AIM To investigate the clinical effects of Modified Shugan Qingzhi Decoction on patients with type 2 diabetes mellitus complicated with dyslipidemia.METHODS One hundred and sixty patients were randomly assigned into control group(80 cases)for 8-week intervention of conventional treatment,and observation group(80 cases)for 8-week intervention of both Shugan Qingzhi Decoction and conventional treatment.The changes in clinical effects,lipid metabolism indices(TC,TG,LDL-C,HDL-C,Chemerin,ApoA1,ApoB,LPa),glucose metabolism indices(FBG,2 hPG,HbA1c),irisin,food ingestion inhibitor-1,TCM syndrome scores and incidence of adverse reactions were detected.RESULTS The observation group demonstrated higher total effective rate than the control group(P＜0.05).After the treatment,the two groups displayed increased HDL-C,irisin(P＜0.05),and decreased TC,TG,LDL-C,Chemerin,ApoA1,ApoB,LPa,glucose metabolism indices,food ingestion inhibitor-1,TCM syndrome scores(P＜0.05),especially for the observation group(P＜0.05).No significant difference in incidence of adverse reactions was found between the two groups(P＞0.05).CONCLUSION For the patients with type 2 diabetes mellitus complicated with dyslipidemia,Modified Shugan Qingzhi Decoction can safely and effectively regulate glucose and lipid metabolism and levels of irisin,feeding inhibition factor-1,Chemerin.

Objective To study the influence of nasal irrigations on the postoperative curative effect of patients with chronic sinusitis.Methods Total of 357 patients who suffered from chronic sinusitis received transnasal endoscopic surgery from 2008 to 2010 with 184 patients selecting nasal irrigations for the following treatments.Patients were followed up at two weeks,six weeks and four months after the surgeries via telephone.The symptoms of nasal obstruction,nasal discharge and headache were recorded and SNOT-20 was used to measure the quality of life.Results Symptoms of patients were improved,but improvement in nasal irrigations group was better than that in non-nasal irrigations group.Four months later,the average symptom score of nasal obstruction in nasal irrigations group was [0(0,1 )] which was significantly lower than [ 0( 0,1 )] in non-nasal irrigations group ( Z =- 3.176,P ＜ 0.05).The average symptom score of nasal discharge in nasal irrigations group was [0(0,2)] which was significantly lower than [0(0,2)] in non-nasal irrigations group (Z =- 4.403,P ＜ 0.05 ).The average score of headache was [ 0 ( 0,1 ) ] in nasal irrigations group and [ 0 (0,2) ] in non-nasal irrigations group,and the difference was statistically significant ( Z =- 4.539,P ＜ 0.05 ).Conclusions Nasal irrigations can improve symptoms of patients with chronic sinusitis and reduce the rectrrence.