1.Contribution to the study on cholagogue effect of curcuma, zingiberaceae in North-Vietnam
Pharmaceutical Journal 1998;272(12):18-20
The test are on three groups of rat, each group of six lives. The results showed out both curcuma harmandii and curcuma trichosantha, in dose of 10g/kg of rat, continuously use for three days, increase the bile excretion of 114 percent and 112 percent compare with non drug groups of 100 percent. Drug's effect starts 2-3 hours after using and reaches the maximum after 4 hours. The effect lasts 3-4 hours for curcuma trichosantha, even longer for curcuma harmandii. These effects have no influence to total Bilrubin and bile density.
Cholagogues and Choleretics
;
Curcuma
;
Zingiberaceae
2.Identification and characterization of plant growth-promoting properties of bacterial endophytes from selected Zingiberaceae plants
Kingchan Malisorn ; Sirinapa Kabbun ; Sukanya Phuengjayaem ; Pawina Kanchanasin ; Somboon Tanasupawat
Malaysian Journal of Microbiology 2021;17(5):548-559
Aims:
This study aims to isolate, characterize and screen the plant growth-promoting bacteria from Zingiberaceae plants. Plant promoting activities such as indole-3-acetic acid (IAA), phosphate solubilization, zinc solubilization and nitrogen-fixing capabilities are determined, and the IAA production of selected isolates are optimized.
Methodology and results:
Endophytic bacteria were isolated from the plant samples by surface sterilization on nutrient agar (NA) plates and incubated at 30 °C for 2-3 days. The bacteria were identified based on their phenotypic characteristics and 16S rRNA gene sequence analyses. All isolates were identified as genera Bacillus, Lysinibacillus, Kerstersia, Klebsiella and Brucella. The isolates exhibited phosphate solubilization (1.5 ± 0.75-37.5 ± 8.75 Solubilization Index, SI), zinc solubilization (2.5 ± 0-60 ± 1.5 SI) and IAA production (0.1 ± 0.2-115.7 ± 1.6 µg/mL), while 3 isolates possessed nitrogen-fixing capabilities. Five isolates (PHAS-2, PWS-2, PWR-2, PHBS-2 and SCG-2) were selected for IAA optimization. Isolate PWR-2 produced the maximum IAA at 447.7 ± 0 µg/mL when tryptophan concentration was maintained at 1.0%.
Conclusion, significance and impact of study
Genera of bacteria included Bacillus, Lysinibacillus, Kerstersia, Klebsiella and Brucella were successfully isolated from Zingiberaceae plants. All the isolates showed the capability to produce IAA, while some isolates exhibited phosphate solubilization and zinc solubilization, and a few possessed nitrogen-fixing capabilities. The potential IAA production isolates could be applied for the enhancement of agricultural production that will be becoming a more widely accepted practice.
Plant Growth Regulators
;
Endophytes
;
Zingiberaceae
3.Anti-osteoporotic and Antioxidant Activities by Rhizomes of Kaempferia parviflora Wall. ex Baker.
Nguyen Phuong THAO ; Bui Thi Thuy LUYEN ; Sang Hyun LEE ; Hae Dong JANG ; Young Ho KIM
Natural Product Sciences 2016;22(1):13-19
In this report, we investigated the antioxidant (peroxyl radical-scavenging and reducing capacities) and anti-osteoporotic activities of extracts and isolated constituents (1 - 16) from the rhizomes of Kaempferia parviflora Wall. ex Baker on pre-osteoclastic RAW 264.7 cells. Compound 5 exhibited significant peroxyl radical-scavenging capacity, with TE value of 8.47 ± 0.52 µM, while compound 13 showed significant reducing capacity, with CUPRAC value of 5.66 ± 0.26 µM, at 10.0 µM. In addition, flavonoid compounds 2, 4, 6, 8, 10, 12, and terpene compound 15 showed significant inhibition of tartrate-resistant acid phosphatase (TRAP) in NF-κB ligand-induced osteoclastic RAW 264.7 cells, with values ranging from 16.97 ± 1.02 to 64.67 ± 2.76%. These results indicated that K. parviflora could be excellent sources for the antioxidant and anti-osteoporotic traditional medicinal plants.
Acid Phosphatase
;
Osteoclasts
;
Plants, Medicinal
;
Rhizome*
;
Zingiberaceae*
4.Antibiotic Components from the Rhizomes of Curcuma zedoaria.
Choon Sik JEONG ; Sang Hee SHIM
Natural Product Sciences 2015;21(3):147-149
Two terpenoids, including one uniquely aromatized one (1), were isolated from CH2Cl2-soluble fraction of MeOH extracts of Curcuma zedoaria. They were identified to be a sesquiterpene ketolactone (1) and orobanone (2), respectively on the basis of their NMR data. The structure of compound 1 was confirmed by X-ray chrystallography and the reported NMR assignments for 1 were revised in this study. Antibiotic activities for compounds 1 and 2 were evaluated using disk diffusion assay. Compound 1 showed potent antibacterial activities against Listeria monocytogenes and Staphylococcus pseudointermedius while compound 2 was active against Bacillus cereus.
Bacillus cereus
;
Curcuma*
;
Diffusion
;
Listeria monocytogenes
;
Rhizome*
;
Staphylococcus
;
Terpenes
;
Zingiberaceae
5.Nitric Oxide Inhibitory Constituents from the Fruits of Amomum tsao-ko
Jun Gu KIM ; Thi Phuong Linh LE ; Hye Ryeong HONG ; Jae Sang HAN ; Jun Hwi KO ; Seung Hyun LEE ; Mi Kyeong LEE ; Bang Yeon HWANG
Natural Product Sciences 2019;25(1):76-80
Bioactivity-guided fractionation of MeOH extract of the dried fruits of Amomum tsao-ko led to isolation of nine compounds (1 – 9). Their structures were elucidated by spectroscopic methods including extensive 1D and 2D-NMR, as alpinetin (1), naringenin-5-O-methyl ether (2), naringenin (3), hesperetin (4), 2′,4′,6′-trihydroxy-4-methoxy chalcone (5), tsaokoin (6), boesenbergin B (7), 4-hydroxyboesenbergin B (8), and tsaokoarylone (9). Of these, compound 8 was isolated from a natural source for the first time, which was previously reported as a synthetic product. The isolated compounds (1 – 9) were tested for their inhibitory effects on LPS-induced nitric oxide production in RAW 264.7 macrophages. Among them, three chalcone derivatives (compounds 5, 7, and 8) and a diarylheptanoid (compound 9) exhibited significant inhibitory activity on the NO production with IC₅₀ values ranging from 10.9 to 22.5 µM.
Amomum
;
Chalcone
;
Ether
;
Fruit
;
Macrophages
;
Nitric Oxide
;
Zingiberaceae
6.Research progress and discussion on traditional Chinese medicine properties of Kaempferia parviflora.
Jie WU ; Lin-Lin GUO ; Zhi-Qiang HUANG ; Rui ZHANG ; Ru-Ying TANG ; Jian-Jun ZHANG ; Chun WANG ; Lin-Yuan WANG
China Journal of Chinese Materia Medica 2021;46(8):1951-1959
Kaempferiae Parviflorae Rhizoma is the dried rhizome of Kaempferia parviflora in Zingiberaceae. It is originated and widely distributed in Thailand and other tropical and subtropical regions, where it has been used as food and medicine for thousands of years. K. parviflora is also planted in Yunnan and other places of China, but its traditional Chinese medicine properties are not clear, which greatly limits its compatibility with traditional Chinese medicines. In this article, the English and Chinese literatures of K. parviflora were searched from Web of Science, PubMed, Scopus, CNKI, Wanfang, and VIP databases for research and analysis. The medicinal properties of K. parviflora were preliminarily discussed based on the theory of traditional Chinese medicine under the guidance of clinical application and research literatures. The traditional Chinese medicine properties of K. parviflora were inferred as follows: flat, acrid, sweet. The channel tropisms of K. parviflora included kidney, spleen, stomach, and liver. The function of K. parviflora included tonifying kidney to strengthen essence, tonifying Qi and invigorating spleen, soothing liver and relieving depression. K. parviflora was clinically applied for the diseases such as syndrome of kidney essence deficiency, sex apathy, deficiency of spleen Qi, lassitude and asthenia, a weary spirit, obesity, diabetes, liver Qi stagnation, depression, and restless. The equivalent of dry power is 1.5 g·d~(-1) and the equivalent of decoction is 1.5-6 g·d~(-1). The determination of traditional Chinese medicine properties of K. parviflora has indeed laid a theoretical foundation for its application in the field of traditional Chinese medicine and enriched traditional Chinese medicine resources.
China
;
Drugs, Chinese Herbal
;
Medicine, Chinese Traditional
;
Rhizome
;
Thailand
;
Zingiberaceae
7.ISSR-PCR analysis in different species and populations of Rhizoma Curcumae.
Xiao-Hui WANG ; Xiao-Chuang TANG ; En-Xiu YANG ; De-Jun LIU ; Min LI ; Xiao-Kun LI
China Journal of Chinese Materia Medica 2008;33(18):2037-2040
OBJECTIVETo study the genetic diversity and genetic relationship in different species and populations of Curcuma by ISSR-PCR marker technique.
METHODEighty populations and 37 samples of Curcuma including C. phaeocaulis, C. kwangsiensis and C. wenyujin were studied by ISSR-PCR markers. The systematic diagram of Similar coefficient and genetic distance were set up by POPGEN32 software and clustered by UPGMA method.
RESULTA total of 65 loci were scored by 5 primers, among which 34 were polymorphic loci. The percentage of polymorphic loci was 52.3%. Genetic similarity coefficient changed from 0.6864 to 0.9997. Nei's gene diversity index (H), and Shannon information index (I) were 0.1521 and 0.2338. The inner genetic diversity of Curcuma species was lower than the outer.
CONCLUSIONThe genetic variation of different populations Curcuma was big. The inherited differentiation of inner populations was low. Different populations of Curcuma were related to character of species and geological distribution.
Genetic Variation ; genetics ; Polymerase Chain Reaction ; methods ; Polymorphism, Genetic ; genetics ; Species Specificity ; Zingiberaceae ; classification ; genetics
8.Studies on chemical constituents from rhizomes of Hedychium chrysoleucum.
Minghua LUO ; Lifen LEI ; Honghui LIN
China Journal of Chinese Materia Medica 2009;34(2):180-182
OBJECTIVETo investigate the chemical constituents from the rhizome o fHedychium chrysoleucum.
METHODThe compounds were isolated by column chromatography on silica gel. The structures were identified by NMR, IR and MS analyses.
RESULTSeven compounds were isolated and identified as hedychenone (1), coronarin A (2), yunnancoronarin A (3), coronarin E (4), beta-sitosterol (5), cryptomeridiol (6), and beta-eudesmol (7).
CONCLUSIONCompounds 1-7 were obtained from this plant for the first time.
Magnetic Resonance Spectroscopy ; Mass Spectrometry ; Organic Chemicals ; analysis ; isolation & purification ; Rhizome ; chemistry ; Spectrophotometry, Infrared ; Zingiberaceae ; chemistry
9.Phytochemistry and pharmacology of ornamental gingers, Hedychium coronarium and Alpinia purpurata: a review.
Eric Wei Chiang CHAN ; Siu Kuin WONG
Journal of Integrative Medicine 2015;13(6):368-379
In this review, the phytochemistry and pharmacology of two ornamental gingers, Hedychium coronarium (butterfly ginger) and Alpinia purpurata (red ginger), are updated, and their botany and uses are described. Flowers of H. coronarium are large, showy, white, yellow or white with a yellow centre and highly fragrant. Inflorescences of A. purpurata are erect spikes with attractive red or pink bracts. Phytochemical investigations on the rhizomes of H. coronarium generated research interest globally. This resulted in the isolation of 53 labdane-type diterpenes, with little work done on the leaves and flowers. Pharmacological properties of H. coronarium included antioxidant, antibacterial, antifungal, cytotoxic, chemopreventive, anti-allergic, larvicidal, anthelminthic, analgesic, anti-inflammatory, anti-urolithiatic, anti-angiogenic, neuro-pharmacological, fibrinogenolytic, coagulant and hepatoprotective activities. On the contrary, little is known on the phytochemistry of A. purpurata with pharmacological properties of antioxidant, antibacterial, larvicidal, cytotoxic and vasodilator activities reported in the leaves and rhizomes. There is much disparity in terms of research effort within and between these two ornamental gingers.
Alpinia
;
chemistry
;
Ginger
;
chemistry
;
Oils, Volatile
;
analysis
;
pharmacology
;
Plant Extracts
;
pharmacology
;
Zingiberaceae
;
chemistry
10.Determination of hedychenone in Hedychium yunnanense.
Qi-xin YAN ; Xiao-wen YE ; Qing ZHAO ; Jin-hua ZHAO ; Yong-cheng LIN
China Journal of Chinese Materia Medica 2005;30(20):1593-1595
OBJECTIVETo establish an HPLC method for determination of hedychenone in Hedychium yunnanense.
METHODC18 Chromatographic column was used, acetonitrile-water (9:1) as mobile phase, at flow rate of 1.0 mL x min(-1): The wavelength for detection was 235 nm.
RESULTThe linear range of hedychenone was 5.92-29.6 microg x mL(-1)(r = 0.9999). The average recovery was 99.0%, RSD of precision was less than 2%.
CONCLUSIONThe method is simple, effective and feasible, and can be used to evaluate the quality of the herb.
Chromatography, High Pressure Liquid ; methods ; Diterpenes ; analysis ; Plant Roots ; chemistry ; Plants, Medicinal ; chemistry ; Quality Control ; Zingiberaceae ; chemistry