Objective To explore the clinical application of array comparative genomic hybridization (aCGH) and karyotype a-nalysis in the prenatal evaluation of fetal with small supernumerary marker chromosome (sSMC) .Methods One case was indenti-fied with de novo small supernumerary marker chromosome .G-banding analysis indicated that the fetus had a karyotype of 47 , XY ,+Mar .aCGH was used to define the precise location and size of de novo chromosome .Results aCGH revealed that there was 2 .03 Mb duplication from 15q11 .1-q11 .2 in the fetus .aCGH revealed the presence of small supernumerary marker chromosome . Conclusion The technologies of aCGH can be used for identifying the origin of small supernumerary marker chromosome and defi-ning the loci of the chromosome .Combined with the karyotype analysis ,it can be applied to genetics analysis and prenatal diagnosis .

OBJECTIVE: To identify the incidence and the risk factors for emergence agitation (EA) in adults undergoing general anesthesia for nasal surgery. METHOD: We examined 674 patients aged ≥ 18 years who underwent general anesthesia for nasal surgery between February 2013 and February 2015. The patients were divided into control group (518 cases) and EA group (156 cases) by Sedation-agitation scale (SAS) method. Demographic and clinical variables were assessed and the data were analyzed by multiple logistic regression analysis. RESULT: The overall incidence of emergence agitation was 23. 15%. Significant difference was observed between EA and the control group in many aspects, such as sex, age, ASA classify, smoking history, history of cerebrovascular disease, preoperative anxiety, the use of midazolam, anesthesia means, postoperative pain, postoperative analgesia, presence of a tracheal tube, and presence of a urinary catheter. The results of multiple logistic regression analysis indicated that the occurring of EA was significantly correlated with younger age, male, preoperative anxiety, inhalation anesthesia, postoperative pain, presence of a tracheal tube, and presence of a urinary catheter, while seniors, with the use of midazolam, total intravenous anesthesia, analgesia and natural awakening were protective factors. CONCLUSION EA following general anesthesia is a common complication in patients with adult nasal surgery. To reduce the occurrence and consequences of agitation episodes, elimination of the associated risk factors is necessary, especially in patients with risk factors.
Adult ; Age Factors ; Analgesia ; Anesthesia Recovery Period ; Anesthesia, General ; adverse effects ; Anesthesia, Inhalation ; Anxiety ; Female ; Humans ; Incidence ; Male ; Midazolam ; therapeutic use ; Nasal Surgical Procedures ; Pain, Postoperative ; Psychomotor Agitation ; physiopathology ; Risk Factors

Objective To investigate the application value of high-sensitivity troponin T (hs-cTnT)in acute coronary syndrome (ACS).Methods Serum hs-cTnT,CK and CK-MB were detected 198 patients with chest pain including 105 cases of acute myocar-dial infarction(AMI)and 93 cases of unstable angina(UA),and 83 cases of healthy physical examination as control.Results The positive rates of hs-cTnT,CK and CK-MB in the patients with diagnosed AMI were 88.6%,48.6% and 71.4% respectively,which were significantly higher than those in the patients with UA and the healthy controls(P <0.05 ).The positive rate of hs-cTnT in early AMI patients was higher than that of CK and CK-MB.Conclusion Compared with CK and CK-MB in myocardial Zymogram, hs-cTnT has very high sensitivity and specificity for diagnosing myocardial injury,could reduce the misdiagnosis and missed diagno-sis of ACS and is a marker for diagnosing the myocardial injury in early ACS.

Objective To evaluate the effects ofYinhuangdecoction and external application ofXilei decoction in treating vesicular stomatitis.Methods From January 2012 to October 2013, 126 enrolled cases were randomly divided into a treatment group and a control group with 63 in each. The treatment group, which was treated with acycloguanosine tablets as the control group did, was additionally given orallyYinhuang decoction and external application ofXilei decoction. The symptoms, clinical effects comparison were observed before and after the treatment.Results After 7-days treatment, the cure rate of the treatment group was 95.2%(60/63), and the control group was 73.0%(46/63). Their difference was conspicuous(χ2=17.407,P<0.05). The treatment group attained better curative effects(P<0.05) and got shorter symptomatic relief time of the duration of fever, time of tain disappeared, time of ulcer dissipated and cure time(The T-value is respectively 9.590, 6.983, 5.864, 5.814,P<0.01).ConclusionsYinhuang decoction and external application ofXilei decoction is effective for treating vesicular stomatitis.

The gradually matured MOOC technology and its platform will promote a new round of teaching reform and innovation of information retrieval microcourse .The teaching model of information retrieval microcourse against the background of MOOC and its implementation were described with the practical teaching model of information re-trieval microcourse in Shihezi University as an example .Its problems were summarized with suggestions put forward for their solution .

With Indian ink vasoperfusion and microangiography,the vessel rebuilding in fresh xenogenic bone graft of 33 rabbits,which had been given glucocortiocoid for a short period of time has observed.The results were as follows:(1)The vessel rebuilding ofxenogenic bone marrow was formed by the hostbone vessel growing in, however,that of the compact bone was formed by the inward penetration of the vessels from the host periost.(2)with glucocorticoid having been used for a short period of time,the vessel rebuilding rate was almost the same between fresh xenogenic bone and autogenic bone.(3)Vessel invasion which happened before osteogenesis regulated osteogenic action. The vessel invasion of different or- igins and under different conditions may have different influence on osteogenesis and osteolysis.

23 freshly removed breast tumors without any therapy were studied. Argyrophlilic nuclcolar organizer region proteins (AgNORs) were observed by frozen sections and imprints and the distribution and shape of some AgNORs were analyzed by means of electron microscope. It was found that AgNORs in benign lesions showed regular dotted granules and mean individual counts were significantly fewer (3.33?1.19) than that (9.21?1.24) ( P

The renal histopathological findings of the 71 cases with complete clinical histories were observed, 40 cases developed clinically hepatorenal syndrome, including 11 cases with functional renal failure and 29 cases with acute tubular necrosis.Moreover the former was liable to convert into the latter in coures of time.It was suggested that hepatorenal syndrome should be defined as a complication of advanced liver diseases such as extensive liver cirrhosis, hepatoma, fulminant heptitis,etc.,characterised by acute renal failure with oliguria and azotemia, which pathologically may be shown as functional renal failure or acute tubular necrosis.This paper discussed the pathogenesis of functional renal failure and acute tubular necrosis, the relationship between renal failure and histologic changes of kidneys, as well as the prognosis of hepatorenal syndrome.

By histochemical methods of AKPase, ACPase, 5'-Nase, NSE and SDH, 10 cases of human hepatocellular carcinoma (HCC) and its surrounding liver tissue were investigated. Generally, these enzyme activities in HCCs obviously decreased or completely disappeared, neverthless in one case, the AKPase of HCC showed notable activity, and in another case, the ACPase activity also marked.The surrounding liver tissue either in cirrhosis or in hepatic fibrosis appeared normal hepatic enzymatic activity. The differences of enzymes between HCCs and their surrounding liver tissues were distinct.

Because of the medical industry valla,the medical market is in a state of oligopoly.Hospitals and patients are in a state of asymmetric information in the medical market,which could lead to moral hazard,adverse selection,and low social and medical efficiency.Based on the gaming model,we analyze the gaming process and equilibrium between hospitals and patients under the circumstances of asymmetric information.The analyzing result suggests that asymmetric information in the medical market is harmful for patient's benefit and the development of medical market as well.Therefore,it's necessary to strengthen the entire social medicare,set up an opening system of medical information and strengthen the national health education so as to relieve the asymmetric information between hospitals and patients,and improve the efficiency of medical market.