Objective: To compare the anterior capsule opacification and contraction of lens following femtosecond laser-assisted cataract surgery versus conventional phacoemulsification for cataract patients with diabetes. Methods: A non-randomized control study was carried out.Eighty-five eyes of 85 cataract patients with diabetes were included from March 2015 to August 2016 in Xiamen Eye Center.The patients were divided into 2 groups based on the different surgeries.Forty-three eyes of 43 patients in the femtosecond laser group received femtosecond laser-assisted phacoemulsification and completed the 5.3 mm capsulorhexis using the Alcon LenSx femtosecond laser platform.Forty-two eyes of 42 patients in the conventional surgery group underwent conventional phacoemulsification group and performed 5.3 mm continuous circular capsulorhexis under the guidance of Alcon VERION.Anterior capsule opacification (ACO) was graded according to Werner's method.The area of anterior capsular opening was calculated by using Image Pro Plus 6 software.The number of eyes in different grades of ACO and anterior capsule opening area between two groups were compared at 1 month, 3 months and 6 months after operation. Results: Initial anterior capsular opening area was not significantly different between the femtosecond laser group and the conventional phacoemulsification group (t=0.003, P=0.958). The anterior capsule opening area in the two groups among different time-points after operations was significantly different (F_group=73.602, P<0.001; F_time=378.895, P<0.001), and anterior capsule opening areas were smaller in the conventional phacoemulsification group than those in the femtosecond laser group at various time points after operation (all at P<0.001). At 1 month after suigery, grade Ⅰ of the ACO was found in 29 eyes (67.4%) in the femtosecond laser group and 26 eyes (61.9%) in the conventional phacoemulsification group, and there was no significant difference between two groups (P=0.133). At 3 months after surgery, the incidence rate of grade Ⅱ of ACO was 11.6% (5/43) in the femtosecond laser group, which was lower than than that in the conventional phacoemulsification group(66.7%, 28/42), showing a significant difference between them (P<0.001). At the 6th month after operation, the incidence rate of grade Ⅲ of ACO in the femtosecond laser group was 14.0%(6/43), which was lower than that in the conventional phacoemulsification group(73.8%, 31/42), with a significant difference between them (P<0.001). Conclusions Femtosecond laser-assisted cataract surgery for cataract is a good choose patients with diabetes mellitus because of reducing the occurrence of ACO and the contraction of anterior capsule.

Objective:To evaluate the precision of Pentacam AXL in measuring the parameters required for intraocular lens (IOL) calculation and compare the results with those obtained with Lenstar LS900.Methods:A cross-sectional study was designed.Seventy patients (91 eyes) with age-related cataract treated in Xiamen Eye Center Affiliated to Xiamen University from March to August, 2017 to receive cataract surgery were collected.Biometry measurements in 91 eyes of 70 cataract patients were performed by the same examiner with Pentacam AXL and Lenstar LS900 before surgery.The axial length (AL), keratometry (K) and anterior chamber depth (ACD) were obtained.The differences between the two devices were analyzed by paired-samples t test and Pearson correlation analysis.Differences and correlation of biometry measurements obtained with two biometers were analyzed.The agreement of the two biometers was analyzed by Bland-Altman plot.Written informed consent was obtained from each subject prior to entering the study cohort.The study protocol was approved by the Ethics Committee of Xiamen Eye Center Affiliated to Xiamen University (No.XMYKZX-LW-2017-003). Results:The mean values of AL were (23.39±1.34)mm and (23.42±1.36)mm, mean keratometry (Km) values were (43.96±1.53)D and (44.00±1.51)D, respectively, and the ACD values were (2.89±0.38)mm and (2.88±0.37)mm respectively measured by Pentacam AXL and Lenstar LS900, and the differences were not statistically significant ( P= 0.906, 0.855, 0.811), but all of the three biometrey measurements showed good linear correlation ( r = 0.999, 0.975, 0.991; all at P<0.05). AL, Km and ACD between Pentacam AXL and Lenstar LS900 showed good agreements analyzed by Bland-Altman plot, and the respective 95% limits of agreement (95%LoA) for AL and ACD were -0.11 to 0.07 mm and -0.09 to 0.12 mm, while 95% LoA for Km was -0.70 to 0.62 D. Conclusions:Pentacam AXL can provide accurate parameters for IOL calculation, which has a good agreement with Lenstar LS900, and the AL and ACD parameters can be used interchangeably.