It is generally accepted that Kasai operation is the best treatment for biliary atresia (BA). The implementation of early screen plan improves the age threshold at the suitable time point of Kasai operation. This is the key issue to improve the survival rate of autologous liver in biliary atresia. The monitoring of stool color card, B-ultrasonography and serum con?jugated bilirubin can be used for preliminary seeming biliary atresia. It is very important to improve the ability of basic unit medical staff for major improvements to the understanding of the significance of biliary atresia. In some country and district, the local government has put the screen list for BA into healthcare booklet for children. Thus, it has a significant impact of early screen plan on the diagnosis and treatment of BA, and it can improve the BA autologous liver survival time. So far, there is still no BA early screen plan in the nationwide. We should pay attention to BA, and establish early screen system in different local health unit quickly.

OBJECTIVE To estimate the current situation about nosocomial infections(NI),and find possible reasons to improve measures.METHODS A point-prevalence survey of NI in all inpatients was made on June 11,2007.RESULTS Of the 755 patients investigated,the prevalence rate of NI was 4.77%(36 cases).In all of the NI occurred,the common sites of NI were respiratory tract(69.30%),superficial surgical incision(13.80%),and skin soft tissue(8.33%).The usage rate of antibiotics was 57.40%,The single usage rate of antibiotics was 60.70%,double antibiotics usage 38.30%,and triple antibiotics usage 0.90%.CONCLUSIONS The departments of nephrology and neurosurgery are with high NI rate.Strengthening the management of severe patient and rational using antibiotics can help to reduce prevalence rate of NI.

OBJECTIVE To investigate the resistance of the isolated staphylococci to erythromycin and clindamycin and the frequency of inducible clindamycin-resistance of the isolates. METHODS The susceptibilities of erythromycin and clindamycin of the isolates were examined by Kirby-Bauer disc agar diffusion test and the inducible clindamycin-resistance was detected by D-zone test.Cefoxitin disk diffusion test was used for detection of meticillin-resistant staphylococci. RESULTS Among the total of 219 staphylococcus strains,119(54.34%) were resistant to both erythromycin and clindamycin(cMLS) and 45(20.55%) were resistant to erythromycin but susceptible to clindamycin and showed positive D-test results(iMLS).In the phenotype of resistant to erythromycin but susceptible to clindamycin the rates of inducible clindamycin-resistance of MRSA,MSSA,MRCNS and MSCNS were 64.71%,54.55%,70.37% and 60.00%,respectively. CONCLUSIONS.D-test should be performed to find erythromycin-resistant and clindamycin-susceptible isolates of staphylococci.

Objective To study the chemical constituents of starfish Asterias rollestoni Bell.Methods The constituents were isolated by chromatography methods and identified by spectroscopic and chemical analyses.Results and Conclusion A novel compound was obtained and identified as(2S,3S,4R)-2-(13'-methyl-pentadecanoylamino)-nondecane-1,3,4-triol.The compound was reported first time and named as rollceramide A.

Objective To investigate the expression and clinical significance of high-sensitivity C-reactive protein(hs-CRP) and interleukin-6 (IL-6) in patients with recurrence of atrial fibrillation(AF) after radiofrequency catheter ablation.Methods Retrospective analysis was made among a total of ninety-seven cases of paroxysmal atrial fibrillation treated by radiofrequency catheter ablation in Chaoyang Central Hospital from January 2011 to December 2015.The patients were divided into recurrent group and successful group,depending on whether they had recurrence in six months after radiofrequency catheter ablation.The concentration of the patients'' serum hs-CRP and IL-6 before radiofrequency catheter ablation were detected and compared with those of the healthy subjects (control group) during the same period.Logistic regression analysis was used to analyze the risk factors in atrial fibrillation recurrence after radiofrequency catheter ablation.Results The levels of serum hs-CRP was (4.6±1.2) mg/L and IL-6 was(0.19±0.05) mg/L in the recurrent group,higher than those in the control group ((2.0±0.3) mg/L,(0.10±0.03) mg/L).The differences between the two groups were statistically significant (P=0.037,0.046).According to the atrial fibrillation recurrence,97 patients were divided into recurrent group (29 cases) and successful group (68 cases).The levels of serum hs-CRP and IL-6 in the recurrent group were (5.61±2.30) mg/L,(0.30±0.07) mg/L,respectively,while the data of the successful group were (3.29±1.62) mg/L,(0.15±0.06) mg/L,respectively.There were significant differences between the two groups (P=0.047,0.036).Logistic regression analysis showed that the left ventricular anterior and posterior diameter (OR=2.073,95%CI:1.078~4.126,P=0.031),levels of serum hs-CRP (OR=1.943,95%CI:1.025-3.698,P=0.042) and serum IL-6 (OR=2.071,95%CI:1.089-10.101,P=0.027) were all risk factors in atrial fibrillation recurrence after radiofrequency catheter ablation.Conclusions Inflammatory factors might be involved in the occurrence and maintenance of atrial fibrillation.The expression levels of serum hs-CRP and IL-6 are related to the recurrence of AF,which could be independent predictors of postoperative atrial fibrillation recurrence.

Objective:To explore the efficacy of iodized lecithin in treatment of macular edema. Methods:From February 2014 to February 2015,a total of 66 patients(66 eyes) with macular edema in our hospital were divided into control group(n=33) and ob-servation group ( n = 33 ) randomly. Iodized lecithin combined with conventional therapy was applied in observation group, and conventional therapy was applied in control group. Observed the change of best corrected visual acuity( LogMAR BVCA) and central macular thickness(CMT) in the two groups pre and post treatment,and observation on clinical curative effect of the two groups at 6 month after treatment. Results:Compared with pre-treatment,the average value of LogMAR BVCA and CMT in the two groups showed significantly decreased at 1, 2, 3, 6 months after therapy ( P< 0. 05 ) . Compared with control group, the observation group could significantly decrease the average value of LogMAR BVCA and CMT at 2,3,6 months after therapy (P< 0. 05). After 6 months of treatment,the total effective rate of observation group showed significantly higher than control group (P< 0. 05). Conclusion: Iodized lecithin combined with conventional therapy have a significant curative effect to improve vision,promote regression of macular edema, and enhance the treatment effect. It’s worthy of clinic application.

OBJECTIVE:To establish a method for the simultaneous determination of andrographolide,quercetin-3-O-gluco-side,dehydroandrographolide and kaempferol-3-O-glucoside in Compound chuanxinlian tablet. METHODS:HPLC was performed on the column of Phenomenex C18 with mobile phase of acetonitrile- 0.1% phosphoric acid aqueous(gradient elution)at a flow rate of 1.0 ml/min,the detection wavelength was 225 nm for andrographolide,335 nm for quercetin-3-O-glucoside and 254 nm for de-hydroandrographolide and kaempferol-3-O-glucoside,column temperature was 25 ℃,and the volume injection was 10 μl. RE-SULTS:The linear range was 0.111-2.770 μg for andrographolide(r=0.999 9),0.064-1.605 μg for quercetin-3-O-glucoside (r=0.999 9),0.086-2.138 μg for dehydroandrographolide(r=0.999 9)and 0.050-1.260 μg for kaempferol-3-O-glucoside(r=0.999 9);the limits of quantitation were 0.48 ng,0.88 ng,0.93 ng and 1.03 ng,the limits of detection were 0.79 ng,1.15 ng,0.96 ng and 1.07 ng,respectively;RSDs of precision,stability and reproducibility tests were lower than 2.0%;recoveries were 96.57%-100.30%(RSD=1.3%,n=9),95.04%-98.87%(RSD=1.3%,n=9),95.74%-102.92%(RSD=2.4%,n=9) and 96.73%-100.95%(RSD=1.6%,n=9),respectively. CONCLUSIONS:The method is sensitive,reliable and reproducible,and can be used for the si-multaneous determination of andrographolide,quercetin-3-O-glucoside,dehydroandrographolide and kaempferol-3-O-glucoside in Compound chuanxinlian tablet.

This paper gives an overview of the "German School" of functionalist translation theory,and analyses its characteristics and advantages in guiding translation teaching.On the basis of that,the author holds that this theory has great significance to current translation teaching in China.

Clinical teaching is an important part of teaching which has a bearing on the level of medical teaching and the quality of personnel training. The clinical teaching ability of young physicians is related to the whole teaching process. So Young physicians should be a serious clinical teacher with good medical ethics, strict clinical thinking, formal clinical skills.

This paper,through comparative analysis,studies the features of non-English major students of medical universities as the translation subjectivity in translation teaching,in the hope that it will provide translation teaching with pertinent reference.