Objective:To explore the effect of type D personality and perceived control on experiential avoidance in patients with coronary heart disease (CHD) , so as to provide a basis for reducing their experiential avoidance.Methods:From December 2018 to August 2019, a total of 365 patients with CHD who were admitted and treated in a ClassⅢ Grade A hospital in Anhui Province were selected as research objects by convenient sampling method. Type D Personality Scale-14 (DS-14) , Control Attitudes Scale-Revised (CAS-R) , Acceptance and Action Questionnaire 2nd Edition (AAQ-Ⅱ) were used to investigate those patients.Results:Among the 365 patients with coronary heart disease, 128 were type D personality, accounting for 35.1%. The score of CAS-R was (25.18±5.73) and that of AAQ-Ⅱ was (21.61±5.99) . Multiple linear regression showed that the negative emotions and social inhibition of type D personality, perceived control and residences had predictive effects on experiential avoidance in patients with CHD, and the joint explanation variation was 47.0%.Conclusions:The experiential avoidance of patients with CHD needs to be improved. Clinical nurses should actively assess whether patients with CHD have type D personality and help patients improve their perceived control so as to reduce their experiential avoidance.