1.Defibrillation efficacy of a newly developed automated external defibrillator in a swine ventricular tachycardia/fibrillation model.
Jie HUI ; Yun-Fei GU ; Xiao-Mei WU ; Zong-Cheng ZHU ; Jian-Ping SONG ; Xiang-Jun YANG ; Zhi-Hua LIU ; Ting-Bo JIANG ; Zu-Xiang FAGN ; Wen-Ping JIANG
Chinese Journal of Cardiology 2009;37(9):845-848
OBJECTIVEThe aim of this study was to evaluate the recognition and defibrillation efficiency of a newly developed automated external defibrillator (AED).
METHODVentricular tachycardia (VT)/ventricular fibrillation (VF) was induced by alternating current (50 Hz) through an electrode placed on apex of right ventricle in 23 anesthetized swine and recorded, recognized and defibrillated by a newly developed AED.
RESULTSA total of 96 VF was induced and 145 defibrillations were recorded. We analyzed available 167 electrocardiosignal with a total length of 103,740 seconds. The accuracy, sensitivity and the specificity of the AED on VT/VF recognition are 99.5%, 98.2% and 99.6%, respectively. The success rate of defibrillation was 33.4% which increased in proportion to defibrillation energy. The defibrillation threshold of energy is 29.10-116.91 (78.75 +/- 35.64) J, the defibrillation threshold of electric quantity is (0.11 +/- 0.04) C and the defibrillation threshold of voltage is (1216.67 +/- 260.87) V.
CONCLUSIONSThis newly developed AED has high sensitivity and the specificity on recognizing VT/VF. The lower success rate of defibrillation of this AED is associated with the low defibrillation energy during defibrillation which needs to be improved on further development.
Animals ; Defibrillators ; Disease Models, Animal ; Electric Countershock ; Equipment Design ; Sensitivity and Specificity ; Swine ; Ventricular Fibrillation ; therapy
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