OBJECTIVE: Neurologic complications make a major contribution to morbidity and mortality in kidney transplant recipients. Most occur months or years after transplantation and may never come to the attention of the transplant surgeon. We report 5 cases of neurologic complications in kidney transplant recipients. Three of them were diagnosed as intracranial abscess by central nervous system infection and others were diagnosed as hypertensive encephalopathy. CASES: Three patients with intracranial abscess have experienced mild coughing, intermittent fever and pulmonary infection initially. During the treatment of pulmonary infection they experienced some of neurologic symptoms and signs, such as severe headache, loss of consciousness and dizziness. Brain MRI was performed and showed lesions of intracranial abscess. The etiologic organism were Nocardia in two cases and Staphylococcus epidermidis in one case. They were treated with stereotactic aspiration of abscess and antibiotics therapy. Two of them recovered but eventually one of them didn't recover. Two patients with hypertensive encephalopathy experienced severe headache, visual illusion and generalized seizure at the immediate postoperative period of kidney transplantation. Their systolic pressure was 190~210 mmHg and diastolic pressure was 140~150 mmHg. Brain MRI scan showed hyperintensity signals in T2WI and hypointensity signal in T1WI on bilateral occipital lobes. They were treated with antihypertensive agents and anticonvulsants. Seizure were well controlled and didn't recur. CONCLUSION: Meaningful survival in post-transplant neurologic complications is dependent on rapid diagnosis and initiation of effective treatment.
Abscess ; Anti-Bacterial Agents ; Anticonvulsants ; Antihypertensive Agents ; Blood Pressure ; Brain ; Brain Abscess ; Central Nervous System Infections ; Cough ; Diagnosis ; Dizziness ; Fever ; Headache ; Humans ; Hypertensive Encephalopathy ; Illusions ; Kidney Transplantation ; Kidney* ; Magnetic Resonance Imaging ; Mortality ; Neurologic Manifestations ; Nocardia ; Occipital Lobe ; Postoperative Period ; Seizures ; Staphylococcus epidermidis ; Transplantation* ; Unconsciousness

INTRODUCTION: Hypertension is a key modifiable risk factor for myocardial infarction and stroke, yet medication adherence remains low. The ongoing COVID-19 pandemic has further complicated the management of chronic diseases like hypertension. This study aimed to explore the correlation between the patient-doctor relationship and medication adherence among hypertensive Filipinos aged 40-65 years in the Greater Manila Area during the pandemic. METHODS: A cross-sectional study was conducted involving 131 hypertensive Filipino participants. Data were collected through an online survey, assessing participant demographic and medical profiles, medication adherence using the Hill-Bone Compliance Scale (HBCS), and the patient-doctor relationship using the Physician-Doctor Relationship Questionnaire-9 (PDRQ-9). RESULTS: Approximately half of the participants demonstrated good adherence to hypertension medication. A weak but significant positive correlation was found between overall medication adherence and the patient-doctor relationship. The duration of anti-hypertensive drug intake also showed a weak positive correlation with medication adherence. Factors such as comorbidities and type of consultation did not significantly impact medication adherence. CONCLUSION This study emphasizes the significance of the patient-doctor relationship in medication adherence among hypertensive Filipinos during the COVID-19 pandemic. Enhancing communication and trust between patients and physicians can potentially improve medication adherence and overall disease management.
COVID-19 ; hypertension ; medication adherence ; perception ; anti-hypertensive agents ; cross- sectional

Persistent autonomic hyperfunction is not well-recognized disease entity. Recently the authors experienced one case following hypertensive intracerebral hemorrhage in the basal ganglia. It was manifested as storms of hypertension, tachycardia, hyperthermia, severe diaphoresis, hyperventilation and decerebrate posture. Extensive investigations on infection, pheochromocytoma or status epilepticus revealed no abnormalities. Medications including antibiotics, antipyretics and antiepileptic agents were administered, but in vain. However, intravenous morphine infusion managed to stabilize his conditions. To our knowledge, the present case is the first one to be thermographed, and is the second case next to Rossitch's report of autonomic dysfunction following intracerebral hemorrhage.
Anti-Bacterial Agents ; Anticonvulsants ; Antipyretics ; Basal Ganglia ; Cerebral Hemorrhage ; Fever ; Hypertension ; Hyperventilation ; Intracranial Hemorrhage, Hypertensive* ; Morphine ; Pheochromocytoma ; Posture ; Status Epilepticus ; Tachycardia

Antihypertensive tea (AHT) was processed from Flos Sophorae, Folium Nelumbii, Radix Achyranthis Bidentatae, Radix Codonopsis Pilosulae, Flos Chrysanthemi, … in the form of filtered bag (3g/bag). Experimental study on subchronic toxicity showed that AHT was non-toxic. Clinical trial carried on 60 patients with hypertension (stages 1 and 2) receiving 9g (3 bags)/day for 30 days revealed that AHT produced good effects: blood tension reduced by 88.3%, clinical symptoms significantly improved, better changes in biochemical and hematological parameters, no side effects
Antihypertensive Agents ; Antihypertensive Agents ; Tea ; Disease

We studied 47 ischemic stroke patients with hypertension at the ICU-Quang tri general hospital in the year 2004. These patients were divided into 2 groups: group A consisting of 23 patients whose blood pressure was lowered considerably within 6 early hours and 24 early hours after admission; while the blood pressure of 24 patients of group B was lowered step by step, in a ladder fashion according to the recommendation of WHO. Objective: Clinical comparison (improvement of coma and movement, evidence of cerebral edema) between the 2 groups within 72 hours after hospitalization. Study design: prospective, clinical comparison between 2 disease groups. Results:-Upon admission, the difference of mean Glasgow scores of group A(8.71.1) and group B (8.31.9) is not of statistical significance (p>0.05). At the 24th hour, the mean Glasgow scores of group A and B are 7.5 2.4 and 9.52.6, respectively. By 48 hours, these scores of group A and B are 7.82.4 and 10.62.7, respectively. The mean Glasgow scores of group A and B at the 72nd hour are 7.51.5 and 11.32.5, respectively. It is demonstrated that the mean Glasgow scores at hours 24, 48 and 72 of group B are statistic significant higher than these scores of group A (p<0.01). The clinical improvement of motor paralysis and cerebral edema within 24, 48 and 72 hours after hospital admission is better in group B than in group A, with statistic significance (p<0.01).
Stroke ; Hypertension ; Antihypertensive Agents

Objectives: finding a drug with rapid hypotensive effect, little adverse effects, easy to use for malignant and paroxysmal hypertension, concurrently compare the effects of Adalate in patients who were treated with one or more antihypertensive drugs that their blood pressure were not reduced to the normal level with this in patients who be used only Adalate. Subjects: 50 patients with ages of 18- 80 diagnosed as primary hypertension phase II (10 patients) and phase III (40 patients). Results: 48 patients have a good corresponding with Adalate. Both the diastolic and systolic blood pressures were reduced. The side effects were not common.
Hypertension ; Antihypertensive Agents

Subjects: liquid extraction (1/1) of acaranthus; frog; dog; rabbit; mice. Method: effects of extraction on blood pressure of dog (effects on adrenaline and nicotine), on isolated heart of frog, on the narcotic effect of hexobarbital in mice. Results: Liquid extraction has synergic effect with hexobarbital, rapid and long hypotension because of adrenaline blocking (a partly block of gland of autonomic nervous system) and vasodilator
Hypertension ; Antihypertensive Agents

Evaluation on the hypotensive action and preliminary finding about active mechanism of "hypotensive tisane" in experimental animals. The trial performed on the dogs shown that "hypotensive tisane" were used at dose of 4g/kg have rapid, long effect and decrease heartbeat. In addition, it had effects on strong vasodilatation, and on the process of lymphocyte form change, and antibacterial effect with some bacteria and fungus
Hypertension ; Antihypertensive Agents

Subjects: The patients who were 16 years of old or more and diagnosed with mild (stage I) and moderate (stage II) hypertension. Method: Open, compared and controlled study. The study group involved 40 patients who performed qi-exercises for 45 minutes per day on 30 days. Control group included 33 patients used fludex. It was found that qi-exercises, but not fludex, had increased the duration of wave-E. There was significant increase of total diastolic duration in study group, but not in control group. Qi-exercises did not change significantly the peak of atrial systole-induced left ventricular filling flow velocity, but fludex provided significant decrease. Left ventricular dystolic function of subjects in study groups did not change, comparing with baseline.
Hypertension ; Antihypertensive Agents

A study on the effects of "antihypertensive tea" in the experimental mice has shown that the anti hypertensive tea reduced the natural activities of mice but had no hypnotic effect. The tea had synergic effect when combining with hexobarbital in lasting the sleep duration. The tea at dose of 0.05 - 0.2 ml/10g of body weight of mice (higher 5-20 times of clinical dose) had sedative effect.
Antihypertensive Agents ; Tea