1.Prevention of neurotoxicity by high-dose folinic acid rescue after high-dose methotrexate and intrathecal methotrexate without compromising cure inspite of previous transient leukoencephalopathy after intrathecal methotrexate.
Alias HAMIDAH ; Raja Juanita Raja LOPE ; Zarina Abdul LATIFF ; Zulfiqar M ANUAR ; Rahman JAMAL
Annals of the Academy of Medicine, Singapore 2009;38(8):743-744
Child
;
Folic Acid
;
administration & dosage
;
therapeutic use
;
Folic Acid Antagonists
;
adverse effects
;
Hematinics
;
administration & dosage
;
therapeutic use
;
Humans
;
Hypesthesia
;
chemically induced
;
drug therapy
;
Injections, Spinal
;
Leukoencephalopathies
;
chemically induced
;
Male
;
Methotrexate
;
adverse effects
;
Quadriplegia
;
chemically induced
;
drug therapy
;
Time Factors
;
Vitamin B Complex
;
administration & dosage
;
therapeutic use