Objective To investigate the effect of transcranial direct current stimulation (tDCS) on aphasia recovery after stroke. Meth-ods From April, 2012 to January, 2013, 20 aphasic patients after stroke were enrolled in an A-B experiment design. During phase A, ten times of sham tDCS and language training (five days a week) were implemented, then ten times language training combined with tDCS (five days a week) were implemented in phase B. The treatment lasted for four weeks. Picture naming was measured for all patients before and af-ter treatment both in phase A and phase B. Results The D-value scores of picture naming before and after treatment were significantly more in phase B than in phase A in both treatment items and non-treatment items (t>3.030, P<0.05). Conclusion tDCS could raise the accuracy of picture naming in patients with aphasia after stroke.

ObjectiveTo observe the effects of different environmental intervention on neurofilament (NF) expression in rats after unilateral local cerebral infarction. MethodsAfter middle cerebral artery occluded (MCAO) by electric coagulation, 125 male SD rats were randomly divided into individual living group (n=30, living alone in small standard cages), social communication group (n=30, 5 as a group living in large standard stages ), learning group(n=30, 15 as a group living in exploratory cages), enriched environment group (n=30, 5 as a group living in EE cages) and sham operated group(n=5). The rats were randomly sacrificed at the 1st, 3rd, 7th, 14th, 21st, 28th day after MCAO. The expressions of NF in peri-ischemic cortex were detected with immunohistochemistry staining. ResultsThe expression of NF in the peri-ischemia cortex in enriched environment group and learning group was higher than that in other two groups (P<0.01) after 7 days, it also was higher in social communication group than that in individual living group (P<0.05). ConclusionEnriched environment and learning could enhance NF expression in rats after unilateral local cerebral infarction.

OBJECTIVETo explore whether bariatric surgery can decrease the incidence of obesity-related tumors in obesity patients.

METHODSRelevant studies comparing the incidence of obesity-related tumors in obesity patients between bariatric surgery and non- bariatric surgery were identified by search of PubMed, Medline, EBSCO, High Wire Press, OVID, EMbase, China hownet (CNKI) and Wanfang databases since the self-built database. In strict accordance with the standard after the screening, literature quality and extracted data were evaluated. Review manager 5.2 software was used to perform meta-analysis and sensitivity analysis. Inverted funnel chart was used to investigate the publication bias.

RESULTSFive articles including 108 954 patients were enrolled in the analysis. Among them, 26 218 cases were bariatric surgery group, and 82 736 cases of non-surgical weight loss were the control group. Meta analysis showed that bariatric surgery could obviously decrease the incidence of postoperative obesity-related tumor(RR=0.60, 95% CI:0.45-0.80, P=0.0005). Subgroup analysis showed that cancer risk difference of obesity-related tumor in male patients was not significant between two group, while the postoperative incidence of obesity-related tumor of female patients in bariatric surgery group was significantly lower compared to those female patients in control group(RR=0.68, 95% CI:0.61-0.77, P<0.01). During follow-up of 1 to 10 years, the incidence of obesity-related tumor in bariatric surgery group was significantly lower than that in control group(P<0.05). When follow-up was more than 10 years, the incidence of obesity-related tumors was similar between two groups(P=0.70).

CONCLUSIONBariatric surgery can decrease the overall risk of obesity-related cancer, especially for female patients, but with the prolongation of time, such effect of bariatric surgery is not obvious.

With rapid development of information technology,blended teaching model has gradually become mainstream teaching model in most colleges and universities.How to evaluate students'learning effect and analyze factors that affect students'per-formance is a key research direction of this teaching model.Taking blended teaching of Medical Immunology course in Xinxiang Medical University as an example,this paper introduces implementation process and evaluation system of blended teaching,analyzes main factors affecting students'performance and learning effect,and focuses on discussing influence of formative evaluation and"flipped classroom"on students'academic performance.