Duane's retraction syndrome at the Seoul National University Hospital from April, 1987 to October, 1995. The following characteristics were reviewed - sex, laterality, clinical type, primary position alignment, anomalous vertical movements, head turn, fusion and amblyopia. The incidence in each sex showed no difference(male: 54%, female:46%). Ninety-six percent of cases had a unilateral manifestation and 4% of cases had bilaterality. The left eyes were involved in 70% of cases and the right eyes in the 26% of cases. Type I was the most common type(96%) and the esodeviations were the most frequent in primary position. Head turns were observed in 77% of cases and the direction of head turns were toward the involved eyes in esodeviations, and away from the involved eyes in exodeviations regardless of the clinical types. Among 26 patients who underwent the fusion test, seventeen patients(65%) had fusion and that was more common in patients with exodeviation(83%) than others.
Amblyopia ; Diagnosis ; Duane Retraction Syndrome* ; Esotropia ; Exotropia ; Head ; Head Movements ; Humans ; Incidence ; Seoul