Objective To investigate the protective effects of Ginkgo Biloba leaves(EGb) preconditioning on liver graft in rat liver transplantation.Methods Male Sprague-Dawley rats were used as donors and(recipients) of orthotopic liver transplantation(OLT).The rats were randomly divided into EGb group,normal saline(NS) control group and sham operation(SO) group.The animals were killed at 2h,6h,24h after graft reperfusion.Plasma samples were collected for ALT and AST test.Liver tissues were collected to detect the expression of TNF-?mRNA and Bcl-2mRNA by RT-PCR.Also,liver tissues were used to detect rat(liver) histological change and apoptosis by TUNEL.Results The serum levels of ALT in EGb group were(significantly) lower than the NS group(P

OBJECTIVE: To evaluate the efficacy and safety of Dinggui Oil Capsule in treating irritable bowel syndrome (IBS) with stagnation of qi and cold. METHODS: A prospective, randomized, placebo-controlled, double-blind clinical study was undertaken. One hundred and ninety-eight patients with IBS and syndrome of stagnation of qi and cold were randomly divided into high-dose Dinggui Oil group (DGO-H, 1.2 g, 3 times daily; n=66), low-dose Dinggui Oil group (DGO-L, 0.8 g, 3 times daily, n=66), and placebo group (placebo, 5.0 g, 3 times daily, n=66). Patients in the three groups were all treated for 2 weeks. RESULTS: The total significant effective rates for IBS were 54.1%, 28.8% and 21.9% in the DGO-H, DGO-L, and placebo groups, and the total effective rates for the syndrome of stagnation of qi and cold were 54.1%, 25.8% and 23.4% in the three groups, respectively. Dinggui Oil Capsule showed a higher efficacy than the placebo in relieving the abdominal pain (P<0.01). No adverse effects were found in this trial. CONCLUSION: Dinggui Oil Capsule is effective and safe in relieving abdominal pain due to IBS with stagnation of qi and cold.

Objective:To explore effects of family aerobic exercise combined with respiratory training on pulmonary function, self-care ability and quality of life in chronic obstructive pulmonary disease (COPD) patients with frailty.Methods:A total of 86 COPD patients with frailty who were treated in the Outpatient Department in the First Affiliated Hospital of Zhengzhou University from September 2018 to March 2019 were selected by the convenient sampling method. They were randomly divided into the control group ( n=43) and the observation group ( n=43) . The control group was given routine health education while the observation group was given family aerobic exercise combined with respiratory training guidance. After 3 months of intervention, pulmonary function meters were used to compare lung function indexes between two groups. Barthel index and COPD Assessment Test (CAT) were used to compare activity of daily living (ADL) and quality of life of patients. Results:38 patients in the observation group and 40 patients in the control group completed the study. After 3 months of intervention, there was no statistically significant difference in lung function indexes between the observation group and the control group ( P> 0.05) . After 3 months of intervention, the Barthel index score of the observation group (71.28±10.02) was higher than that of the control group while CAT score (13.68±5.16) was lower than that of the control group. The differences between the two groups were statistically significant ( t=-2.102, 2.736; P< 0.05) . Conclusions:Family aerobic exercise combined with respiratory training can improve the lung function of COPD patients with frailty and improve their self-care ability and quality of life, which has certain clinical application values.