Clinical skills training is an important part of medical students' training, which requires the selection of appropriate evaluation tools. At present, the direct observation of procedural skills (DOPS) and mini clinical evaluation exercise (Mini-CEX) are widely used, however, it is not comprehensive to use only one of the tools for evaluation. Based on the application situation of DOPS and Mini-CEX in clinical skill assessment at home and abroad, this paper will elaborate the combined application of DOPS and Mini-CEX in clinical teaching and standardized residency training for resident physicians, so as to make more comprehensive and systematic evaluation.