Cardiovascular Diseases ; diagnosis ; Humans ; Magnetic Resonance Imaging

Humans ; Non-alcoholic Fatty Liver Disease

The purpose of this clinical study was to evaluate the protective effect of continuous potassic warm blood perfusion on myocardium during warm blood extraeorporeal circalation. Warm blood cardiopulmonary bypass and continuous potassic warm blood perfusion for myocardial protection were used in 39 cases undergoing coronary bypass. 15% potassium chloride was mixed with oxygenated warm blood for continuous myocardial perfusion to induce cardiac arrest. The average nasopharyngeal temperature was maintained at 33.5℃. The warm blood was delivered at a rate of 150 to 200 ml/min; 15% potassium chloride was pumped at a high flow rate of 120 to 160 ml/h and then at a low flow rate of 15 to 20ml/h when electrocardiogram showed straight line. The results showed that 38 cases (97.4%) had spontaneous return of normal sinus rhythm shortly after removal of the aortic crossclamp. Myocardial positive inotropic agents were seldom used and hemodynamics kept stable. Cardiac functions showed fast recovery and there were not serious complications such as perioperative myocardial infarction, low output syndrome and arrhythmia. It is indicated that continuous potassic warm blood perfusion for myocardial protection may have a remarkable results to prevent myocardial anoxemia and reperfusion injury during CPB.

Coronary Stenosis ; etiology ; pathology ; Diagnostic Imaging ; Humans

Objective To explore the effect of appreciation intervention on anxiety and complications in patients with renal biopsy. Methods A total of 197 cases of renal biopsy patients were divided into the control group (n=96) and the observation group (n=101). The observation group was given comprehensive nursing intervention with appreciation, the control group was only given comprehensive nursing care, the two groups were evaluated with Zung Self-rating Anxiety Scale (SAS) upon admission and 1 week after puncture. Results After intervention, the SAS score of the observation group was 30.87 ± 4.52, and the SAS score of the control group was 32.32 ± 3.72, and the difference between the two groups was statistically significant (t=2.45,P<0.05). Totally 97 patients in the observation group and 78 cases in the control group received bed urination exercises, and the difference between the two groups was statistically significant (χ2=9.412,P<0.01). The complications of two groups were collected, the complications in the observation group were 27 cases, and the complications in the control group were 50 cases, the difference between the two groups was statistically significant (χ2=13.285,P<0.01). Among the postoperative complications, 8 of the patients in the observation group had urinary retention, and 19 of the control group had urinary retention (t=2.446,P=0.015). In the observation group, 3 cases had abdominal distention, and 10 cases in the control group suffered from abdominal distension (t=2.117, P=0.035). In the observation group, 1 case had low back pain, and 6 cases in the control group suffered from lumbago (t=2.004, P=0.047); the difference was statistically significant. Conclusions Appreciate intervention for patients with renal puncture biopsy has a positive impact on the bed urination exercise in puncture before surgery. It can alleviate the anxiety of patients received renal biopsy, reduce urinary retention, abdominal distension and pain complications, and improve bedridden experience.

Adolescent ; Adult ; Audiometry, Pure-Tone ; Ear Protective Devices ; utilization ; Humans ; Middle Aged ; Noise, Occupational ; prevention & control ; Young Adult

Objective To evaluate the double-balloon enteroscopy(DBE) for obscure gastrointestinal bleeding(OGIB) and evaluate the health economics under the guidance of DBE for surgical treatment of obscure gastrointestinal bleeding.Methods A total of 114 patients,whose hemorrhage etiology could not be determined by conventional gastroscopy,enteroscopy and gastroenterography,underwent DBE.With pathological results as diagnostic criteria,the value of double-balloon enteroscopy for obscure gastrointestinal bleeding diagnosis was studied.Results The sensitivity,specificity and accuracy of DBE for OGIB were 85.86％,63.63％,81.57％,respectively.The positive likelihood ratio was 2.36 and the negative likelihood ratio was 0.22.The total days of hospitalization,hospital costs,cost of hospital drugs were lower in the DBE group than in the control group(27.2 ± 11.8 days VS 16.4 ±5.3 days,35 690.2 ±3 466.5 Yuan VS 19 409.3 ± 9 253.2 Yuan,17 805.8 ± 2 145.5 Yuan VS 9 133.0 ± 4 664.9 Yuan) (all P ＜ 0.05).Conclusion DBE plays an important role in diagnosis of OGIB.It has significance in clinic,health economics,and social benefits.

OBJECTIVE： To study the pharmacokinetics and relative bioavalability of omeprazole capsules in humans.METHODS： 18 male healthy volunteers orally took domestic omeprazole capsules and losec capsulles(used as control)40mg respectively.Blood concentrations of drugs were determined by HPLC.RESULTS： Times to reach the peak levels of omeprazole and losec were （2.10± 0.64） h and （1.88± 0.70） h， the peak plasma concentrations were （895.64± 553.07） ng/ml and （974.67± 554.93） ng/ml and the areas under the drug concentration curves were （1 971.88± 1 220.98 ） ng/（h· ml） and （2 057.60± 1 306.32） ng/（h· ml） respectively.CONCLUSION： The two capsules have the same bioequivalence.

Objective To evaluate the effects of rehabilitation training according to Brtmnstrom stage on ability of daily life (ADL) and motor function of stroke patients. Methods 120 bemiplegia patients who suf-fered from stroke were randomly divided into the observation group and the control group with 60 cases in each group. Both groups received routine cerebrovascular medicine treatment and routine nursing, the observation group received rehabilitation training according to Brannstrom stage(including body position,simple kinesithera-py,daily life exercise), psychological nursing and health guidance. The motor function and ADL were as-sessed respectively by Brurmstrom assessment and Barthel index before and 4 weeks after training using rank test. Results Brurmstrom stage and ADL of the observation group were better than those of the control group after rehabilitation training. Conclusions Early rehabilitation training according to Bnmnstrom stage can obviously improve the recovery of motor function and ADL as well as life quality of stroke patients.

Objective To explore the effect of educational mode on children' s social adaptive capacity (SAC) through investigating its change of children into kindergarten one year later. MethodsFor this study, participants were divided into three groups, namely study group (SG), control group Ⅰ ( CG Ⅰ ) and control group Ⅱ( CG Ⅱ ). ①SG :30 ～ 47-month-old children at their entrance at one kindergarten of Xi' an city were study by the follow-up study method. There were 119 participants in this trial except 22 lost- visitors. The scores of children's SAC were evaluated at their entrance time and one year later respectively, according to the Social Adaptation Scale for Infant-Junior Middle School's Student Revised by Zuo Qi-hua. ②Control group(CG) :The children,whose classes were randomized,of five classes were divided into CG Ⅰ and the other four classes were CG Ⅱ. There were 107children aged at 30 ～ 46 months in CC Ⅰ , 94 children aged at 42 ～ 59 months in CG Ⅱ. The scores of their SAC were also evaluated according to the same scale on September 2006. The cross-section investigation were used to CG Ⅰ and CG Ⅱ. Results① The mean total score of SAC in SG was higher at one year later ( 10. 52 ± 0.77 ) than that at their entrance time( 10.22 ±0.52) (P＜0.01) ,and the total score of SAC in SG was lower at their en trance time than that of CG Ⅰ (10.49 ±0.06)(P＜0.01 ). ②There was no significant difference in children's SAC between SG at the final stage( 10. 52 ± 0.77 ) and CG Ⅱ(10.40 ± 0.67 ) (t = 1.500, P ＞ 0.05). ③There were no significant difference in children's SAC between boarding care mode( 10.34 ± 0.68 ) and day care one( 10.32 ±0.56) (t = 0.182, P ＞ 0.05 ). ④There were no significant difference in children' s SAC between male ( 10.42 ±0.73) and female( 10.51 ±0.68) in the kindergarten.. ConclusionThe gathered living mode can promote the child SAC development, and the boarding care mode or day care one in one year has no effect on children' s SAC.