Pulmonary thromboembolism is a common clinical critical disease with high mortality.Because of its pathogenesis and risk factors are complex and diverse,and the lack of specific clinical manifestations,pulmonary thromboem-bolism is easily never? diagnosed and misdiagnosed.Pulmonary thromboembolism results from a combination of endothelial injury,blood hypercoagulability/blood stasis,and endothelial injury is the main mechanism of the body for developing pulmonary thromboembolism.This article reviews the research progress of vascular endothelial injury markers in pulmonary thromboembolism.