1.Imaging Diagnosis of Malignant Intestinal Lymphoma
Zuoxian LIU ; Yangyu OU ; Fajin LV ; Xiaoming ZHONG
Journal of Practical Radiology 2001;0(01):-
Objective To explore the imaging characteristics of malignant lymphoma of intestinal tract.Methods Thirty-two cases of malignant intestinal lymphoma proved operatively and pathologically were studied .All cases were subjected to Ba-meal or double contrast Ba-enema examinations. There were 10 cases studied by CT scan and 19 cases by B-ultrasonography.Results By Barium studies we found 20 cases of lesions involving the small intestine or ileocecal junction and 12 involving the large intestine. In the former subgroup , we found regional dilatation of small intestine in 6, multiple intraluminal polypoid filling defects in 7, intestinal wall infiltration in 4, intraluminal nodular proliferation with ulcer formation in 3; while in the latter subgroup ,there were polypoid masses seen in 6, narrowing of intestinal lumen in 5 and coarse intestinal mucosa in 1.On CT scan , we found irregular thickening of intestinal wall in 5 cases , eccentric intraluminal mass in 2 and intestinal dilatation associated with thickening of intestinal wall in 3. B-ultrasonography showed beltoid low echo thickened intestinal wall in 5 cases ,pseudo kidney sign in 6 and lumpy low echoes in 2. Conclusion Barium study , CT scan and B-ultrasonography have different specific diagnostic characteristics for malignant intestinal lymphoma.In combination with these examinations are mutually beneficial in the diagnostic process.
2.Expression of TNF-? mRNA in hypertrophic myocardium by pressure overload in rats
Xingli SU ; Guangdao GAO ; Xiucheng LUO ; Zuoxian WANG ; Xinfeng WANG ; Jinjun LIU ; Yuanxi LIN
Chinese Journal of Pathophysiology 2000;0(08):-
AIM: To observe the change of TNF-? mRNA in hypertrophic cardiac myocytes induced by pressure overload in rats and the effect of captopril. METHODS: Serum and heart were collected 42 days after the cardiac hypertrophy model made by pressure overload by abdomen aorta-constriction (AC). Hypertrophic parameter and the concentration of TNF-? in serum and left ventricle were determined by ELISA. TNF-? mRNA in cardiac myocytes was determined by in situ hybridization and analyze by ELIA image analysis system. The orientation of (TNF-?) mRNA in cardiac myocytes was also observed. RESULTS: Left ventricle hypertrophy was observed 42 days after operation. TNF-? mRNA in AC group elevated 98% compared to sham-operated group and descended 64.14% by captopril ((P