The incidence of severe acute pancreatitis (SAP) is increasing year by year,and the mortality is high,which poses a great threat to the life of patients.In recent years,the immune nutrition therapy has become the focus in the treatment of SAP,among which,fish oil lipid emulsion as a novel type of fat emulsion,has the multi-effects of anti-inflammatory,anti-oxidative,immunomodulatory,promoting signal transduction and protecting organ function apart from providing nutrition and regulating metabolism.It can prevent the deterioration of the whole body from systemic inflammatory response syndrome (SIRS) to multiple organ dysfunction syndrome (MODS and ultimately improve the prognosis of patients.

Breast cancer is the most common type of cancer among women in China and around the world. Population-based survival analysis can reflect the overall level of cancer prevention, diagnosis, and treatment in countries or regions, providing basic information for making efficient health policies. Breast cancer survival varies among countries or regions because of differences among races, so-cioeconomic factors, healthcare services, and cancer diagnosis and treatment. Breast cancer prognosis is closely related to tumor stage, status of receptors, and treatments. By determining the relationship between breast cancer survival and related factors, the re-sults can help in predicting the prognosis and evaluating the quality of care services. The article provides an overview of breast cancer survival in China and abroad, as well as references for cancer surveillance.

Objective To analyze the monitored results of the influenza from 2010 to 2014 in Huainan city, and to master the local status of influenza and the dynamic changes of this kind of epidemic,which can get us to find the outbreaks promptly.In the meantime,to provide the scientific basis for the further prevention.Methods 11 600 cases of patients with influenza like disease in Huainan were collected and viral nucleic acid was analyzed by using the method of detecting RealTime RT -PCR.Results From 2010 to 2014,3 633 cases were collected in Huainan General Hospital.PCR showed that 472 cases were positive(the positive rate was 13.0%),of which 187 cases were Seasonal H3 model(39.6%),91 cases were New type H1N1(19.3%),82 cases were B type(17.4%)and 81 cases were Yamagata type(17.2%).Conclusion From 2010 to 2014,the influenza was more active in the autumn and winter seasons in Huainan,and steady in other seasons.The H3 type is the main season separation plants.

miRNA is a kind of endogenous non-coding short RNA. Mature miRNA was formed through the process of shearing and transporting after genetic transcription. miRNA exhibits many important biological functions through regulating expression and translation of target mRNAs. Different miRNAs may act as oncogenes or antioncogenes, and have tissue specificity. The progress of the tumorigenesis is usually accompanied by expression-profile changes of miRNAs. MiRNA regulates many tumor biological behaviors such as differentiation, proliferation, apoptosis, invasion, metastasis, and drug resistance of tumors. Furthermore, some miRNAs have clinical significance in predicting prognosis of tumor patients.

BACKGROUND: It is always the key issue of rheumatoid arthritis(RA) to treat articular gall. A kind of medicine with favorable therapeutic effects and safety is urgently needed in the clinics. 99Tc-methylene diphosphonate 99(Tc-MDP) receives generalized attentions on its therapeutic effects and safety since its application into RA therapy.OBJECTIVE: To explore the characters of 99Tc-MDP in the amelioration of articular dysfunction in RA patients.DESIGN: A before-and-after controlled study by employing patients as subjects.SETTING: Department of rheumatism and immunology of an affiliated hospital of a university.PARTICIPANTS: Totally 67 patients with RA at active phase including 11males and 56 females aged between 29 and 71 years old with the course of disease between 9 and 78 months and admitted by the Department of Rheumatism of Huaxi Hospital Affiliated to Sichuan University were in accordance with the RA diagnostic criteria established by American Rheumatism Association(ARA) in 1987. Serious heart,liver or kidney dysfunction,active gastrointestinal pathological changes, hematology and endocrinology diseases,allergic complexion,and women during pregnancy or breast-feeding period were eliminated.METHODS: Clinical indicators including articular edema index, articular pain,grip,morning stiffness duration,rest pain,erythrocyte sedimentation rate (ESR) and C reactive protein(CRP) were compared before and after therapy in 67 cases received 99Tc-MDP treatment. Integrated evaluation was performed after the completion of therapy. Effective meant 30% of improvement in symptoms and physical signs,and reduction in ESR and CRP. Side effects were observed and recorded simultaneously. Data were statistically analyzed.RESULTS: After 99Tc-MDP treatment,RA condition significantly improved,as well as each clinical indicator including articular edema index,articular pain index,morning stiffness duration,rest pain,ESR and CRP(P<0.05) . The total clinical effective rate of this medicine was 81% and the incidence of side effects was small and mild.CONCLUSION: 99Tc-MDP can ameliorate the articular dysfunction of RApatients,which is a safe medicine with strong effect.

Objective To analyze the application value of digital radiography (DR) on healthy population.Methods 1449 cases of health examination on chest by DR were retrospectively studied,the physical examination results were analyzed.Results The medical examination of positive rate was 4.9％.The positive rate of women was higher than men ( x2 =11.493,P =0.001 ).the top 5 detection rate of diseases were lung old lesions,pneumonia,suspicious tumor,thickening and adhesion of pleural,senile pulmonary.Conclusion The DR examination was selected according to symptoms,medical history of participate in the examination,the check frequency was selected according to age.

Objective To observe the dynamic levels of IL-2,IL-5 and IL-6 produced by Balb/ c mice infected with DEN_2 clinical strains and to study their relation.Methods The Balb/c mouse in- feetion model was established by multiple-site subcutaneous injection with various doses of DEN_2 clini- cal strain.Mouse plasma samples collected from different experiment groups at various time after in fection were tested for IL-2,IL-5 and IL-6 levels with sandwich ELISA.Results After primary in- feeted with DEN_2 B strain,the levels of IL-2,IL-5 and IL-6 of all experimental groups were not sig- nificantly higher than the normal control group while the levels of experimental groups increased sig- nificantly after re-infection.The level of IL-2 reached to peak[average value of(101 522.44?10 465.375)pg/ml]at the 4th day after re-infection(the 20th day after the primary infection),and then the level gradually reduced.The levels of IL-5 in the Balb/c mice of the group 1 and 2 reached to peak at the 1st day after re infection(the 16th day after the primary infection),and there was signifi- cant difference between these two groups and the control group(P＜0.05).The levels of IL-6 in all experimental groups reached to peak at the 1st and the 2nd day after re-infection.The peak value of the third group is the highest comparing with the normal control group(P＜0.05).Conclusion Th2 response was predominant in the second infection phase.