1.Status quo of nutritional risks, malnutrition and nutritional support of inpatients with neoplasms
Lin ZHANG ; Zixia XU ; Suyun LI
Chinese Journal of Modern Nursing 2017;23(11):1470-1473
Objective To investigate the status quo of nutritional risks, malnutrition and nutritional support of inpatients with neoplasms and to provide a theoretical basis for making targeted clinic nutritional support standards and training programs.Methods Totally 421 patients with neoplasms who were admitted in Wuhan Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology between October 2015 and April 2016 were selected as respondents by cross-sectional survey and convenience sampling, and investigated with self-made nutritional support questionnaires based on Nutritional Risk Screening 2002 (NRS 2002) and China's real nursing practice.Results The incidence of malnutrition of the 421 patients was 44.2%, and the incidence of nutritional risks was 68.6%. The incidence of nutritional risks of patients with gastrointestinal neoplasms was higher than that of those patients with other neoplasms (χ2=24.541, 4.405;P<0.05); 92.6% of patients received nutritional support, 76.2% of which received parenteral nutrition and 14.5% received enteral nutrition; the incidence of gastrointestinal complications among those patients who received enteral nutrition was up to 30.2%, and the incidence of mechanical complications among those patients who received parenteral nutrition was up to 13.4%; the nursing achievement rates of the patients who received enteral nutrition and parenteral nutrition were 41.8% and 61.6%, respectively.Conclusions Inpatients with neoplasms show high incidence of nutritional risks and malnutrition. Therefore, healthcare workers should standardize the nutritional risk management for inpatients with neoplasms and strengthen the nutrition nursing training and quality control for nurses so as to reduce nutritional support-related complications among inpatients with neoplasms and accelerate their recovery.
2.Detection rate and risk factors analysis of motoric cognitive risk syndrome
Shanshan SHEN ; Jiaojiao CHU ; Yinghong YANG ; Xingkun ZENG ; Liyu XU ; Zixia LIU ; Lingyan CHEN ; Xujiao CHEN
Chinese Journal of Geriatrics 2019;38(6):620-623
Objective To investigate the detection rate of motoric cognitive risk syndrome (MCR)and explore the possible risk factors.Methods A total of 429 elderly patients from geriatric department of Zhejiang Hospital from October 2014 to September 2018 were recruited in the crosssectional study.General information and functional assessment including fall history,self-reported visual impairment and hearing impairment,depressive symptom,cognitive function and gait speed were collected.Patients with MCR were screened out according to the MCR diagnostic criteria.Multiple logistic regression analysis was used to analyze the associated risk factors.Results Seventeen patients(4.0%)met the MCR diagnostic criteria.The proportions of obesity,polypharmacy,cerebral vascular diseases,self-reported hearing impairment,depressive symptoms and slow gait were higher in MCR patients than in non-MCR patients(P<0.05).Compared with non-MCR patients,MCR patients had lower mini mental state examination (MMSE) scores (P < 0.01).After adjusting for associated confounding factors,multiple logistic regression analysis showed obesity (OR =3.74,95 % CI:1.14-12.23,P < 0.05) and depressive symptoms (OR =5.79,95% CI:1.76-19.06,P < 0.01) were risk factors for MCR.Conclusions MCR is not uncommon in elderly patients.Obesity and depressive symptoms are closely associated with an increased risk of MCR.
3.Research progress on clinical manifestations and mechanism of radiation-induced taste dysfunction in head and neck cancers
Zixia LI ; Xingchen PENG ; Xin XU
Chinese Journal of Radiation Oncology 2023;32(6):557-561
Taste is a critical sensory function for human as it supports sustenance and alerts the body to toxins. Taste dysfunction is a common side effect of radiotherapy for the head and neck cancers, which is often accompanied by oral mucositis in the early stage. It is associated with anorexia, anxiety and depression, leading to declined quality of life and treatment tolerance. The incidence of radiation-induced taste dysfunction is high, and its clinical manifestations include increased taste threshold, tastelessness, and persistent bitter, sour or metallic taste, which exert significant effect upon the quality of life. At present, effective therapeutic measures for radiation-induced taste dysfunction are still lacking. In this article, research progresses on clinical characteristics and the potential mechanisms of radiation-induced taste dysfunction were reviewed, aiming to provide reference for the mechanism, prevention and treatment for taste dysfunction.