1.Study result on anti-radical actvity and membrane endurance of otgontenger resorts
Oldokh S ; Ambaga M ; Myagmarbaatar G ; Zorigtbaatar D
Mongolian Medical Sciences 2011;172(2):129-133
Introduction: Although the physic-chemical nature and compounds of Otgontenger spring have been relatively studied over the last years, no any substantial scientific work was done in regard to its therapeutic action and significance.It is known that during gastritis, chronic hepatitis and rheumatism macro and micro elements and biologically active compounds dramatically decrease within cells of each related organ and the processes of cell’s bioenergy, bio-synthesis, and re-synthesis [1.2] are imbalanced that leads to loss of cell’s divisibility and its rejuvenescence. Consequently, disbalance in blood coagulation, micro-circulation, ischemia, hypothermia, reperfusion substantial decrease of endurance to anti-oxidant deficiency and anti-radical activity weakness are observed. So, our study has been done basing on our hypothesis that macro and micro elements as well as biologically active compounds in Otgontenger resorts as sulphate ion (SO42-), azotes (N2), hydrosulfuric acid (H2S), oxygen (О2), carbonate ion (СO32-), chloral ion (CL-), hydrogen (Н2), carbonic acid (СО2,) could replace the biologically regulative agents which are cardinally shortened and becoming the main factor of pathologies [3. 4].Goal: The goal of this study is to investigate treatment activity “Otgontenger” resorts treatment experimental conditions. It is purposed to define the redoxy-potentiality and anti-radical activities of Otgontenger resorts.Materials and Methods: The study was conducted at the Central Scientific Laboratory of Monos Medical University between 2009-2011. Otgontenger mineral water was transported in a package accordingly to the Mongolian Standard “The Technical requirements to mineral water of treatment and drinking intent” (MNS 3651: 2005). In order to determine the anti-radical activity of the mineral water each portion of the studying water is dissolved in ethanol. After that 0.1 and 0.2 mlg are taken from these solutions and are added to 1.5 mlg of alfa, alfa-demetilpicril-gydralice suspension. The solution is shaken well and once color deeply changed it was defined at 517 HM through spectrophotometer by B.Yu. Kulikov’s method (1995, 1996). In regard to Osmos’s endurance property, 16 white experimental rabbits are taken by mouth 1.0 mlg/200 grams each from the mineral water number 1 of the 1st group, number 18th of the 4th group and number 47th of the 7th group respectively two times a day for the consecutive five days. The blood is taken and centrifuged in a way that serum is segregated and 0.5 mlg of 10 percent erythrocytes is separated. Consequently, 5.0 mlg of distilled water is added and hymolize is carried out. Once gymolize is fully done, supernatant is separated after centrifuge and absorption is measured at 420hm by spectrophotometer. In regard to defining hydropereoxide endurance, the white rabbit is taken by mouth 1.0 mlg/200 grams each from the mineral water number 1 of the 1st group, number 18th of the 4th group and number 47th of the 7th group respectively two times a day for the consecutive five days. The blood is centrifuged and serum is segregated. The blood is taken and centrifuged in a way that serum is segregated and 0.5 mlg of 10 percent erythrocyte is separated. Consequently, 3.0 mlg of Н202 is added and hymolize is carried out. Once gymolize is fully done, supernatant is separated after centrifuge and absorption is measured at 420hm by spectrophotometer.Results: It has been defined that antiradical activity in the erythrocytes’ 4th compartment of the white rabbits taken mineral water number 18th of the 4th group and number 1st of the 1st group increased by 1.11-1.12 times compared to the group not taken, whereas, decreased by 1.1 times by the impacts of the mineral water under 47th number of the 7th group (Table 1). It is shown that the mineral water has effects to increase proton flows at mitochondria membranes and donators’ oxidation, because antiradical activity of the second compartment of the rabbit’s erythrocytes has gone down by 1.13-1.16 times compared to the group not taken because of the mineral water under number 18 of the 4th group and number 1 of the 1st group and number 47 of the 7th group. If we see table 2 and picture 2, it is proved that mineral water has effects to accelerate oxygen flow to erythrocytes or acceptors’ diffusion and as well energy supply because membrane’s peroxide endurance of erythrocytes’ fourth compartment of the white rabbit decreased by 1.11-1.12 times under the influence of Otgontenger resorts number 18 and 1 of the 4th and 1st groups respectively and as well osmos’s endurance property of membrane of the erythrocytes’ 4th compartment decreased by 1.2-1.22 times compared to those not taken it. If we see picture 3, it is proved that mineral water has effects to accelerate oxygen flow to erythrocytes or acceptors’ diffusion and energy supply because membrane’s peroxide endurance of erythrocytes fourth compartment of the white rabbit decreased by 1.11-1.12 times under the influence of Otgontenger resorts with numbers 18 and 1 of the 4th and 1st groups respectively and as well osmos’s endurance property of membrane of the erythrocytes’ 4th compartment decreased by 1.2-1.22 times compared to those not taken it.From picture 4 it can be seen that under the influence of some types of Otgontenger mineral water as 18th number of the 4th group and the first number of the 1st group MDA contained in the second compartment of the white rabbit decreases by 1.11-1.12 times compared to the control group not taken and as well osmoses’ endurance of the erythrocytes’ 4th compartment membrane declines by 1.2-1.22 times which means they have effects to accelerate oxygen flow to erythrocytes or acceptors’ diffusion and consequently energy supply. We can see from picture 5 that under influence of mineral water with number 47 of the 7th group, the oxidise-ferment activity of erythrocytes’ second compartment serum has decreased two times for the control group compared to the ones not taken the mineral water. Moreover, the oxidise-ferment activity of erythrocytes’ first compartment declined by 1.2 times as a result of the mineral water with number 47 of the 7th group. That means that the mineral water suppresses the ferment activity of lipoproteidlipaza but makes the flow of redoxy-line protons accelerated.Conclusion: It has been defined that Otgontenger mineral water has high antitoxic effects to reduce free radicals like DPHH.
2. AIRWAY FOREIGN BODY DIAGNOSIS AND TREATMENT
Dulguun E ; Zorigtbaatar M ; Ganbayar L ; Tsendjav A ; Gankhuyag V ; Adyasuren J
Journal of Surgery 2016;19(1):29-32
Introduction: The aim of this study was tostudy the pattern of foreign-body aspiration inthe tracheobronchial tree as well as the successrate of rigid bronchoscopy in children admittedto the National Center for Maternal and ChildHealth, Mongolia during 2012-2016.Materials and Methods: In this crosssectionaldescriptive study, the required datawere collected from the medical reports ofall children under the age of 13 years withsuspected foreign-body aspiration who wereadmitted and underwent explorative flexibleand rigid bronchoscopy during 2012-2016. Thedata was retrospective viewed.Results: Among 40 patients with aconfirmed aspiration, 57.5% (23) were malesand 42.5% (17) were females. 42.5% were1-3 years old. The most common complaints(symptoms) of patients were non-productivecough (82.5%), wheezing (52.5%) andrespiratory distress (22.5%). The mostfrequently aspirated foreign bodies were nuts(peanuts). In total, 57.5% of foreign bodieswere lodged in the right bronchial tree. In 100%of cases, the foreign body was completelyextracted by bronchoscope. The majority ofcases were admitted more than 24 hours afterthe occurrence of aspiration, and pneumoniawas the most common complication. In X-rayfindings Golitsknyekhta Yakobsona’s symptomswere in 10 /25%/ cases.Conclusion: Patient history, especiallyinitial suspicion of aspiration, coughing,wheezing and respiratory distress, can behelpful in the diagnosis of foreign-bodyaspiration. All foreign bodies were removed bybronchoscope /100%/ without complications.In X-ray findings Golitsknyekhta Yakobsona’ssymptoms were in 10 /25%/ cases.
3. LAPAROSCOPIC NEEDLE-ASSISTED REPAIR OF INGUINAL HERNIA (LNAR)
Chuluunkhuu D ; Baterdene E ; Unurjargal J ; Zorigtbaatar M ; Ganbayar L ; Tsendjav A
Journal of Surgery 2016;19(1):33-36
Introduction: In our hospital we didfirst laparoscopic surgery in October 2013with doctors from Samsung Medical Center,Seoul, Korea. In NCMCH we did about 3000operations per year, and about 400 of themtakes inguinal hernia. Bilateral and unilateralbig hernias has a lot of complications,like swelling, recurrence etc. Goals andobjectives:comparison between LNAR andstandard open technique of hernia repair.Calculate the outcome, hospital stay,recurrence, complications.Materials and Methods: We describeour technique and experience with thelaparoscopic needle-assisted repair of inguinalhernia (LNAR). We report retrospectively 42cases (hernias) from September 2014 toDecember 2015. We have 2 groups. In firstgroup we did standard open hernia repair in23 (54,7%)cases, in second group we didLNAR in 19 (45,3%) cases. Hernia repairis accomplished with a one port needleassistedtechnique. After identification of apatent processusvaginalis, the internal ringis encircled in an extraperitoneal plane usinga 22G-Touhy needle for placement of apurse-string suture, tied extracorporally, andburied beneath the skin. The technique wasstandardized for second group cases. Inguinalhernias were laparoscopically repaired in19patients (16 boys and 3 girls) age range1year to 16 years. All 19 cases had bilateralrepair. Mean operating time for bilateral was45 min. No complications in second group.For the first group we had 18 boys and 5girls same age range. Mean operating time1hour 20min.8 minor complications wereidentified(8 swelling) and 1 recurrence. Postoperativedata show our technique is safewith no complication. No recurrence.Results: First group: we had 18 boysand 5 girls,age range 1year to 16 years.Mean operating time1 hour 20min. 8 minorcomplications were identified (8 swelling)and 1 recurrence. Second group: we had16 boys and 3 girls, age range 1year to 16years. All 19 cases had bilateral repair. Meanoperating time for bilateral was 45 min. Nocomplications.Conclusions: In our technique meantime was shorter than in standard opentechnique. Post-operative data show ourtechnique is safe with no complication.No recurrence. Furthermore, laparoscopyobjectively identifies asymptomatic or occultcontralateral defect, uses a smaller incision,and eliminates dissection of the cordstructures potentially reducing the risk ofcord injury.
4. LAPAROSCOPIC ECHINOCOCCECTOMY IN CHILDREN
Dulguun E ; Zorigtbaatar M ; Ganbayar L
Journal of Surgery 2016;19(1):57-59
Introduction: In Mongolia laparoscopicsurgery starts 25 years ago, in our center /NCMCH/ we start laparoscopic surgery fromOctober 2013.Materials and metods: The articleanalyzes the results of treatment of 2patients 16 years old girl and 14 yearsold boy, who underwent laparoscopicechinococcectomy. Abdominal ultrasoundshowed solitary echinococcosis in VII liversegment, diameters is 9.8cm and 7.4cm.The echinococcus cysts were removed bylaparoscopy. In residual cavity of echinococcuscyst was performed laparoscopic coagulationof the inner wall of the fibrous capsulewithout drainage. After laparoscopic liverechinococcectomy postoperative period wasmuch more favorable than after traditionalechinococcectomy.Results: to evaluate the therapeutictactics and ways to improve the eliminationof residual cavities after laparoscopicechinococcectomy of liver in children.Conclusions: The hospital stay in thepostoperative period was 3 bed days.Laparoscopic echinococcectomy is goingwithout postoperative complications,without residuals, reduce the duration ofpostoperative hospital stays.
5. THE RESULTS OF LAARP PROCEDURE OF SANORECTAL MALFORMATIONS
Nurjanar R ; Zorigtbaatar M ; Chuluunhuu D ; Erdenedalai A
Journal of Surgery 2016;20(2):62-66
Introduction: The number of patientswith various types of Anorectal malformations(AMR) are constantly increasing by ourdata. We estimate an average 10 incidenceof ARM per year and it is as twice increasedas compared to 5 patients in 1996-2000.Thepurpose of this study was to determine anincidence, types of ARM and evaluate theresults of PSARP procedure using Kelly’sscoring system.Materials and methods: A total 124patients were retrospectively reviewed andanalyzed.There were 38 patients with ARMwithout fistula, 86 patients with fistula, withprevalence of perineal fistula, 2 cloacas, 6with rectal stenosis, 7 with ectopic anus and2 with acquired atresia due to postoperativesevere anal stenosis.Results: 63 patients underwent colostomyprocedure during neonatal age, 31 patientsunderwent primary operations, 73 patientsunderwent PSARP procedure as a secondaryoperation between 4 months to 1 year ofage and 6 patients underwent redo PSARPprocedure at 8-10 years of age.One patientwith 2 cm of common channel of cloacaunderwent total urogenital mobilization at 2years of age.In 9 patients PSARP procedurewas combined with laparoscopy (LAARPprocedure with ligation of bladderneck andprostatic fistula), in 4 with laparotomy. 6patients underwent buginage of perinealfistula followed by primary PSARPprocedure.Another 6 patients underwentPSARP procedure and closure of colostomyat the same time.In 21 patients we observed6 types of complications such as severeanal stenosis acquired atresia, mislocatedanus, constipation, soiling, and recurrenceof rectouretral fistula and mortality duringneonatal age.Conclusion: The favorable results ofPSARP procedure were achieved in 71.4% ofpatients using Kelly’s clinical scoring system.Usage of Laparoscopy during abdominalstage is favorable, while it allows closureof colostomy at the same time. There is apotential for increasing of primary PSARPprocedure as though there is a prevalence oflow type malformations with perineal fistula.
6. RESULT OF KASAI OPERATION, CHILDREN LIVER TRANSPLANTATION IN MONGOLIA
Chuluunkhuu D ; Zorigtbaatar M ; Nurjanar R ; Ganbayr L ; Otgonsuren G ; Dashaa M ; Enkhzul P ; Khandmaa B ; Sergelen O ; Bat-Ireedui B ; Ganzorig B ; Pagaldulam M ; Saruul G ; Tsendjav A
Journal of Surgery 2016;20(2):56-61
Introduction: Biliary Atresia is a fibroobliterativedisorder of the intra andextrahepatic bile ducts in infancy, which isgoing progressively cholestatic liver disease.The failed Kasaiportoenterostomy requiresliver transplantation. The goal of this studyis to show the outcome of Kasai operation,recent improvement and correlation the datato overseas.Methods and Materials: This study wasconducted in the department of generalsurgery of National Center for Maternal andChild Health of Mongolia between 2010 and2016 on a total of 66 infancies with biliaryatresia.Results: Patient diagnosed with biliaryatresia, which performed Kasai operationwithin first 2 months the outcome is verygood early and late post-operation period.There were 3 patients with 10 year survival, 4patients with 5-10 year and 28 patients with5 year survival after Kasai operation. The mostcomport age for liver transplantation is 1 yearlater after Kasai operation in Mongolia. Livertransplantation programme is necessary forMongolian pediatric surgery, and we thoughtour team was assembled.Conclusion: The children with biliary atresiaperform the Kasai operation within 2 monthsthe outcome is very good. Children with biliaryatresia often experience long wait times fortransplant unless exception points are grantedto reflect severity of disease.In Mongolia livertransplantation done in 2 child.