1.Investigation on Prevalence and Associated Factors of Fatty Liver among College Staffs of Qingdao
Chinese Journal of Prevention and Control of Chronic Diseases 2006;0(05):-
Objective To investigate the prevalence and its related factor of fatty liver among the college staffs.Methods 1 348 college staffs were investigated on their medical history,gender,age,food and behavior habit,and examined on their body height,body weight and blood pressure,while detected on the liver function,blood sugar and blood lipids,and diagnosed by the result of B uhrasound test.Results The prevalence rate of fatty liver in college staffs was 16.69%,which higher in male than in female(x~2=10.40,P
2.Expression of TNF-? and IgE in Peripheral Blood of Children Patients with Mycoplasma pneumoniae Infection and Bronchial Asthma
Zongliang YAO ; Lanyin LI ; Aihua WAN
Chinese Journal of Nosocomiology 2006;0(05):-
OBJECTIVE To study the expression of the level of tumor necrosis factor alpha(TNF-?) and total IgE in Mycoplasma pneumoniae(MP) infection and bronchial asthma,and to analyze its relation with disease severity.METHODS The enzyme-linked immunosorbent assay(ELISA) was adopted to measure the level TNF-? and radioimmunoassay(RIA) to measure IgE in 42 children patients with asthma and MP infection as a test group,and 36 healthy children as a control group.RESULTS Among patients with asthma and MP infection TNF-? [(37.96?9.76)?g/L] and IgE [(310.57?30.39) mg/ml] had a significantly higher level than control group [(16.39?6.87)?g/L and (201.50?16.98)mg/ml],the statistical differences were significant(t=11.23;t=19.56 P
3.Expressions of PCNA, c-erbB-2, p53, ER and PR in tissues adjacent to breast cancer
Zongliang JIA ; Zijing LIN ; Xiangming CHE ; Lu YAO
Journal of Xi'an Jiaotong University(Medical Sciences) 2010;31(2):212-216
Objective To detect the expressions of proliferating cell nuclear antigen (PCNA), C-erbB-2, p53, estrogen receptor (ER) and progesterone receptor (PR) in order to explore the proper margin for breast conservative surgery on Chinese women. Methods We collected 40 resection specimens from breast cancer patients who had received radical surgery. Then we divided each specimen into primary tumor group and hyperplasia and gene expression characteristics of PCNA, c-erbB-2, p53, ER and PR were measured by pathological and immunohistochemical assay in the five groups. Results With the further distance from the primary tumor, the proportions of high-risk disease and positive gene expressions of PCNA, c-erbB-2 and p53 in paracarcinoma tissues gradually decreased (P<0.05). Higher risk and more positive expressions were related to paracarcinoma was no correlation of PCNA, ER and PR expressions adjacent to breast cancer with tissue differentiation and lymph node metastasis (P>0.05). a safe and appropriater region for breast conservative surgery.