No abstract available.
Ophthalmology*

Here, we report 3 cases of mixed tumor of the lacrimal gland. The age of the patients were 43, 26 and 35 respectively. The two of these were male and one female. The most outstanding complaint was exopthalmos. A mass was palpated on the orbit and eye ball deviation in downward position was present in all cases. Pathologic findings were mixed tumor of the lacrimal gland with no evidence of malignancy. These tumors were well encapsulated and any evidence of involving bone and soft tissue was not found. Modified Kroenlein-Berke operation was performed and tumor mass was removed entirely with finger dissection in all cases. The vision was not improved but the cosmetic result was satisfactorr.
Female ; Fingers ; Humans ; Lacrimal Apparatus* ; Male ; Orbit

The tension lowering effects of Diamox and other carbonic anhydrase inhibitors are well known and they are widely used against a various forms of glaucomas. This paper deals with the clinical experiences in normal and glaucomatous human eyes with Diamox-Sequels, kindly supplied by Lederle Laboratories and Yuhan Corp. MATERIALS AND METHODS: Normal healthy persons, 15 females and 20 males, were studied on their 45 eyes. Glaucomatous disease had been ruled out by careful examinations of intraocular pressure, visual fields and fundus. They had been also checked for the diurnal variations of intraocular pressure during the daytime. One capsule (500mg) of Diamox Sequels was given to each individual and the changes in the intraocular pressure were studied at various time intervals up to 53 hours after the administration. Tonometry was carried out by the Goldmann's applanation tonometer. The effects of Diamox Sequels on the glaucomatous eyes were studied in the same way. The glaucomatous eyes included 10 eyes of 7 chronic simple glaucoma patients, 5 eyes of 3 chronic narrow-angle glaucoma patients and 5 eyes of 5 secondary glaucoma subjects. They received one capsule of Diamox Sequels and the intraocular pressure was measured one or two times daily. The results of long-term treatment were also studied by daily administration of one capsule of Diamox Sequels, follow-up periods being from 3 to 19 days. No medication, oral or local, of antiglaucomatous drugs were allowed for at least 3 days prior to this study. The differences due to age, sex and type of glaucoma were not considered here. At the same time, the effects of a single 500mg of ordinary Diamox tablet were studied in normal ~md glaucomatous eyes. RESULTS: (1) Normal eyes. The intraocular pressure began to fall 1 hour after the administration. The tension gradually fell and the maximal reduction of tension occurred after 9.8 hours and the extent of maximal fall was 4.5mm Hg on the average, 29.4 % of the original intraocular pressure. The tension gradually rose and returned to the original level between 23~50 hours (average 43 hours). Side effects were noted in 4 cases, e.g., 11.4 %. (2) Glaucomatous eyes. The effects were noted within the first 1~2 hours and became maximal after 13 hours, the extent of the maximal fall 40.1 % of the original pressure, e.g., 16.2 mmHg. The original tension was restored after 30 hours. By long-term administration of Diamox Sequels, 8 eyes(40 %) showed excellent results, their intraocular pressure maintained below 21 mmHg. Sede-effects were noted in 3 cases(20.0 %). COMMENTS: The effects of Diamox Sequels and Diamox tablet on normal and glaucomatous subjects were summarized in table 1. As shown, Diamox Sequels has the longer duration of hypotensive actions and the time of maximal fall of intraocular pressure delayed considerably, as compared with Diamox tablet. In almost all cases, its action continued for more than 24 hours. In glaucomatous eyes, the time of maximal reduction of ocular tension was slightly later and the maintenance of low tension was slightly shorter than those in normal eyes. The extent of the maximal fall, however, was almost the same after administration of Diamox Sequels and Diamox. Side effects were encountered in 11~20% of cases by Diamox Sequels, and in 40-60% of cases by Diamox. This is one of the most striking advantages of Diamox Sequels over Diamox. Thus it is concluded that Diamox Sequels has the longer hypotensive actions and fewer side effects.
Acetazolamide* ; Carbonic Anhydrase Inhibitors ; Female ; Follow-Up Studies ; Glaucoma ; Glaucoma, Angle-Closure ; Glaucoma, Open-Angle ; Humans ; Intraocular Pressure ; Male ; Manometry ; Strikes, Employee ; Visual Fields

There were many instances in which glaucoma, esp. primary, combined with hearing disturbance. The etiology of these cases has not been known until now. We had 15 primary glaucoma patients for whom pure tone audiometry wa~ performed, and could find the hearing defect in high tone in 5 cases (1/3 among those patients). The audiometric curve was similar to that in the presbycusis, but severer in degree than that occured within the normal physiological aging process. The average age was 62.4 year in the group with the hearing defect, and 45.6 year in the group without the hearing defect. There were no relationship between the hearing defect and intraocular tension, visual field change, glaucomatous cupping, and duration of glaucoma. These results may support the opinion of the authors that the hearing disturbance in glaucomatous patients is related to the arterioscIerotic changes which aggrevate the presbycusis, and not related to glaucoma itself. On the otherhand, however, it is stilI impossible for us to rule out that the pleiotropic and multifactorial genetic factors may play as a common important role in the hearing disturbances and glaucoma. And further studies would be necessary for these problems.
Aging ; Audiometry ; Glaucoma* ; Hearing* ; Humans ; Presbycusis ; Visual Fields

In the margial myotomy of inferior oblique muscle(IO myotomy), only the overaction of the muscle is eliminated and the normal action of the inferior oblique saved. Steroid is usually used to prevent the adhesion of the tissue after IO myotomy, subconjunctivally. The myotomy of IO was performed in 14 white rabbits which were divided into two groups, one group having local injection of triamcinolone after IO myotomy and the other not having it. At postoperative 1 month, there were edema of the muscle fibers and infiltration of the inflammatory cells. Three months postoperatively, ingrowth of fibrous tissue and atrophy of the muscle fibers were found. Those changes were less prominent in the group with triamcinolone injection. This study revealed that subconjunctival triamcinolone injection after the IO marginal myotomy produce a good effect on the prevention of postoperative adhesion in the long term.
Atrophy ; Edema ; Rabbits* ; Triamcinolone*

40 patients who were diagnosed as the palsy of the third, fourth and sixth cranial nerve at Seoul national university hospital, were evaluated to reveal the etiology and clinical feature. The palsy of sixth cranial nerve is most common, and those of third and fourth cranial nerve followed it. Trauma was the most common cause of the palsy of the third, fourth, and sixth cranial nerve. Most of the palsy of the third cranial nerve involved both upper and lower branch, and aberrant regeneration was observed at 8 cases and its major cause was also trauma. The palsy of sixth cranial nerve was more frequently accompanied other cranial nerve palsy than those of the other two. Average recovery rate was 44.8% and, that of the sixth cranial nerve was higher than those of the other two.
Abducens Nerve Diseases* ; Abducens Nerve* ; Cranial Nerve Diseases ; Humans ; Oculomotor Nerve ; Paralysis ; Regeneration ; Seoul ; Trochlear Nerve

In order to evaluate the incidence of lateral incomitance after monocular recession and resection and compare the amount of correction achieved by monocular recession and resection according to the gaze direction and distance in exodeviations, we measured the angle of deviation in primary, right, left, up, down and near gaze before and after monocular recession and resection. Lateral incomitance was developed in11.4%(9/79) after monocular recession and resection. The amount of correction of the deviation toward the side of operated eye was larger than that of the deviation in primary position(p=0.002), but the amount of correction of the deviation toward the side of non-operated eye, up, down and near gaze was all smaller than that of the deviation in primary position(all, p<0.01).
Exotropia* ; Incidence

In 33 patients with congenital superior oblique palsy, we examined whether patients fixed with paretic or nonparetic eye in primary, head tilted positions to the right and left, and whether they could fuse in the characteristic head tilt postion or not. Of the 33 patients, 27 had horizontal deviation, 21 had vertical deviation and 17 had both horizontal and vertical deviation. There were 10 'V' patterns in 13 bilateral cases. In unilateral cases, both the paretic and nonparetic eye could be the fixating eye in primary position. There was a tendency to fix with right eye in the left head tilt, with left eye in the right head tiltin both the unilateral and bilateral cases. Twelve ot the 13 patients could not fuse with Worth 4 dot test preoperatively even in head tilted position.
Head ; Humans ; Paralysis*

Foveal hypoplasia has been described in association with aniridia, albinism, microphthalmia and achromatopsia. Isolated foveal hypoplasia unassociated with other ocular abnormalities has been rarely reported and is regarded as a rare condition. Authors experienced two cases of isolated foveal hypoplasia in the same family. A 30-year-old woman and her 3-year-old daughter presented with a complaint of poor visual acuity and nystagmus. Ophthalmoscopic examination of their both eyes revealed loss of foveal reflex, absence of macular luteal pigment, and abnormal distribution of retinal vessels at the posterior pole. No abnormal ocular findings other than lens opacity, high myopia, and large optic cup were found.
Adult ; Albinism ; Aniridia ; Cataract ; Child, Preschool ; Color Vision Defects ; Female ; Humans ; Microphthalmos ; Myopia ; Nuclear Family ; Reflex ; Retinal Vessels ; Visual Acuity

Optic neuritis is an acute inflammatory disease of the optic nerve. Visual loss in optic neuritis is typically sudden and accompanied visual field defects. We attempted to characterize the clinical manifestations of optic neuritis based on visual acuity and visual field changes. Eighteen patients were included in this study who completed at least 3 month follow-up. we observed these patients with no medication in ten, with oral prednisolone in seven and with intravenous methylprednisolone in one. Statistically significant visual recovery occurred at first and second month and twenty eyes of 27 eyes (74%) had improved o.5 or more. Most common type of visual field defect was central scotoma (74%) and 85% of eyes who showed abnormal visual fields at first visit recovered normal visual field during follow-up period.
Follow-Up Studies ; Humans ; Methylprednisolone ; Optic Nerve ; Optic Neuritis* ; Prednisolone ; Scotoma ; Visual Acuity ; Visual Fields